Search Results - "I. Brunner, Hermine"

Distinctions Between Diagnostic and Classification Criteria? by Aggarwal, Rohit, Ringold, Sarah, Khanna, Dinesh, Neogi, Tuhina, Johnson, Sindhu R., Miller, Amy, Brunner, Hermine I., Ogawa, Rikke, Felson, David, Ogdie, Alexis, Aletaha, Daniel, Feldman, Brian M.

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Systemic Juvenile Idiopathic Arthritis–Associated Lung Disease: Characterization and Risk Factors by Schulert, Grant S., Yasin, Shima, Carey, Brenna, Chalk, Claudia, Do, Thuy, Schapiro, Andrew H., Husami, Ammar, Watts, Allen, Brunner, Hermine I., Huggins, Jennifer, Mellins, Elizabeth D., Morgan, Esi M., Ting, Tracy, Trapnell, Bruce C., Wikenheiser‐Brokamp, Kathryn A., Towe, Christopher, Grom, Alexei A.

“…Objective Systemic juvenile idiopathic arthritis (JIA) is associated with a recently recognized, albeit poorly defined and characterized, lung disease (LD)…”
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Randomized Trial of Tocilizumab in Systemic Juvenile Idiopathic Arthritis by De Benedetti, Fabrizio, Brunner, Hermine I, Ruperto, Nicolino, Kenwright, Andrew, Wright, Stephen, Calvo, Inmaculada, Cuttica, Ruben, Ravelli, Angelo, Schneider, Rayfel, Woo, Patricia, Wouters, Carine, Xavier, Ricardo, Zemel, Lawrence, Baildam, Eileen, Burgos-Vargas, Ruben, Dolezalova, Pavla, Garay, Stella M, Merino, Rosa, Joos, Rik, Grom, Alexei, Wulffraat, Nico, Zuber, Zbigniew, Zulian, Francesco, Lovell, Daniel, Martini, Alberto

“…In a randomized trial involving children with severe systemic juvenile idiopathic arthritis, the anti–interleukin-6 receptor antibody tocilizumab was effective…”
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Pediatric Lupus—Are There Differences in Presentation, Genetics, Response to Therapy, and Damage Accrual Compared with Adult Lupus? by Mina, Rina, MD, Brunner, Hermine I., MD

“…Some complement deficiencies predispose to systemic lupus erythematosus (SLE) early in life. Currently, there are no known unique physiologic or genetic…”
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Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans for Juvenile Idiopathic Arthritis–Associated and Idiopathic Chronic Anterior Uveitis by Angeles‐Han, Sheila T., Lo, Mindy S., Henderson, Lauren A., Lerman, Melissa A., Abramson, Leslie, Cooper, Ashley M., Parsa, Miriam F., Zemel, Lawrence S., Ronis, Tova, Beukelman, Timothy, Cox, Erika, Sen, H. Nida, Holland, Gary N., Brunner, Hermine I., Lasky, Andrew, Rabinovich, C. Egla

“…Objective Systemic immunosuppressive treatment of pediatric chronic anterior uveitis (CAU), both juvenile idiopathic arthritis–associated and idiopathic…”
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Urine S100 proteins as potential biomarkers of lupus nephritis activity by Turnier, Jessica L, Fall, Ndate, Thornton, Sherry, Witte, David, Bennett, Michael R, Appenzeller, Simone, Klein-Gitelman, Marisa S, Grom, Alexei A, Brunner, Hermine I

“…Improved, noninvasive biomarkers are needed to accurately detect lupus nephritis (LN) activity. The purpose of this study was to evaluate five S100 proteins…”
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Revisiting Childhood-Onset Systemic Lupus Erythematosus by Avar-Aydın, Pınar Özge, I Brunner, Hermine

“…Childhood-onset systemic lupus erythematosus (cSLE) is a chronic autoimmune disease with a multisystemic involvement diagnosed during childhood. The disease is…”
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Cerebral microvascular and microstructural integrity is regionally altered in patients with systemic lupus erythematosus by DiFrancesco, Mark W, Lee, Gregory, Altaye, Mekibib, Beebe, Dean W, Meyers-Eaton, Jamie, Brunner, Hermine I

“…To measure regional brain microvascular and microstructural changes in childhood-onset SLE (cSLE) using diffusion-weighted imaging (DWI) at multiple b values…”
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Efficacy and Safety of Tocilizumab for Polyarticular‐Course Juvenile Idiopathic Arthritis in the Open‐Label Two‐Year Extension of a Phase III Trial by Brunner, Hermine I., Ruperto, Nicolino, Zuber, Zbigniew, Cuttica, Rubén, Keltsev, Vladimir, Xavier, Ricardo M., Burgos‐Vargas, Ruben, Penades, Inmaculada Calvo, Silverman, Earl D., Espada, Graciela, Zavaler, Manuel Ferrandiz, Kimura, Yukiko, Duarte, Carolina, Job‐Deslandre, Chantal, Joos, Rik, Douglass, Wendy, Wimalasundera, Sunethra, Bharucha, Kamal N., Wells, Chris, Lovell, Daniel J., Martini, Alberto, Benedetti, Fabrizio

“…Objective To report the 2‐year efficacy and safety of tocilizumab (TCZ) in patients with polyarticular‐course juvenile idiopathic arthritis (JIA). Methods…”
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Biomarkers and Updates on Pediatrics Lupus Nephritis by Bennett, Michael, PhD, Brunner, Hermine I., MD, MSc

