Search Results - "IGLESIAS, Luis E"

Large scale analysis of protein conformational transitions from aqueous to non-aqueous media by Rueda, Ana Julia Velez, Monzon, Alexander Miguel, Ardanaz, Sebastián M, Iglesias, Luis E, Parisi, Gustavo

“…Biocatalysis in organic solvents is nowadays a common practice with a large potential in Biotechnology. Several studies report that proteins which are…”
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Biocatalytic approaches applied to the synthesis of nucleoside prodrugs by Iglesias, Luis E., Lewkowicz, Elizabeth S., Medici, Rosario, Bianchi, Paola, Iribarren, Adolfo M.

“…Nucleosides are valuable bioactive molecules, which display antiviral and antitumour activities. Diverse types of prodrugs are designed to enhance their…”
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Structural and evolutionary analysis unveil functional adaptations in the promiscuous behavior of serum albumins by Velez Rueda, Ana Julia, Benítez, Guillermo Ignacio, Sommese, Leandro Matías, Ardanaz, Sebastián M., Borucki, Estefanía L., Palopoli, Nicolas, Iglesias, Luis E., Parisi, Gustavo

“…Promiscuous activities have been related to the capacity to catalyze reactions different from those a protein has evolved to sustain. In this work, we…”
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An enzymatic alternative for the synthesis of nucleoside 5′-monophosphates by Gudiño, Esteban D., Santillán, Julia Y., Iglesias, Luis E., Iribarren, Adolfo M.

“…•A new synthesis of nucleoside 5′-monophosphates based on the use of two enzymes.•The first step is catalyzed by phospholipase D; the second, by phospholipase…”
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Bovine serum albumin-catalysed cross aldol condensation: Influence of ketone structure by Ardanaz, Sebastián M., Borucki, Estefanía L., Velez Rueda, Ana J., Parisi, Gustavo, Iribarren, Adolfo M., Iglesias, Luis E.

“…[Display omitted] •Bovine serum albumin (BSA) catalyses the cross aldol condensation of a set of ketones.•BSA is active at mild temperature and in ethanol, a…”
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A Mild Procedure for Enone Preparation Catalysed by Bovine Serum Albumin in a Green and Easily Available Medium by Ardanaz, Sebastián M., Velez Rueda, Ana J., Parisi, Gustavo, Iribarren, Adolfo M., Iglesias, Luis E.

“…A simple and mild procedure to obtain α,β-unsaturated ketones from acetone and a set of benzaldehydes is described. The approach applies bovine serum albumin…”
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Deprotection of peracetylated methyl d-ribosides through enzymatic alcoholysis: Different recognition of the anomers by Iñigo, Sabrina, Porro, Marisa Taverna, Montserrat, Javier M., Iglesias, Luis E., Iribarren, Adolfo M.

“…The anomers methyl 2,3,5-tri- O-acetyl-α- d-ribofuranoside and methyl 2,3,5-tri- O-acetyl-β- d-ribofuranoside showed a different behaviour in the Candida…”
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An efficient and mild access to N-acetyl protected purine nucleosides based on a chemoselective enzymatic hydrolysis by Palacio, Cyntia M., Sabaini, María B., Iribarren, Adolfo M., Iglesias, Luis E.

“…•N-Monoacetylated purine nucleosides were chemoselectively obtained in 88–100%.•Best results afforded by Candida antarctica lipase B and acylase I (Asp…”
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Preparation of potential 3-deazauridine and 6-azauridine prodrugs through an enzymatic alcoholysis by Zinni, María A., Iglesias, Luis E., Iribarren, Adolfo M.

“…A set of 3-deazauridine and 6-azauridine peracylated derivatives were regioselectively deacylated through Candida antarctica B lipase (CAL B) catalysed…”
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Lipases in green chemistry: acylation and alcoholysis on steroids and nucleosides by Baldessari, Alicia, Iglesias, Luis E

“…In this article, we describe the application of lipases in acylation and alcoholysis reactions on steroids and nucleosides. In the field of steroids, a variety…”
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Enzymatic regioselective and complete deacetylation of two arabinonucleosides by Sabaini, María B., Zinni, María A., Mohorčič, Martina, Friedrich, Jožefa, Iribarren, Adolfo M., Iglesias, Luis E.

