Search Results - "I-Huan Wu"

Inhibiting Glycosphingolipid Synthesis Improves Glycemic Control and Insulin Sensitivity in Animal Models of Type 2 Diabetes by HONGMEI ZHAO, PRZYBYLSKA, Malgorzata, WU, I-Huan, JINHUA ZHANG, SIEGEL, Craig, KOMARNITSKY, Svetlana, YEW, Nelson S, CHENG, Seng H

“…Inhibiting Glycosphingolipid Synthesis Improves Glycemic Control and Insulin Sensitivity in Animal Models of Type 2 Diabetes Hongmei Zhao , Malgorzata…”
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A Mini-Review of the Kinetic Energy Partition Method in Quantum Mechanics by Chen, Yu-Hsin, Wu, I-Huan, Chao, Sheng D.

“…Based on the idea of adiabatic symmetry, we present a novel basis set expansion method—the kinetic energy partition (KEP) method—for solving quantum eigenvalue…”
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Increased Hepatic Insulin Action in Diet-Induced Obese Mice Following Inhibition of Glucosylceramide Synthase by Yew, Nelson S, Zhao, Hongmei, Hong, Eun-Gyoung, Wu, I-Huan, Przybylska, Malgorzata, Siegel, Craig, Shayman, James A, Arbeeny, Cynthia M, Kim, Jason K, Jiang, Canwen, Cheng, Seng H

“…Background: Obesity is characterized by the accumulation of fat in the liver and other tissues, leading to insulin resistance. We have previously shown that a…”
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Independent Human MAP Kinase Signal Transduction Pathways Defined by MEK and MKK Isoforms by Dérijard, Benoit, Raingeaud, Joël, Barrett, Tamera, I-Huan Wu, Han, Jiahuai, Ulevitch, Richard J., Davis, Roger J.

“…Mammalian mitogen-activated protein (MAP) kinases include extracellular signal-regulated protein kinase (ERK), c-Jun amino-terminal kinase (JNK), and p38…”
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Inhibiting glycosphingolipid synthesis ameliorates hepatic steatosis in obese mice by Zhao, Hongmei, Przybylska, Malgorzata, Wu, I‐Huan, Zhang, Jinhua, Maniatis, Panagiotis, Pacheco, Joshua, Piepenhagen, Peter, Copeland, Diane, Arbeeny, Cynthia, Shayman, James A., Aerts, Johannes M., Jiang, Canwen, Cheng, Seng H., Yew, Nelson S.

“…Steatosis in the liver is a common feature of obesity and type 2 diabetes and the precursor to the development of nonalcoholic steatohepatitis (NASH),…”
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Reduced Inflammatory Response to Plasmid DNA Vectors by Elimination and Inhibition of Immunostimulatory CpG Motifs by Yew, Nelson S., Zhao, Hongmei, Wu, I-Huan, Song, Antonius, Tousignant, Jennifer D., Przybylska, Malgorzata, Cheng, Seng H.

“…An inflammatory response is invariably associated with administration of gene transfer complexes composed of cationic lipids and plasmid DNA (pDNA). In the…”
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An Osmosensing Signal Transduction Pathway in Mammalian Cells by Galcheva-Gargova, Zoya, Dérijard, Benoit, I-Huan Wu, Davis, Roger J.

“…The osmotic balance between the cytoplasmic and extracellular compartments of cells is critical for the control of cell volume. A mammalian protein kinase,…”
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A Conserved p38 Mitogen-Activated Protein Kinase Pathway Regulates Drosophila Immunity Gene Expression by Han, Zhiqiang Stanley, Enslen, Hervé, Hu, Xiaodi, Meng, Xiangjun, Wu, I-Huan, Barrett, Tamera, Davis, Roger J., Ip, Y. Tony

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Binding of Zinc Finger Protein ZPR1 to the Epidermal Growth Factor Receptor by Galcheva-Gargova, Zoya, Konstantinov, Konstantin N., I-Huan Wu, Klier, F. George, Barrett, Tamera, Davis, Roger J.

“…ZPR1 is a zinc finger protein that binds to the cytoplasmic tyrosine kinase domain of the epidermal growth factor receptor (EGFR). Deletion analysis…”
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Partial correction of the α-galactosidase A deficiency and reduction of glycolipid storage in Fabry mice using synthetic vectors by Przybylska, Malgorzata, Wu, I-Huan, Zhao, Hongmei, Ziegler, Robin J., Tousignant, Jennifer D., Desnick, Robert J., Scheule, Ronald K., Cheng, Seng H., Yew, Nelson S.

