Search Results - "IDOATE, Miguel A"
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Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma
Published in The New England journal of medicine (30-06-2022)“…A total of 12 pediatric patients with diffuse intrinsic pontine glioma were treated with a direct infusion of an oncolytic virus, followed by radiotherapy. The…”
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Prognostic Value of Residual Fluorescent Tissue in Glioblastoma Patients After Gross Total Resection in 5-Aminolevulinic Acid-Guided Surgery
Published in Neurosurgery (01-06-2013)“…Abstract BACKGROUND: There is evidence in the literature supporting that fluorescent tissue signal in fluorescence-guided surgery extends farther than tissue…”
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Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas
Published in PloS one (01-11-2011)“…We undertook this study to understand how the transcription factor Sox2 contributes to the malignant phenotype of glioblastoma multiforme (GBM), the most…”
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Expression of sirtuin 1 and 2 is associated with poor prognosis in non-small cell lung cancer patients
Published in PloS one (27-04-2015)“…Sirtuin 1 (SIRT1) and sirtuin 2 (SIRT2) are NAD+-dependent protein deacetylases involved in the regulation of key cancer-associated genes. In this study we…”
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Machine Learning Quantification of Intraepithelial Tumor-Infiltrating Lymphocytes as a Significant Prognostic Factor in High-Grade Serous Ovarian Carcinomas
Published in International journal of molecular sciences (01-11-2023)“…The prognostic and predictive role of tumor-infiltrating lymphocytes (TILs) has been demonstrated in various neoplasms. The few publications that have…”
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A new animal model of atrophy–hypertrophy complex and liver damage following Yttrium-90 lobar selective internal radiation therapy in rabbits
Published in Scientific reports (02-02-2022)“…Lobar selective internal radiation therapy (SIRT) is widely used to treat liver tumors inducing atrophy of the treated lobe and contralateral hypertrophy. The…”
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A Reassessment of the Barrier Effect of the Physis against Metaphyseal Osteosarcoma: A Comprehensive Pathological Study with Its Radiological and Clinical Follow-Up Correlations
Published in Diagnostics (Basel) (09-02-2022)“…Osteosarcoma is a primary malignant bone tumor usually arising at the metaphysis of long bones, particularly around the knee. The physis has been regarded as a…”
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Silencing of Histone Deacetylase 6 Decreases Cellular Malignancy and Contributes to Primary Cilium Restoration, Epithelial-to-Mesenchymal Transition Reversion, and Autophagy Inhibition in Glioblastoma Cell Lines
Published in Biology (Basel, Switzerland) (26-05-2021)“…Glioblastoma multiforme, the most common type of malignant brain tumor as well as the most aggressive one, lacks an effective therapy. Glioblastoma presents…”
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Stratification of resectable lung adenocarcinoma by molecular and pathological risk estimators
Published in European journal of cancer (1990) (01-09-2015)“…Abstract Background Mortality in early stage, resectable lung cancer is sufficiently high to warrant consideration of post-surgical treatment. Novel markers to…”
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Modification of Breast Cancer Milieu with Chemotherapy plus Dendritic Cell Vaccine: An Approach to Select Best Therapeutic Strategies
Published in Biomedicines (17-01-2023)“…The addition of dendritic cell vaccines (DCV) to NAC could induce immune responses in those patients with residual disease (RD) by transforming the tumor…”
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Neoadjuvant nivolumab modifies the tumor immune microenvironment in resectable glioblastoma
Published in Nature medicine (01-03-2019)“…Glioblastoma is the most common primary central nervous system malignancy and has a poor prognosis. Standard first-line treatment, which includes surgery…”
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PD-1/PD-L1 Blockers in NSCLC Brain Metastases: Challenging Paradigms and Clinical Practice
Published in Clinical cancer research (15-08-2020)“…Immune checkpoint inhibitors (ICI) have revolutionized the management of advanced non-small cell lung cancer (NSCLC). However, most pivotal phase III trials…”
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Panobinostat Potentiates Temozolomide Effects and Reverses Epithelial–Mesenchymal Transition in Glioblastoma Cells
Published in Epigenomes (01-03-2018)“…Glioblastoma is the most common form of glioma, as well as the most aggressive. Patients suffering from this disease have a very poor prognosis. Surgery,…”
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A Quantitative Digital Analysis of Tissue Immune Components Reveals an Immunosuppressive and Anergic Immune Response with Relevant Prognostic Significance in Glioblastoma
Published in Biomedicines (21-07-2022)“…Objectives: Immunostimulatory therapies using immune checkpoint blockers show clinical activity in a subset of glioblastoma (GBM) patients. Several inhibitory…”
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Henoch-Schönlein purpura associated with celiac disease
Published in Journal of the American Academy of Dermatology (01-06-2011)Get full text
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Phosphoinositide 3-kinase p85beta regulates invadopodium formation
Published in Biology open (15-10-2014)“…The acquisition of invasiveness is characteristic of tumor progression. Numerous genetic changes are associated with metastasis, but the mechanism by which a…”
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Cytology Smears in the Era of Molecular Biomarkers in Non-Small Cell Lung Cancer: Doing More With Less
Published in Archives of pathology & laboratory medicine (1976) (01-03-2018)“…- The rapid advances in targeted therapies in non-small cell lung cancer (NSCLC) make the optimization and implementation of cytology specimens for molecular…”
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Tubastatin A, an inhibitor of HDAC6, enhances temozolomide‑induced apoptosis and reverses the malignant phenotype of glioblastoma cells
Published in International journal of oncology (01-05-2019)“…Glioblastoma or grade IV astrocytoma is the most common and lethal form of glioma. Current glioblastoma treatment strategies use surgery followed by…”
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