Search Results - "Işık, Mesut"

The Binding Mechanisms and Inhibitory Effect of Intravenous Anesthetics on AChE In Vitro and In Vivo: Kinetic Analysis and Molecular Docking by Işık, Mesut

“…Inhibitors of acetylcholinesterase (AChE), which have an important role in the prevention of excessive AChE activity and β-amyloid (Aβ) formation are widely…”
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Kur’an’a Göre Şükrün İnsan Hayatındaki Önemi by IŞIK, Mesut

“…Allah’a kulluk vazifesini yerine getirmek üzere yaratılan insanın dünya ve âhirette saadetini temin edecek değer ve erdemlerden biri de huzur ve şifa kaynağı…”
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Phytochemical Analysis of Paliurus spina-christi Fruit and Its Effects on Oxidative Stress and Antioxidant Enzymes in Streptozotocin-Induced Diabetic Rats by Takım, Kasım, Işık, Mesut

“…Oxidative stress can play an important role in the autoxidation of glucose, glycation of proteins and activation of polyol metabolism, and the development of…”
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High Stability of Immobilized Acetylcholinesterase on Chitosan Beads by Işık, Mesut

“…The enzymes are unstable and have a short lifetime; this causes a decrease in the number of enzyme usage and increases the cost. In the study, the…”
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Explainable artificial intelligence in the design of selective carbonic anhydrase I‐II inhibitors via molecular fingerprinting by Kırboğa, Kevser Kübra, Işık, Mesut

“…Inhibiting the enzymes carbonic anhydrase I (CA I) and carbonic anhydrase II (CA II) presents a potential avenue for addressing nervous system ailments such as…”
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COVID-19 ve sirkadiyen ritim by Güzel Özdemir,Pınar, Işık,Mesut

“…Sayın Editör, Yeni tip koronavirüs hastalığı (COVID-19) Ocak 2020’de Çin'de başlamış olup hızla tüm dünyaya yayılarak pandemi olarak kabul edilmiştir…”
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The mediating effect of attachment insecurity on circadian consequences of childhood trauma by Işik, Mesut, Kirli, Umut

“…Circadian preferences have been associated with mental health as well as social and physical health in recent years. However, factors associated with circadian…”
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The impact of some phenolic compounds on serum acetylcholinesterase: kinetic analysis of an enzyme/inhibitor interaction and molecular docking study by Işık, Mesut, Beydemir, Şükrü

“…In the treatment of Alzheimer's disease (AD), it is important to develop alternative cholinesterase inhibitors with antioxidant properties that will reduce…”
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An approach to clarify the effect mechanism of glyphosate on body malformations during embryonic development of zebrafish (Daino rerio) by Sulukan, Ekrem, Köktürk, Mine, Ceylan, Hamid, Beydemir, Şükrü, Işik, Mesut, Atamanalp, Muhammed, Ceyhun, Saltuk Buğrahan

“…In this study, it has been investigated that the effects of glyphosate, which is a herbicide within organophosphate and unselective widely used in agriculture…”
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The relationship between overactive bladder and attachment: A preliminary study by IŞIK, Mesut, DEMİR, Murat

“…Aim There are strong relationships between overactive bladder (OAB) and psychological factors. The aim of this study was to examine the relationship between…”
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Mannich reaction derived novel boron complexes with amine-bis(phenolate) ligands: Synthesis, spectroscopy and in vitro/in silico biological studies by Kilic, Ahmet, Beyazsakal, Levent, Işık, Mesut, Türkeş, Cüneyt, Necip, Adem, Takım, Kasım, Beydemir, Şükrü

“…•The new amine-bis(phenolate) boron complexes were prepared and fully characterized.•The various spectroscopic methods were used for characterization of…”
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Prevalence of Posttraumatic Stress Disorder and Depression among the Individuals within Faculty of Dentistry, who Experienced Earthquake and who did not, and the Relation with Temporomandibular Joint Disorders by Eroğlu, Cennet Neslihan, Keskin Tunç, Serap, Işık, Mesut, Elasan, Sadi

