Search Results - "ICLI, BASAK"

Emerging Roles for MicroRNAs in Diabetic Microvascular Disease: Novel Targets for Therapy by Zhang, Yu, Sun, Xinghui, Icli, Basak, Feinberg, Mark W.

“…Abstract Chronic, low-grade systemic inflammation and impaired microvascular function are critical hallmarks in the development of insulin resistance…”
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MicroRNA-181b Improves Glucose Homeostasis and Insulin Sensitivity by Regulating Endothelial Function in White Adipose Tissue by Sun, Xinghui, Lin, Jibin, Zhang, Yu, Kang, Sona, Belkin, Nathan, Wara, Akm K, Icli, Basak, Hamburg, Naomi M, Li, Dazhu, Feinberg, Mark W

“…RATIONALE:The pathogenesis of insulin resistance involves dysregulated gene expression and function in multiple cell types, including endothelial cells (ECs)…”
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MicroRNA-615-5p Regulates Angiogenesis and Tissue Repair by Targeting AKT/eNOS (Protein Kinase B/Endothelial Nitric Oxide Synthase) Signaling in Endothelial Cells by Icli, Basak, Wu, Winona, Ozdemir, Denizhan, Li, Hao, Cheng, Henry S, Haemmig, Stefan, Liu, Xin, Giatsidis, Giorgio, Avci, Seyma Nazli, Lee, Nathan, Guimaraes, Raphael Boesch, Manica, Andre, Marchini, Julio F, Rynning, Stein Erik, Risnes, Ivar, Hollan, Ivana, Croce, Kevin, Yang, Xianbin, Orgill, Dennis P, Feinberg, Mark W

“…OBJECTIVE—In response to tissue injury, the appropriate progression of events in angiogenesis is controlled by a careful balance between pro and antiangiogenic…”
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Role of Krüppel-like factors in leukocyte development, function, and disease by Cao, Zhuoxiao, Sun, Xinghui, Icli, Basak, Wara, Akm Khyrul, Feinberg, Mark W.

“…The Krüppel-like transcription factor (KLF) family participates in diverse aspects of cellular growth, development, differentiation, and activation. Recently,…”
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MicroRNA-26a Regulates Pathological and Physiological Angiogenesis by Targeting BMP/SMAD1 Signaling by Icli, Basak, Wara, A.K.M, Moslehi, Javid, Sun, Xinghui, Plovie, Eva, Cahill, Meghan, Marchini, Julio F, Schissler, Andrew, Padera, Robert F, Shi, Jianru, Cheng, Hui-Wen, Raghuram, Srilatha, Arany, Zoltan, Liao, Ronglih, Croce, Kevin, MacRae, Calum, Feinberg, Mark W

“…RATIONALE:The rapid induction and orchestration of new blood vessels are critical for tissue repair in response to injury, such as myocardial infarction, and…”
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MiR-409-3p targets a MAP4K3-ZEB1-PLGF signaling axis and controls brown adipose tissue angiogenesis and insulin resistance by Becker-Greene, Dakota, Li, Hao, Perez-Cremades, Daniel, Wu, Winona, Bestepe, Furkan, Ozdemir, Denizhan, Niosi, Carolyn E., Aydogan, Ceren, Orgill, Dennis P., Feinberg, Mark W., Icli, Basak

“…Endothelial cells (ECs) within the microvasculature of brown adipose tissue (BAT) are important in regulating the plasticity of adipocytes in response to…”
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Regulation of impaired angiogenesis in diabetic dermal wound healing by microRNA-26a by Icli, Basak, Nabzdyk, Christoph S, Lujan-Hernandez, Jorge, Cahill, Meghan, Auster, Michael E, Wara, A.K.M, Sun, Xinghui, Ozdemir, Denizhan, Giatsidis, Giorgio, Orgill, Dennis P, Feinberg, Mark W

“…Abstract Wound healing is a physiological reparative response to injury and a well-orchestrated process that involves hemostasis, cellular migration,…”
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Deficiency of miR-409-3p improves myocardial neovascularization and function through modulation of DNAJB9/p38 MAPK signaling by Bestepe, Furkan, Fritsche, Colette, Lakhotiya, Kartik, Niosi, Carolyn E., Ghanem, George F., Martin, Gregory L., Pal-Ghosh, Ruma, Becker-Greene, Dakota, Weston, James, Hollan, Ivana, Risnes, Ivar, Rynning, Stein Erik, Solheim, Liv Heidi, Feinberg, Mark W., Blanton, Robert M., Icli, Basak

“…Angiogenesis is critical for tissue repair following myocardial infarction (MI), which is exacerbated under insulin resistance or diabetes. MicroRNAs are…”
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Bone marrow–derived CMPs and GMPs represent highly functional proangiogenic cells: implications for ischemic cardiovascular disease by Wara, Akm Khyrul, Croce, Kevin, Foo, ShiYin, Sun, Xinghui, Icli, Basak, Tesmenitsky, Yevgenia, Esen, Fehim, Rosenzweig, Anthony, Feinberg, Mark W.

