Search Results - "IHARA, Nobuo"
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Down syndrome cell adhesion molecule like-1 (DSCAML1) links the GABA system and seizure susceptibility
Published in Acta neuropathologica communications (30-11-2020)“…The Ihara epileptic rat (IER) is a mutant model with limbic-like seizures whose pathology and causative gene remain elusive. In this report, via linkage…”
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Open‐field Behaviors and Water‐maze Learning in the F Substrain of Ihara Epileptic Rats
Published in Epilepsia (Copenhagen) (01-01-2006)“…Purpose: Genetically epileptic model rats, Ihara epileptic rat (IER/F substrain), have neuropathologic abnormalities and develop generalized convulsive…”
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Clobazam shows a different antiepileptic action profile from clonazepam and zonisamide in Ihara epileptic rats
Published in Epilepsy research (01-05-2002)“…Purpose: Clobazam (CLB, 1,5-benzodiazepine, 1,5-BZP) has been reported to show unique antiepileptic action profile distinguishing from standard 1,4-BZPs. To…”
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Altered hippocampal expression of neuropeptide Y, somatostatin, and glutamate decarboxylase in Ihara's epileptic rats and spontaneously epileptic rats
Published in Neuroscience letters (23-06-2000)“…By in situ hybridization and immunocytochemistry, expression of neuropeptide Y (NPY), somatostatin and glutamate decarboxylase 65 (GAD65) was studied in the…”
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Genetic analysis of cataract in Ihara epileptic rat
Published in Mammalian genome (01-03-2001)“…We analyzed the mode of inheritance of cataract in the Ihara epileptic rat (IER) by crossing experiments, and mapped cataract-related genes by linkage…”
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Morphometric investigation of the hippocampal formation in Ihara's genetically epileptic rats using magnetic resonance images and histopathology
Published in Neuropathology (01-06-1999)“…The newly developed Ihara's genetically epileptic rat (IGER) is thought to be a useful tool for studying epilepsy of the limbic type. Morphological changes in…”
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Morphological study of a hereditary rat cataract
Published in Experimental eye research (01-06-1990)“…Lenses of ICR/f stain rats with hereditary cataract were examined by light and electron microscopy. The earliest change was the frequent occurrence of…”
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Neuropathological study on a newly developed epileptic rat mutant with limbic-like seizures
Published in Psychiatry and clinical neurosciences (01-06-1995)Get more information
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ENZYME HISTOCHEMISTRY IN EXPERIMENTAL DIABETES MELLITUS II. FINDINGS ON SEVERAL ENZYME ACTIVITIES IN THE PARENCHYMAL ORGANS, MUSCULAR SYSTEM, INTESTINE, AND ADRENAL GLAND IN DIABETIC RABBITS
Published in Endocrinologia Japonica (1966)“…Reported here, is an investigation of changes in enzyme activities in the pancreatic islet cells (A-and B-cells) from Alloxan or Dithizone-induced diabetic…”
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ULTRASTRUCTURAL DEMONSTRATION OF NADPH OXIDASE ACTIVITY IN KUPFFER AND ENDOTHELIAL CELLS USING AN ISOLATED LIVER PERFUSION SYSTEM: COMPARISON BETWEEN ICR/D-STRAIN AND JCL: WISTAR-STRAIN RATS
Published in ACTA HISTOCHEMICA ET CYTOCHEMICA (01-01-1984)“…In order to cytochemically demonstrate the NADPH dependent H2O2 generation system in the sinusoidal lining cells of the liver, the authors applied the modified…”
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Effects of antiepileptics on two different types of seizures in a novel epileptic mutant rat (IGER)
Published in Japanese Journal of Pharmacology (1999)“…Iharas Genetically Epileptic Rat (IGER) is a mutant with circling seizures (CS) and generalized tonic-clonic convulsions (GTC), which develop around 2 and 5…”
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ENZYME HISTOCHEMISTRY IN EXPERIMENTAL DIABETES MELLITUS I. THE HISTOCHEMICAL FINDINGS IN THE PANCREATIC ISLET CELLS AT SUCCESSIVE INTERVALS FOLLOWING THE ADMINISTRATION OF DIABETOGENIC SUBSTANCES
Published in Endocrinologia Japonica (01-01-1965)“…The enzymatic activity changes in rabbit pancreatic islets were studied at various time intervals (from 15mins. to 48 hrs.) after the administration of…”
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ENZYME HISTOCHEMISTRY IN EXPERIMENTAL DIABETES MELLITUS: II. FINDINGS ON SEVERAL ENZYME ACTIVITIES IN THE PARENCHYMAL ORGANS, MUSCULAR SYSTEM, INTESTINE, AND ADRENAL GLAND IN DIABETIC RABBITS
Published in Endocrinologia Japonica (1966)“…Reported here, are the observations on various histochemical enzyme reactions in several organs (the liver;the kidney;the cardiac, diaphragm, and femoral…”
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SILVER BROMIDE METHOD AS MODIFIED FOR ELECTRON MICROSCOPIC DEMONSTRATION OF ETHYLENIC DOUBLE BONDS EXISTING IN CEROID-LIKE PIGMENT BODIES
Published in ACTA HISTOCHEMICA ET CYTOCHEMICA (01-01-1984)“…One of the histochemical characteristics of ceroid pigment is the existence of ethylenic double bonds in protein-bound unsaturated lipids. For…”
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THE EFFECTIVENESS OF OUR COLLOIDAL IRON METHOD IN THE ELECTRON-HISTOCHEMICAL DEMONSTRATION OF SULFHYDRYL AND DISULPHIDE WITH PARTICULAR REFERENCE TO PANCREATIC ZYMOGEN GRANULES
Published in ACTA HISTOCHEMICA ET CYTOCHEMICA (1975)“…The colloidal iron method here introduced is an improved form of the Chèvremont-Fréderic method for the SH+SS groups. The principal point of improvement is the…”
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ON MORPHOGENESIS OF THE ACID PHOSPHATASE ACTIVITY; ITS SIGNIFICANCE IN ADRENAL PIGMENTS FORMATION OF LANOLIN-TREATED RABBITS OR AGED RATS AND IN DEXTRAN STORAGE OF RAT LYMPH NODE MACROPHAGES
Published in ACTA HISTOCHEMICA ET CYTOCHEMICA (01-01-1978)“…The morphogenesis of ACPase activity was observed in the following experimental materials: 1) The parenchymal cells and macrophages of the adrenal cortex of…”
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Hereditary Neuronal Microdysgenesis and Acquired Lesions in the Hippocampal Formation of Ihara Epileptic Rat
Published in Epilepsia (Copenhagen) (01-09-2000)“…Purpose: Ccrebral dysplasia including neuronal microdysgcnesis is reported in a large series or cortical resections obtained from patients with medically…”
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Development of a novel rat mutant with spontaneous limbic-like seizures
Published in The American journal of pathology (01-07-1996)“…A new epileptic rat mutant with spontaneous seizures was developed by successive mating and selection from an inherited cataract rat. The procedures for…”
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Changes of immunoreactive neuropeptide Y, somatostatin and corticotropin-releasing factor (CRF) in the brain of a novel epileptic mutant rat, Ihara's genetically epileptic rat (IGER)
Published in Brain research (21-11-1997)“…Ihara's genetically epileptic rat (IGER) is a rat mutant with genetically scheduled spontaneous convulsions mimicking human limbic seizures. In the present…”
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