“…INTRODUCTION: The present study aimed to investigate the prevalence of Posttraumatic Stress Disorder (PTSD)-depression among the volunteers within the Faculty…”
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AChE mRNA expression as a possible novel biomarker for the diagnosis of coronary artery disease and Alzheimer's disease, and its association with oxidative stress by Işık, Mesut, Beydemir, Şükrü

“…Oxidative metabolic reactions and their by products have played a role in coronary artery disease (CAD) and Alzheimer's disease (AD) pathogenesis. This study…”
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Benzenesulfonamide derivatives as potent acetylcholinesterase, α-glycosidase, and glutathione S-transferase inhibitors: biological evaluation and molecular docking studies by Taslimi, Parham, Işık, Mesut, Türkan, Fikret, Durgun, Mustafa, Türkeş, Cüneyt, Gülçin, İlhami, Beydemir, Şükrü

“…Sulfonamide derivatives exhibit a wide biological activity and can function as potential medical molecules in the development of a drug. Studies have reported…”
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Novel inhibitors with sulfamethazine backbone: synthesis and biological study of multi-target cholinesterases and α-glucosidase inhibitors by Türkeş, Cüneyt, Akocak, Suleyman, Işık, Mesut, Lolak, Nebih, Taslimi, Parham, Durgun, Mustafa, Gülçin, İlhami, Budak, Yakup, Beydemir, Şükrü

“…The underlying cause of many metabolic diseases is abnormal changes in enzyme activity in metabolism. Inhibition of metabolic enzymes such as cholinesterases…”
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Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases by Durgun, Mustafa, Türkeş, Cüneyt, Işık, Mesut, Demir, Yeliz, Saklı, Ali, Kuru, Ali, Güzel, Abdussamat, Beydemir, Şükrü, Akocak, Suleyman, Osman, Sameh M., AlOthman, Zeid, Supuran, Claudiu T.

“…Sulphonamides are biologically important compounds with low toxicity, many bioactivities and cost-effectiveness. Eight sulphonamide derivatives were…”
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Conducting polymer‐based electrochemical biosensor for the detection of acetylthiocholine and pesticide via acetylcholinesterase by Akdag, Abdurrahman, Işık, Mesut, Göktaş, Hasan

“…A voltammetric biosensor for acetylthiocholine (ATCh) and paraoxon detection was successfully developed. To achieve this goal, polypyrrole (PPy) was…”
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Molecular docking and investigation of 4-(benzylideneamino)- and 4-(benzylamino)-benzenesulfonamide derivatives as potent AChE inhibitors by Işık, Mesut, Demir, Yeliz, Durgun, Mustafa, Türkeş, Cüneyt, Necip, Adem, Beydemir, Şükrü

“…The discovery of acetylcholinesterase inhibitors is important for the treatment of Alzheimer’s disease (AD), known as the most common type of dementia. Due to…”
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Novel bis-ureido-substituted sulfaguanidines and sulfisoxazoles as carbonic anhydrase and acetylcholinesterase inhibitors by Lolak, Nebih, Akocak, Süleyman, Durgun, Mustafa, Duran, Hatice Esra, Necip, Adem, Türkeş, Cüneyt, Işık, Mesut, Beydemir, Şükrü

“…To discover alternative substances to compounds used to treat many diseases, especially treating Alzheimer’s disease (AD) and Parkinson’s disease targeting…”
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Benzenesulfonamide derivatives containing imine and amine groups: Inhibition on human paraoxonase and molecular docking studies by Işık, Mesut, Beydemir, Şükrü, Demir, Yeliz, Durgun, Mustafa, Türkeş, Cüneyt, Nasır, Abdul, Necip, Adem, Akkuş, Musa

“…Sulfonamides known as inhibitors of many metabolic enzymes have been widely used as antimicrobial drugs for a long time. In the present study, we investigated…”
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