Search Results - "ICHIHASHI, MASAMITSU"

Matcha and Its Components Control Angiogenic Potential by IWAI, Ryota, ISHII, Takeshi, FUKUSHIMA, Yoichi, OKAMOTO, Tadashi, ICHIHASHI, Masamitsu, SASAKI, Yasuto, MIZUATNI, Ken-ichi

“…The brain needs the appropriate capillary networks to maintain normal brain function. Since previous studies showed age-related decrease in the cortical…”
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The maximal cumulative solar UVB dose allowed to maintain healthy and young skin and prevent premature photoaging by Ichihashi, Masamitsu, Ando, Hideya

“…The young facial skin of children with a smooth healthy appearance changes over time to photoaged skin having mottled pigmentation, solar lentigines, wrinkles,…”
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Possible Involvement of Dermal Fibroblasts in Modulating Nrf2 Signaling in Epidermal Keratinocytes by Tsuruta, Yoshinobu, Katsuyama, Yushi, Okano, Yuri, Ozawa, Toshiyuki, Yoshimoto, Satoshi, Ando, Hideya, Masaki, Hitoshi, Ichihashi, Masamitsu

“…Epidermal keratinocytes protect themselves by cooperating with neighboring cells against internal and external stresses, which leads not only to the…”
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Approaches to Identify Inhibitors of Melanin Biosynthesis via the Quality Control of Tyrosinase by Ando, Hideya, Kondoh, Hirofumi, Ichihashi, Masamitsu, Hearing, Vincent J.

“…Tyrosinase, a copper-containing glycoprotein, is the rate-limiting enzyme critical for melanin biosynthesis in specialized organelles termed melanosomes that…”
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Extracellular Environment-Controlled Angiogenesis, and Potential Application for Peripheral Nerve Regeneration by Saio, Shingo, Konishi, Kanna, Hohjoh, Hirofumi, Tamura, Yuki, Masutani, Teruaki, Iddamalgoda, Arunasiri, Ichihashi, Masamitsu, Hasegawa, Hiroshi, Mizutani, Ken-Ichi

“…Endothelial cells acquire different phenotypes to establish functional vascular networks. Vascular endothelial growth factor (VEGF) signaling induces…”
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Riboflavin Plays a Pivotal Role in the UVA-Induced Cytotoxicity of Fibroblasts as a Key Molecule in the Production of H2O2 by UVA Radiation in Collaboration with Amino Acids and Vitamins by Yoshimoto, Satoshi, Kohara, Nana, Sato, Natsu, Ando, Hideya, Ichihashi, Masamitsu

“…To investigate environmental factors that contribute to ultraviolet A (UVA)-induced oxidative stress, which accelerates the senescence and toxicity of skin…”
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Spatiotemporally Dependent Vascularization Is Differently Utilized among Neural Progenitor Subtypes during Neocortical Development by Komabayashi-Suzuki, Mariko, Yamanishi, Emiko, Watanabe, Chisato, Okamura, Megumi, Tabata, Hidenori, Iwai, Ryota, Ajioka, Itsuki, Matsushita, Jun, Kidoya, Hiroyasu, Takakura, Nobuyuki, Okamoto, Tadashi, Kinoshita, Kazuo, Ichihashi, Masamitsu, Nagata, Koh-ichi, Ema, Masatsugu, Mizutani, Ken-ichi

“…To facilitate efficient oxygen and nutrient delivery, blood vessels in the brain form three-dimensional patterns. However, little is known about how blood…”
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Exopolysaccharides Isolated from Milk Fermented with Lactic Acid Bacteria Prevent Ultraviolet-Induced Skin Damage in Hairless Mice by Morifuji, Masashi, Kitade, Masami, Fukasawa, Tomoyuki, Yamaji, Taketo, Ichihashi, Masamitsu

“…We studied the mechanism by which fermented milk ameliorates UV-B-induced skin damage and determined the active components in milk fermented with lactic acid…”
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SOCS7-Derived BC-Box Motif Peptide Mediated Cholinergic Differentiation of Human Adipose-Derived Mesenchymal Stem Cells by Kanno, Hiroshi, Matsumoto, Shutaro, Yoshizumi, Tetsuya, Nakahara, Kimihiro, Shinonaga, Masamichi, Kubo, Atsuhiko, Fujii, Satoshi, Ishizuka, Yasuyuki, Tanaka, Masaki, Ichihashi, Masamitsu, Murata, Hidetoshi

“…Adipose-derived mesenchymal stem cells (ADMSCs) are a type of pluripotent somatic stem cells that differentiate into various cell types such as osteoblast,…”
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Dermal Fibroblasts Internalize Phosphatidylserine-Exposed Secretory Melanosome Clusters and Apoptotic Melanocytes by Ando, Hideya, Yoshimoto, Satoshi, Yoshida, Moemi, Shimoda, Nene, Tadokoro, Ryosuke, Kohda, Haruka, Ishikawa, Mami, Nishikata, Takahito, Katayama, Bunpei, Ozawa, Toshiyuki, Tsuruta, Daisuke, Mizutani, Ken-Ichi, Yagi, Masayuki, Ichihashi, Masamitsu

