Pseudo-Bartter's Syndrome due to Furosemide Abuse : Report of a Case and an Analytical Review of Japanese Literature

Pseudo-Bartter's Syndrome due to Furosemide Abuse : Report of a Case and an Analytical Review of Japanese Literature

Batter's syndrome characteristically exhibits the constellation of hypokalemic alkalosis, normotensive hyperreninism, hyperalodosteronism, hyporesponsiveness to pressor agent and juxtaglomerular cell hyperplasia. Recently, metabolic mimicry of Batter's syndrome by vomiting, diarrhea, laxat...

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Bibliographic Details
Published in:Japanese Journal of Medicine Vol. 20; no. 3; pp. 216 - 221
Main Authors: TAJIRI, Junichi, NAKAYAMA, Mahito, SATO, Tatsuo, IAOZAKI, Sadao, UCHINO, Katsuyoshi
Format: Journal Article
Language:English
Published: Japan The Japanese Society of Internal Medicine 01-01-1981
Subjects:
Adolescent
Adult
Aged
Bartter Syndrome - chemically induced
Bartter Syndrome - diagnosis
Bartter Syndrome - physiopathology
Calcium - urine
Diagnosis, Differential
Female
Furosemide - adverse effects
Humans
Hyperaldosteronism - chemically induced
Hypokalemia
Kidney - physiopathology
Male
Middle Aged
Nephrocalcinosis
Nephrocalcinosis - etiology
Normotension
Plasma aldosterone concentration
Plasma renin activity
Substance-Related Disorders - complications
Substance-Related Disorders - physiopathology
Uric Acid - blood
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Description
Summary:Batter's syndrome characteristically exhibits the constellation of hypokalemic alkalosis, normotensive hyperreninism, hyperalodosteronism, hyporesponsiveness to pressor agent and juxtaglomerular cell hyperplasia. Recently, metabolic mimicry of Batter's syndrome by vomiting, diarrhea, laxatives and diuretics abuse has been reported. We had a 30 year-old female patient whodeveloped so-called pseudo-Bartter's syndrome as the result of surreptitious self-administration of furosemide for about six years. In this case, calcification of bilateral renal medulla was demonstrated. Such adverse reaction has not been reported to date. Moreover, a total 14 cases of pseudo-Bartter's syndrome reported in Japanese literature is reviewed.
ISSN:0021-5120
1881-123X
DOI:10.2169/internalmedicine1962.20.216