Search Results - "I-Ting Lee"

Empagliflozin Attenuates Myocardial Sodium and Calcium Dysregulation and Reverses Cardiac Remodeling in Streptozotocin-Induced Diabetic Rats by Lee, Ting-I, Chen, Yao-Chang, Lin, Yung-Kuo, Chung, Cheng-Chih, Lu, Yen-Yu, Kao, Yu-Hsun, Chen, Yi-Jen

“…Diabetes mellitus (DM) has significant effects on cardiac calcium (Ca ) and sodium (Na⁺) regulation. Clinical studies have shown that empagliflozin…”
Get full text

The influence of diabetes, glycemic control, and diabetes-related comorbidities on pulmonary tuberculosis by Chiang, Chen Yuan, Bai, Kuan Jen, Lin, Hsien Ho, Chien, Shun Tien, Lee, Jen Jyh, Enarson, Donald A, Lee, Ting-I, Yu, Ming-Chih

“…To assess the influence of diabetes mellitus (DM), glycemic control, and diabetes-related comorbidities on manifestations and outcome of treatment of pulmonary…”
Get full text

Therapeutic potential of vitamin D in AGE/RAGE-related cardiovascular diseases by Lee, Ting-Wei, Kao, Yu-Hsun, Chen, Yi-Jen, Chao, Tze-Fan, Lee, Ting-I

“…Cardiovascular diseases (CVDs) are among the leading threats to human health. The advanced glycation end product (AGE) and receptor for AGE (RAGE) signaling…”
Get full text

PAUSE: principled feature attribution for unsupervised gene expression analysis by Janizek, Joseph D, Spiro, Anna, Celik, Safiye, Blue, Ben W, Russell, John C, Lee, Ting-I, Kaeberlin, Matt, Lee, Su-In

“…As interest in using unsupervised deep learning models to analyze gene expression data has grown, an increasing number of methods have been developed to make…”
Get full text

Customized planning of the visible maxillary arch width in harmony with interparopia width and smile width for female facial aesthetics by Yang, Xianrui, Justus, Roberto, Li, Bin, Xue, Chaoran, Lee, I‐Ting (David), Guo, Yongwen, Bai, Ding, Han, Xianglong, Xu, Hui

“…Background The visible maxillary arch width (VAW) is an important aesthetic‐determining feature. To date, there is no well‐established methodology to determine…”
Get full text

Effect of antidiabetic drugs on the risk of atrial fibrillation: mechanistic insights from clinical evidence and translational studies by Lee, Ting-Wei, Lee, Ting-I., Lin, Yung-Kuo, Chen, Yao-Chang, Kao, Yu-Hsun, Chen, Yi-Jen

“…Diabetes mellitus (DM) is an independent risk factor for atrial fibrillation (AF), which is the most common sustained arrhythmia and is associated with…”
Get full text

Social Media-Delivered Patient Education to Enhance Self-management and Attitudes of Patients with Type 2 Diabetes During the COVID-19 Pandemic: Randomized Controlled Trial by Leong, Cheng Man, Lee, Ting-I, Chien, Yu-Mei, Kuo, Li-Na, Kuo, Yu-Feng, Chen, Hsiang-Yin

“…The use of mobile health technologies has been necessary to deliver patient education to patients with diabetes during the COVID-19 pandemic. This open-label…”
Get full text

Ketogenic Diet Regulates Cardiac Remodeling and Calcium Homeostasis in Diabetic Rat Cardiomyopathy by Lee, Ting-I, Trang, Nguyen Ngoc, Lee, Ting-Wei, Higa, Satoshi, Kao, Yu-Hsun, Chen, Yao-Chang, Chen, Yi-Jen

“…A ketogenic diet (KD) might alleviate patients with diabetic cardiomyopathy. However, the underlying mechanism remains unclear. Myocardial function and…”
Get full text

Aging Modulates the Substrate and Triggers Remodeling in Atrial Fibrillation by Lin, Yung-Kuo, Chen, Yi-Ann, Lee, Ting-I, Chen, Yao-Chang, Chen, Shih-Ann, Chen, Yi-Jen

“…Aging plays a critical role in the genesis of atrial fibrillation (AF) and also increases the risks of cardiac dysfunction and stroke in AF patients. AF is…”
Get full text

Fibroblast Growth Factor 23 Stimulates Cardiac Fibroblast Activity through Phospholipase C-Mediated Calcium Signaling by Lee, Ting-Wei, Chung, Cheng-Chih, Lee, Ting-I, Lin, Yung-Kuo, Kao, Yu-Hsun, Chen, Yi-Jen

“…Fibroblast growth factor (FGF)-23 induces hypertrophy and calcium (Ca ) dysregulation in cardiomyocytes, leading to cardiac arrhythmia and heart failure…”
Get full text