“…Pigmentation in the dermis is known to be caused by melanophages, defined as melanosome-laden macrophages. In this study, we show that dermal fibroblasts also…”
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Horse-Derived Ceramide Accentuates Glucosylceramide Synthase and Ceramide Synthase 3 by Activating PPARβ/δ and/or PPARγ to Stimulate Ceramide Synthesis by Igarashi, Tami, Yanagi, Hiroki, Yagi, Masayuki, Ichihashi, Masamitsu, Imokawa, Genji

“…Horse-derived ceramide (HC), which contains galactosylceramides as its main component, significantly improves skin symptoms when applied topically to patients…”
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Aging of the Vascular System and Neural Diseases by Watanabe, Chisato, Imaizumi, Tsutomu, Kawai, Hiromi, Suda, Kazuma, Honma, Yoichi, Ichihashi, Masamitsu, Ema, Masatsugu, Mizutani, Ken-ichi

“…Vertebrates have acquired complex high-order functions facilitated by the dispersion of vascular and neural networks to every corner of the body. Blood vessels…”
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Melanin pigment interrupts the fluorescence staining of mitochondria in melanocytes by Ando, Hideya, Ph.D, Ohagi, Yoshiaki, B.S, Yoshida, Moemi, B.S, Yoshimoto, Satoshi, B.S, Higashi, Yusuke, M.S, Yagi, Masayuki, B.S, Monji, Keisuke, M.D, Yagi, Mikako, Ph.D, Uchiumi, Takeshi, M.D., Ph.D, Kang, Dongchon, M.D., Ph.D, Ichihashi, Masamitsu, M.D., Ph.D

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Omeprazole, a Gastric Proton Pump Inhibitor, Inhibits Melanogenesis by Blocking ATP7A Trafficking by Matsui, Mary S., Petris, Michael J., Niki, Yoko, Karaman-Jurukovska, Nevena, Muizzuddin, Neelam, Ichihashi, Masamitsu, Yarosh, Daniel B.

“…Omeprazole is a proton pump inhibitor used in the treatment of peptic ulcer disease and gastrosophageal reflux disease and acts by irreversibly blocking ATP4A,…”
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Quasi-drugs developed in Japan for the prevention or treatment of hyperpigmentary disorders by Ando, Hideya, Matsui, Mary S, Ichihashi, Masamitsu

“…Excess production of melanin or its abnormal distribution, or both, can cause irregular hyperpigmentation of the skin, leading to melasma and age spots. To…”
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Role of the ubiquitin proteasome system in regulating skin pigmentation by Ando, Hideya, Ichihashi, Masamitsu, Hearing, Vincent J

“…Pigmentation of the skin, hair and eyes is regulated by tyrosinase, the critical rate-limiting enzyme in melanin synthesis by melanocytes. Tyrosinase is…”
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Complete Absence of Cockayne Syndrome Group B Gene Product Gives Rise to UV-Sensitive Syndrome but Not Cockayne Syndrome by Horibata, Katsuyoshi, Iwamoto, Yuka, Kuraoka, Isao, Nicolaas G. J. Jaspers, Kurimasa, Akihiro, Oshimura, Mitsuo, Ichihashi, Masamitsu, Tanaka, Kiyoji, Hanawalt, Philip C.

“…UV-sensitive syndrome ( UV s S) is a rare autosomal recessive disorder characterized by photosensitivity and mild freckling but without neurological…”
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8-oxoguanine formation induced by chronic UVB exposure makes Ogg1 knockout mice susceptible to skin carcinogenesis by KUNISADA, Makoto, SAKUMI, Kunihiko, TOMINAGA, Yohei, BUDIYANTO, Arief, UEDA, Masato, ICHIHASHI, Masamitsu, NAKABEPPU, Yusaku, NISHIGORI, Chikako

“…8-Oxoguanine is one of the oxidative DNA damages that can result in stable mutations. The Ogg1 gene encodes the repair enzyme 8-oxoguanine-DNA glycosylase,…”
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A new lipophilic pro-vitamin C, tetra-isopalmitoyl ascorbic acid (VC-IP), prevents UV-induced skin pigmentation through its anti-oxidative properties by Ochiai, Yasunobu, Kaburagi, Satoko, Obayashi, Kei, Ujiie, Nobuyuki, Hashimoto, Satoru, Okano, Yuri, Masaki, Hitoshi, Ichihashi, Masamitsu, Sakurai, Hiromu

“…Vitamin C, which is a strong anti-oxidant, plays an important role in maintaining physiological states. In dermatology, Vitamin C is used for treatment of…”
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Effects of platinum and palladium nanocolloid on macrophage polarization in relevance to repigmentation of vitiligo by Minamiyama, Yukiko, Ishikawa, Mami, Shibata, Takakazu, Tsuji, Gaku, Nishikata, Takahito, Takemura, Shigekazu, Ichihashi, Masamitsu

“…Background Elevated oxidative stress is accepted to be the initial event in vitiligo leading to the final pathological regulation of immune systems known as…”
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