“…Lupus nephritis is a common complication of systemic lupus erythematosus in children and adolescents. This article reviews the clinical relevance of lupus…”
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Urine biomarkers of chronic kidney damage and renal functional decline in childhood-onset systemic lupus erythematosus by Brunner, Hermine I., Gulati, Gaurav, Klein-Gitelman, Marisa S., Rouster-Stevens, Kelly A., Tucker, Lori, Ardoin, Stacey P., Onel, Karen B., Mainville, Rylie, Turnier, Jessica, Aydin, Pinar Ozge Avar, Witte, David, Huang, Bin, Bennett, Michael R., Devarajan, Prasad

“…Objectives To delineate urine biomarkers that reflect kidney structural damage and predict renal functional decline in pediatric lupus nephritis (LN). Methods…”
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Prevalence of co-existing autoimmune disease in juvenile idiopathic arthritis: a cross-sectional study by Simon, Teresa A, Harikrishnan, Gowri Priya, Kawabata, Hugh, Singhal, Sanket, Brunner, Hermine I, Lovell, Daniel J

“…Many autoimmune diseases share common pathogenic mechanisms, cytokine pathways and systemic inflammatory cascades; however, large studies quantifying the…”
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The use of S100 proteins testing in juvenile idiopathic arthritis and autoinflammatory diseases in a pediatric clinical setting: a retrospective analysis by Aljaberi, Najla, Tronconi, Elena, Schulert, Grant, Grom, Alexei A, Lovell, Daniel J, Huggins, Jennifer L, Henrickson, Michael, Brunner, Hermine I

“…Serum phagocyte-derived alarmins S100A8/9 and S100A12 are considered useful for the assessment of inflammatory diseases. Our study evaluated the use of S100…”
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Tocilizumab may slow radiographic progression in patients with systemic or polyarticular-course juvenile idiopathic arthritis: post hoc radiographic analysis from two randomized controlled trials by Malattia, Clara, Ruperto, Nicolino, Pederzoli, Silvia, Palmisani, Elena, Pistorio, Angela, Wouters, Carine, Dolezalova, Pavla, Flato, Berit, Garay, Stella, Giancane, Gabriella, Wells, Chris, Douglass, Wendy, Brunner, Hermine I, De Benedetti, Fabrizio, Ravelli, Angelo

“…Few clinical trials have investigated the prevention of radiographic progression in children with juvenile idiopathic arthritis treated with antirheumatic…”
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Cross-cultural adaptation and initial validation of the Brazilian-Portuguese version of the pediatric automated neuropsychological assessment metrics by de Amorim, Jaqueline Cristina, Kishimoto, Simone Thiemi, Elorza, Cibele Longobardi Cutinhola, Cavaletti, Flávia Alegretti, Marini, Roberto, Silva, Clovis Artur, Saad-Magalhães, Claudia, Fernandes, Paula Teixeira, Brunner, Hermine I, Appenzeller, Simone

“…Automated neuropsychiatric batteries have been used in research and clinical practice, including for chronic diseases, such as Systemic Lupus Erythematosus…”
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Pharmacokinetic and safety profile of tofacitinib in children with polyarticular course juvenile idiopathic arthritis: results of a phase 1, open-label, multicenter study by Ruperto, Nicolino, Brunner, Hermine I, Zuber, Zbigniew, Tzaribachev, Nikolay, Kingsbury, Daniel J, Foeldvari, Ivan, Horneff, Gerd, Smolewska, Elzbieta, Vehe, Richard K, Hazra, Anasuya, Wang, Rong, Mebus, Charles A, Alvey, Christine, Lamba, Manisha, Krishnaswami, Sriram, Stock, Thomas C, Wang, Min, Suehiro, Ricardo, Martini, Alberto, Lovell, Daniel J

“…Juvenile idiopathic arthritis (JIA) is the most common pediatric rheumatic disease and a leading cause of childhood disability. The objective of this study was…”
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Autoantibodies to Dense Fine Speckles in Pediatric Diseases and Controls by Schmeling, Heinrike, Mahler, Michael, Levy, Deborah M, Moore, Katharine, Stevens, Anne M, Wick, James, McMillan, Jacob D, Horneff, Gerd, Assassi, Shervin, Charles, Julio, Salazar, Gloria, Mayes, Maureen D, Silverman, Earl D, Klien-Gitelman, Marissa, Lee, Tzelan, Brunner, Hermine I, Reed, Ann M, Fritzler, Marvin J

“…Autoantibodies to the dense fine speckled 70 kDa antigen (DFS70) are reported to be more common in individuals who do not have an antinuclear antibody…”
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Pediatric SLE—towards a comprehensive management plan by Brunner, Hermine I., Huggins, Jennifer, Klein-Gitelman, Marisa S.

“…In this Review, the authors describe the marked differences in clinical presentation, prognosis, disease assessment and treatment options that exist between…”
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Stability of novel urinary biomarkers used for lupus nephritis by Cody, Ellen M, Rose, James E, Huang, Bin, Qiu, Tingting, Brunner, Hermine I, Devarajan, Prasad

“…The Renal Activity Index for Lupus (RAIL) is a composite score of six urinary biomarkers (neutrophil gelatinase-associated lipocalin (NGAL), monocyte…”
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PK/PD Study of Mycophenolate Mofetil in Children With Systemic Lupus Erythematosus to Inform Model-Based Precision Dosing by Chen, Yewei, Sun, Li, Xu, Hong, Dong, Min, Mizuno, Tomoyuki, Vinks, Alexander A, Brunner, Hermine I, Li, Yifan, Li, Zhiping

“…To evaluate the mycophenolic acid [MPA, the active form of mycophenolate mofetil (MMF)] pharmacokinetic parameters in relation to clinical response to identify…”
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