“…Background Fabry disease is a recessive, X‐linked disorder caused by a deficiency of the lysosomal enzyme α‐galactosidase A, leading to an accumulation of the…”
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CpG-Depleted Plasmid DNA Vectors with Enhanced Safety and Long-Term Gene Expression in Vivo by Yew, Nelson S., Zhao, Hongmei, Przybylska, Malgorzata, Wu, I-Huan, Tousignant, Jennifer D., Scheule, Ronald K., Cheng, Seng H.

“…Systemic delivery of cationic lipid–plasmid DNA (pDNA) complexes induces an acute inflammatory response with adverse hematologic changes and liver damage…”
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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain by Dérijard, B, Hibi, M, Wu, I H, Barrett, T, Su, B, Deng, T, Karin, M, Davis, R J

“…The ultraviolet (UV) response of mammalian cells is characterized by a rapid and selective increase in gene expression mediated by AP-1 and NF-kappa B. The…”
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AAV Vector-Mediated Correction of Brain Pathology in a Mouse Model of Niemann–Pick A Disease by Passini, Marco A., Macauley, Shannon L., Huff, Michael R., Taksir, Tatyana V., Bu, Jie, Wu, I-Huan, Piepenhagen, Peter A., Dodge, James C., Shihabuddin, Lamya S., O'Riordan, Catherine R., Schuchman, Edward H., Stewart, Gregory R.

“…Niemann–Pick A disease (NPA) is a fatal lysosomal storage disorder caused by a deficiency in acid sphingomyelinase (ASM) activity. The lack of functional ASM…”
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Protection from ultraviolet irradiation by melanin of mosquitocidal activity of Bacillus thuringiensis var. israelensis by Liu, Y T, Sui, M J, Ji, D D, Wu, I H, Chou, C C, Chen, C C

“…A process for production, isolation, and purification of melanin produced by the fermentation of Streptomyces lividans 66 harboring a recombinant plasmid…”
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Systemic delivery of a Peptide-linked morpholino oligonucleotide neutralizes mutant RNA toxicity in a mouse model of myotonic dystrophy by Leger, Andrew J, Mosquea, Leocadia M, Clayton, Nicholas P, Wu, I-Huan, Weeden, Timothy, Nelson, Carol A, Phillips, Lucy, Roberts, Errin, Piepenhagen, Peter A, Cheng, Seng H, Wentworth, Bruce M

“…Expansions of CUG trinucleotide sequences in RNA transcripts provide the basis for toxic RNA gain-of-function that leads to detrimental changes in RNA…”
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Preparation and properties of Eucommia ulmoides gum/polylactic acid shape memory thermoplastic vulcanizates by LI Jia-huan, WU Shao-wei, HAN Li-shuo, LI Dong-han, LI Long, KANG Hai-lan, FANG Qing-hong

“…Bio-based Eucommia ulmoides gum (EUG) and polylactic acid (PLA) were used to prepare thermoplastic vulcanizates (EUG/PLA TPV) with shape memory property by…”
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Partial correction of the ±-galactosidase A deficiency and reduction of glycolipid storage in Fabry mice using synthetic vectors by Przybylska, Malgorzata, I-Huan, Wu, Zhao, Hongmei, Ziegler, Robin J, Tousignant, Jennifer D, Desnick, Robert J, Scheule, Ronald K, Cheng, Seng H, Yew, Nelson S

“…Fabry disease is a recessive, X-linked disorder caused by a deficiency of the lysosomal enzyme ±-galactosidase A, leading to an accumulation of the…”
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Independent human MAP kinse signal transduction pathways defined by MEK and MKK isoforms by DERIJARD, B, RAINGEAUD, J, BARRETT, T, I-HUAN WU, JIAHUAI HAN, ULEVITCH, R. J, DAVIS, R. J

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Genesis of the Zhaokalong Fe-Cu Polymetallic Deposit at Yushu, China： Evidence from Ore Geochemistry and Fluid Inclusions by Huan, LI, Xiaoshuang, XI, Chengming, WU, WATANABE, Koichiro

“…The ore types of the Zhaokalong Fe-Cu deposit are divided into two categories： sulfide-type and oxide-type. The sulfide-type ore include siderite ore,…”
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Interference with ADAM17 inhibits proliferation of human cervical cancer cell line HeLa by ZHANG Chun-li, QI Jie-hua, HUAN Yu, WU Shou-le, CAI Xu-shan

“…Objective To investigate the effect of ADAM17 on proliferation of cervical cancer cells in vitro and its mechanism. Methods The specific shRNA against ADAM17…”
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