“…Candida antarctica lipase B (CAL-B)-catalysed regioselective deacetylation of 2′,3′,5′-tri- O-acetyl-1-β- d-arabinofuranosyluracil ( 1) and 2′,3′,5′-tri-…”
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Two new dialkoxycarbonylated nucleosides obtained through a regioselective enzymatic alcoholysis by Capello, Mariana, Imanishi, Leandro, Iglesias, Luis E, Iribarren, Adolfo M

“…Two new compounds, 2',3'-di-O-ethoxycarbonyluridine and 2',3'-di-O-ethoxycarbonylinosine, were obtained through a Candida antarctica lipase B catalysed…”
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Deacetylation of furanosides using banana as biocatalyst by Taverna-Porro, Marisa, Iglesias, Luis E., Montserrat, Javier M., Iribarren, Adolfo M.

“…The deacylation under hydrolytic conditions of methyl 2,3,5-tri- O-acetyl-α- d-ribofuranoside, methyl 2,3,5-tri- O-acetyl-β- d-ribofuranoside, methyl…”
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Microbial hydrolysis of acetylated nucleosides by PANERO, Julieta, TRELLES, Jorge, RODANO, Valeria, MONTSERRAT, Javier M, IGLESIAS, Luis E, LEWKOWICZ, Elizabeth S, IRIBARREN, Adolfo M

“…Enzymatic hydrolysis of acetylated nucleosides using microbial whole cells has been carried out for the first time. Unlike Candida antarctica B…”
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A mild and quantitative procedure for the removal of nucleoside alkoxycarbonyl groups using pig liver esterase or Candida antarctica B lipase by Capello, Mariana, González, Mariana, Rodríguez, Silvio D., Iglesias, Luis E., Iribarren, Adolfo M.

“…Nucleoside carbonates and carbamates 1– 8 were quantitatively deprotected by pig liver esterase (PLE) catalysed hydrolysis at pH 7 and 60 °C. ▪ A set of eight…”
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Albumin-catalysed synthesis of flavanones by Borucki, Estefanía L., Iribarren, Adolfo M., Iglesias, Luis E.

“…Flavanones are a family of phytochemicals that have regained importance over the last decade due to their diverse biological activity. The conventional…”
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Enzymatic alcoholysis of 3′,5′-di-O-acetyl-2′-deoxynucleosides by Zinni, Marı́a A, Rodrı́guez, Silvio D, Pontiggia, Rodrigo M, Montserrat, Javier M, Iglesias, Luis E, Iribarren, Adolfo M

“…Candida antarctica-B (CAL-B) lipase-catalysed alcoholysis of a set of 3′,5′-di-O-acetyl-2′-deoxynucleosides (1a–e) gave the corresponding…”
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Regioselective preparation of 2', 3'-di-O-acylribonucleosides carrying lipophilic acyl groups through a lipase-catalysed alcoholysis by ZINNI, Maria A, IGLESIAS, Luis E, IRIBARREN, Adolfo M

“…Candida antarctica B lipase-catalysed alcoholysis of 2', 3', 5'-tri-O-hexanoyluridine (1a), 2', 3', 5'-tri-O-dodecanoyluridine (1b), 2', 3',…”
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Enzymatic resolution of (±)-1-ferrocenylethylamine by Iglesias, Luis E, Rebolledo, Francisca, Gotor, Vicente

“…(±)-1-Ferrocenylethylamine was resolved by a highly enantioselective acetylation catalyzed by Candida antarctica B lipase…”
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A simple and efficient enzymatic procedure for the deprotection of two base labile chlorinated purine ribosides by RONCAGLIA, Diana I, SCHMIDT, Alejandro M, IGLESIAS, Luis E, IRIBARREN, Adolfo M

“…Base-labile 6-chloro-2',3',5'-tri-O-acetylpurine riboside (1c) and 2-amino-6-chloro-2',3',5'-tri-O-acetylpurine riboside (1d) were fully deacetylated through…”
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