Search Results - "ICHIKAWA, AKIHIRO"
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Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis
Published in Nature communications (17-07-2019)“…Ferroptosis is a necrotic form of regulated cell death (RCD) mediated by phospholipid peroxidation in association with free iron-mediated Fenton reactions…”
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Chaperone‐mediated autophagy receptor modulates tumor growth and chemoresistance in non–small cell lung cancer
Published in Cancer science (01-11-2020)“…Chaperone‐mediated autophagy (CMA) is a lysosomal degradation pathway of selective soluble proteins. Lysosome‐associated membrane protein type 2a (LAMP2A) is…”
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Prognostic impact of preoperative FDG-PET positive lymph nodes in lung cancer
Published in International journal of clinical oncology (01-01-2021)“…Background 2-[ 18 F] Fluoro-D-deoxyglucose positron emission tomography (FDG-PET) is an appropriate diagnostic procedure for staging lung cancer. However,…”
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Involvement of GPx4-Regulated Lipid Peroxidation in Idiopathic Pulmonary Fibrosis Pathogenesis
Published in The Journal of immunology (1950) (15-10-2019)“…The imbalanced redox status in lung has been widely implicated in idiopathic pulmonary fibrosis (IPF) pathogenesis. To regulate redox status, hydrogen peroxide…”
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Azithromycin attenuates myofibroblast differentiation and lung fibrosis development through proteasomal degradation of NOX4
Published in Autophagy (03-08-2017)“…Accumulation of profibrotic myofibroblasts is involved in the process of fibrosis development during idiopathic pulmonary fibrosis (IPF) pathogenesis. TGFB…”
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Involvement of Lamin B1 Reduction in Accelerated Cellular Senescence during Chronic Obstructive Pulmonary Disease Pathogenesis
Published in The Journal of immunology (1950) (01-03-2019)“…Downregulation of lamin B1 has been recognized as a crucial step for development of full senescence. Accelerated cellular senescence linked to mechanistic…”
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Clinicopathologic Significance of False-Positive Lymph Node Status on FDG-PET in Lung Cancer
Published in Clinical lung cancer (01-05-2021)“…2-[18F] Fluoro-d-deoxyglucose (FDG) positron emission tomography (PET) is a relevant diagnostic procedure for staging lung cancer. However, accurate evaluation…”
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Chaperone-Mediated Autophagy Suppresses Apoptosis via Regulation of the Unfolded Protein Response during Chronic Obstructive Pulmonary Disease Pathogenesis
Published in The Journal of immunology (1950) (01-09-2020)“…Cigarette smoke (CS) induces accumulation of misfolded proteins with concomitantly enhanced unfolded protein response (UPR). Increased apoptosis linked to UPR…”
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Impaired TRIM16-Mediated Lysophagy in Chronic Obstructive Pulmonary Disease Pathogenesis
Published in The Journal of immunology (1950) (01-07-2021)“…Insufficient autophagic degradation has been implicated in accelerated cellular senescence during chronic obstructive pulmonary disease (COPD) pathogenesis…”
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Involvement of Parkin‐mediated mitophagy in the pathogenesis of chronic obstructive pulmonary disease‐related sarcopenia
Published in Journal of cachexia, sarcopenia and muscle (01-06-2022)“…Background Sarcopenia is characterized by the loss of skeletal muscle mass and strength and is associated with poor prognosis in patients with chronic…”
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Prostaglandin E-Major Urinary Metabolite (PGE-MUM) as a Tumor Marker for Lung Adenocarcinoma
Published in Cancers (03-06-2019)“…: Prostaglandin E2 (PGE2) is metabolized to prostaglandin E-major urinary metabolite (PGE-MUM). Enhanced cyclooxygenase-2 (COX-2) expression demonstrated in…”
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Pirfenidone inhibits myofibroblast differentiation and lung fibrosis development during insufficient mitophagy
Published in Respiratory research (02-06-2017)“…Pirfenidone (PFD) is an anti-fibrotic agent used to treat idiopathic pulmonary fibrosis (IPF), but its precise mechanism of action remains elusive…”
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Analysis of complete response by MRI following neoadjuvant chemotherapy predicts pathological tumor responses differently for molecular subtypes of breast cancer
Published in Oncology letters (01-01-2013)“…In the present study, clinical tumor response following neoadjuvant chemotherapy (NAC) was diagnosed by magnetic resonance imaging (MRI) and…”
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Concurrent Chemoradiotherapy Followed by Consolidation Chemotherapy With Bi-Weekly Docetaxel and Carboplatin for Stage III Unresectable, Non-Small-Cell Lung Cancer: Clinical Application of a Protocol Used in a Previous Phase II Study
Published in International journal of radiation oncology, biology, physics (01-04-2012)“…Purpose To assess the clinical applicability of a protocol evaluated in a previously reported phase II study of concurrent chemoradiotherapy followed by…”
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Binding of sialyl Lewis X antigen to lectin-like receptors on NK cells induces cytotoxicity and tyrosine phosphorylation of a 17-kDa protein
Published in Biochimica et biophysica acta (01-09-2006)“…Natural killer (NK) cells mediate cytotoxicity through cell-surface receptors including lectin-like receptors. We have investigated whether sialyl Lewis X (sLe…”
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In-plane anisotropy of the magnetic and the electric properties of the Fe pnictide Ba(Fe1−xCox)2As2
Published in Journal of the Korean Physical Society (01-08-2013)“…The anisotropy of the electronic and the magnetic properties within the FeAs planes of Co(2%)-doped BaFe 2 As 2 has been investigated by using 75 As nuclear…”
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Evaluation of the Effect of Tumor Position on Standardized Uptake Value Using Time-of-Flight Reconstruction and Point Spread Function
Published in Asia oceania journal of nuclear medicine and biology (01-01-2016)“…Objective(s): The present study was conducted to examine whether the standardized uptake value (SUV) may be affected by the spatial position of a lesion in the…”
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Therapeutic Effect of Linac-based Stereotactic Radiotherapy with a Micro-multileaf Collimator for the Treatment of Patients with Brain Metastases from Lung Cancer
Published in Japanese journal of clinical oncology (01-02-2010)“…Objective To assess the efficacy of hypofractionated linac-based stereotactic radiotherapy with a micro-multileaf collimator (mMLC) in lung cancer patients…”
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Impurity Effects in Nodal Extended s- and Nodeless d-Wave Superconductors: Gap Symmetry of BiS^sub 2^-Based Layered Superconductors
Published in Journal of the Physical Society of Japan (15-11-2018)“…In BiS2-based layered superconductors, the existence of gap nodes on Fermi-surface curves has been suggested from angle-resolved photoemission spectroscopy…”
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