A Two-Stage MCDM Model for Exploring the Influential Relationships of Sustainable Sports Tourism Criteria in Taichung City by Yang, Jen-Jen, Chuang, Yen-Ching, Lo, Huai-Wei, Lee, Ting-I

“…Many countries advocate sports for all to cultivate people's interest in sports. In cities, cross-industry alliances between sports and tourism are one of the…”
Get full text

Vascular endothelial growth factor enhances profibrotic activities through modulation of calcium homeostasis in human atrial fibroblasts by Chung, Cheng-Chih, Lin, Yung-Kuo, Chen, Yao-Chang, Kao, Yu-Hsun, Lee, Ting-I, Chen, Yi-Jen

“…Vascular endothelial growth factor (VEGF), a pivotal activator of angiogenesis and calcium (Ca2+) signaling in endothelial cells, was shown to increase…”
Get full text

PPARs modulate cardiac metabolism and mitochondrial function in diabetes by Lee, Ting-Wei, Bai, Kuan-Jen, Lee, Ting-I, Chao, Tze-Fan, Kao, Yu-Hsun, Chen, Yi-Jen

“…Diabetic cardiomyopathy is a major complication of diabetes mellitus (DM). Currently, effective treatments for diabetic cardiomyopathy are limited. The…”
Get full text

Galectin‐3 enhances atrial remodelling and arrhythmogenesis through CD98 signalling by Cheng, Wan‐Li, Chen, Yao‐Chang, Li, Shao‐Jung, Lee, Ting‐I, Lee, Ting‐Wei, Higa, Satoshi, Chung, Cheng‐Chih, Kao, Yu‐Hsun, Chen, Shih‐Ann, Chen, Yi‐Jen

“…Aim Galectin‐3 (Gal‐3) is a biomarker of atrial fibrillation (AF) that mediates atrial inflammation. CD98 is the membrane surface receptor for Gal‐3…”
Get full text

Empagliflozin and Liraglutide Differentially Modulate Cardiac Metabolism in Diabetic Cardiomyopathy in Rats by Trang, Nguyen Ngoc, Chung, Cheng-Chih, Lee, Ting-Wei, Cheng, Wan-Li, Kao, Yu-Hsun, Huang, Shih-Yu, Lee, Ting-I, Chen, Yi-Jen

“…Glucagon-like peptide 1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2is) are antihyperglycemic agents with cardioprotective…”
Get full text

Contribution of buried distal amino acid residues in horse liver alcohol dehydrogenase to structure and catalysis by Shanmuganatham, Karthik K., Wallace, Rachel S., Ting‐I Lee, Ann, Plapp, Bryce V.

“…The dynamics of enzyme catalysis range from the slow time scale (∼ms) for substrate binding and conformational changes to the fast time (∼ps) scale for…”
Get full text

WWOX Phosphorylation, Signaling, and Role in Neurodegeneration by Liu, Chan-Chuan, Ho, Pei-Chuan, Lee, I-Ting, Chen, Yu-An, Chu, Chun-Hsien, Teng, Chih-Chuan, Wu, Sheng-Nan, Sze, Chun-I, Chiang, Ming-Fu, Chang, Nan-Shan

“…Homozygous null mutation of tumor suppressor gene leads to severe neural diseases, metabolic disorders and early death in the newborns of humans, mice and…”
Get full text

Activation of Class I histone deacetylases contributes to mitochondrial dysfunction in cardiomyocytes with altered complex activities by Lkhagva, Baigalmaa, Kao, Yu-Hsun, Lee, Ting-I, Lee, Ting-Wei, Cheng, Wan-Li, Chen, Yi-Jen

“…Histone deacetylases (HDACs) play vital roles in the pathophysiology of heart failure, which is associated with mitochondrial dysfunction. Tumor necrosis…”
Get full text

Sodium hydrosulphide restores tumour necrosis factor‐α‐induced mitochondrial dysfunction and metabolic dysregulation in HL‐1 cells by Lee, Ting‐I, Kao, Yu‐Hsun, Baigalmaa, Lkhagva, Lee, Ting‐Wei, Lu, Yen‐Yu, Chen, Yao‐Chang, Chao, Tze‐Fan, Chen, Yi‐Jen

“…Tumour necrosis factor (TNF)‐α induces cardiac metabolic disorder and mitochondrial dysfunction. Hydrogen sulphide (H2S) contains anti‐inflammatory and…”
Get full text

Lifestyle factors associated with muscle quality in community‐dwelling older people with type 2 diabetes in Japan and Taiwan: a cross‐sectional study by Yamaguchi, Yuko, Greiner, Chieko, Lee, Shu‐Chun, Ryuno, Hirochika, Yen, Hsin‐Yen, Lin, Chiou‐Fen, Lee, Ting‐I, Lee, Pi‐Hsia

“…Background Type 2 diabetes mellitus (T2DM), common in older people, is an important reason for muscle loss in Japanese and Taiwanese populations. However,…”
Get full text