“…Clinical studies using bone marrow–derived proangiogenic cells (PACs) have demonstrated modest improvements of function and/or perfusion of ischemic myocardium…”
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MicroRNA-26a Silencing in a Murine Model of Diabetic Wound Healing by Nabzdyk, Christoph S., MD, Icli, Basak, PhD, Lujan-Hernandez, Jorge, MD, Cahill, Meghan, Giatsidis, Giorgio, MD, Orgill, Dennis P., MD, FACS, Feinberg, Mark W., MD

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Nanotechnology-based approach in plastic surgery for diabetic wound healing by Lujan-Hernandez, Jorge R., MD, Icli, Basak, MS, PhD, Cahill, Meghan, BS, Lancerotto, Luca, MD, Yu, Nanze, MD, Hassan, Kazi Zayn, BS, Succar, Julien, MD, Khouri, Roger K., BS, Feinberg, Mark W., MD, Orgill, Dennis P., MD, PhD, FACS

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MicroRNAs in dysfunctional adipose tissue: cardiovascular implications by Icli, Basak, Feinberg, Mark W

“…In this review, we focus on the emerging role of microRNAs, non-coding RNAs that regulate gene expression and signaling pathways, in dysfunctional adipose…”
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An emerging role for the miR-26 family in cardiovascular disease by Icli, Basak, Dorbala, Pranav, Feinberg, Mark W

“…Abstract In response to acute myocardial infarction (MI), a complex series of cellular and molecular signaling events orchestrate the myocardial remodeling…”
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MICRORNA-MEDIATED REGULATION OF SMAD1 IN THE VASCULAR ENDOTHELIUM PROMOTES CELL GROWTH ARREST by Icli, Basak

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Abstract 19181: MicroRNA Regulation of Adipose Browning and Glucose Uptake Improves Cardiometabolic Disease by Bestepe, Furkan, Fritsche, Colette M, Persing, Sarah, Ruemmele, Brooke, Powers, Sarah, Chatterjee, Abhishek, Huggins, Gordon, Icli, Basak

“…Abstract only The prevalence of obesity is on the rise worldwide. Brown adipose tissue (BAT), a highly vascularized organ, is activated in response to cold…”
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MicroRNA-181b regulates NF-κB-mediated vascular inflammation by Sun, Xinghui, Icli, Basak, Wara, Akm Khyrul, Belkin, Nathan, He, Shaolin, Kobzik, Lester, Hunninghake, Gary M, Vera, Miguel Pinilla, Blackwell, Timothy S, Baron, Rebecca M, Feinberg, Mark W

“…EC activation and dysfunction have been linked to a variety of vascular inflammatory disease states. The function of microRNAs (miRNAs) in vascular EC…”
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Systemic Delivery of MicroRNA-181b Inhibits Nuclear Factor-κB Activation, Vascular Inflammation, and Atherosclerosis in Apolipoprotein E–Deficient Mice by Sun, Xinghui, He, Shaolin, Wara, A.K.M, Icli, Basak, Shvartz, Eugenia, Tesmenitsky, Yevgenia, Belkin, Nathan, Li, Dazhu, Blackwell, Timothy S, Sukhova, Galina K, Croce, Kevin, Feinberg, Mark W

“…RATIONALE:Activated nuclear factor (NF)-κB signaling in the vascular endothelium promotes the initiation and progression of atherosclerosis. Targeting…”
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Abstract 13092: Regulation of SARS-CoV-2, Viral Entry Proteins ACE2 and TMPRSS2, and Interferon Genes by Host MicroRNAs by Pierce, Jacob B, Simion, Viorel, Icli, Basak, Perez-Cremades, Daniel, Cheng, Henry, Feinberg, Mark W

“…IntroductionInfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for coronavirus disease 2019, can cause…”
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Computational Analysis of Targeting SARS-CoV-2, Viral Entry Proteins ACE2 and TMPRSS2, and Interferon Genes by Host MicroRNAs by Pierce, Jacob B, Simion, Viorel, Icli, Basak, Pérez-Cremades, Daniel, Cheng, Henry S, Feinberg, Mark W

“…Rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for coronavirus disease 2019 (COVID-19), has led to a…”
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MicroRNA‐135a‐3p regulates angiogenesis and tissue repair by targeting p38 signaling in endothelial cells by Icli, Basak, Wu, Winona, Ozdemir, Denizhan, Li, Hao, Haemmig, Stefan, Liu, Xin, Giatsidis, Giorgio, Cheng, Henry S., Avci, Seyma Nazli, Kurt, Merve, Lee, Nathan, Guimaraes, Raphael Boesche, Manica, Andre, Marchini, Julio F., Rynning, Stein Erik, Risnes, Ivar, Hollan, Ivana, Croce, Kevin, Orgill, Dennis P., Feinberg, Mark W.

“…ABSTRACTAngiogenesis is a critical process in repair of tissue injury that is regulated by a delicate balance between pro‐ and antiangiogenic factors. In…”
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