Search Results - "Hyunju Lee"
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1
Prediction of Alzheimer’s disease using blood gene expression data
Published in Scientific reports (26-02-2020)“…Identification of AD (Alzheimer’s disease)-related genes obtained from blood samples is crucial for early AD diagnosis. We used three public datasets, ADNI,…”
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2
Biomedical named entity recognition using deep neural networks with contextual information
Published in BMC bioinformatics (27-12-2019)“…In biomedical text mining, named entity recognition (NER) is an important task used to extract information from biomedical articles. Previously proposed…”
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3
Identifying disease-gene associations using a convolutional neural network-based model by embedding a biological knowledge graph with entity descriptions
Published in PloS one (15-10-2021)“…Understanding the role of genes in human disease is of high importance. However, identifying genes associated with human diseases requires laborious…”
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4
Crossfeat: a transformer-based cross-feature learning model for predicting drug side effect frequency
Published in BMC bioinformatics (08-10-2024)“…Safe drug treatment requires an understanding of the potential side effects. Identifying the frequency of drug side effects can reduce the risks associated…”
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DeepPIG: deep neural network architecture with pairwise connected layers and stochastic gates using knockoff frameworks for feature selection
Published in Scientific reports (06-07-2024)“…Selecting relevant feature subsets is essential for machine learning applications. Among the feature selection techniques, the knockoff filter procedure…”
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6
HUBO and QUBO models for prime factorization
Published in Scientific reports (21-06-2023)“…The security of the RSA cryptosystem is based on the difficulty of factoring a large number N into prime numbers p and q satisfying N = p × q . This paper…”
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7
Molecular data representation based on gene embeddings for cancer drug response prediction
Published in Scientific reports (11-12-2023)“…Cancer drug response prediction is a crucial task in precision medicine, but existing models have limitations in effectively representing molecular profiles of…”
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Joint triplet loss with semi-hard constraint for data augmentation and disease prediction using gene expression data
Published in Scientific reports (24-10-2023)“…The accurate prediction of patients with complex diseases, such as Alzheimer’s disease (AD), as well as disease stages, including early- and late-stage cancer,…”
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9
Integrative reconstruction of cancer genome karyotypes using InfoGenomeR
Published in Nature communications (29-04-2021)“…Annotation of structural variations (SVs) and base-level karyotyping in cancer cells remains challenging. Here, we present Integrative Framework for Genome…”
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10
A method for named entity normalization in biomedical articles: application to diseases and plants
Published in BMC bioinformatics (13-10-2017)“…In biomedical articles, a named entity recognition (NER) technique that identifies entity names from texts is an important element for extracting biological…”
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11
HIDTI: integration of heterogeneous information to predict drug-target interactions
Published in Scientific reports (08-03-2022)“…Identification of drug-target interactions (DTIs) plays a crucial role in drug development. Traditional laboratory-based DTI discovery is generally costly and…”
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12
Impact of Public Health Interventions on Seasonal Influenza Activity During the COVID-19 Outbreak in Korea
Published in Clinical infectious diseases (01-07-2021)“…Abstract Background Coronavirus disease 2019 (COVID-19) was introduced in Korea early with a large outbreak in mid-February. We reviewed the public health…”
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13
Super.FELT: supervised feature extraction learning using triplet loss for drug response prediction with multi-omics data
Published in BMC bioinformatics (25-05-2021)“…Predicting the drug response of a patient is important for precision oncology. In recent studies, multi-omics data have been used to improve the prediction…”
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14
Prediction of the 3D cancer genome from whole-genome sequencing using InfoHiC
Published in Molecular systems biology (25-09-2024)“…The 3D genome prediction in cancer is crucial for uncovering the impact of structural variations (SVs) on tumorigenesis, especially when they are present in…”
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15
PINNet: a deep neural network with pathway prior knowledge for Alzheimer's disease
Published in Frontiers in aging neuroscience (14-07-2023)“…Identification of Alzheimer's Disease (AD)-related transcriptomic signatures from blood is important for early diagnosis of the disease. Deep learning…”
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16
SDGCCA: Supervised Deep Generalized Canonical Correlation Analysis for Multi-Omics Integration
Published in Journal of computational biology (01-08-2022)“…Integration of multi-omics data provides opportunities for revealing biological mechanisms related to certain phenotypes. We propose a novel method of…”
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17
A computational approach to identifying gene-microRNA modules in cancer
Published in PLoS computational biology (01-01-2015)“…MicroRNAs (miRNAs) play key roles in the initiation and progression of various cancers by regulating genes. Regulatory interactions between genes and miRNAs…”
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18
Meta-analysis of pain relief effects by laser irradiation on joint areas
Published in Photomedicine and laser surgery (01-08-2012)“…Laser therapy has been proposed as a physical therapy for musculoskeletal disorders and has attained popularity because no side effects have been reported…”
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19
A Study on Optimization of Noise Reduction of Powered Vehicle Seat Movement Using Brushless Direct-Current Motor
Published in Sensors (Basel, Switzerland) (23-02-2023)“…In this paper, an optimal design model was developed to reduce noise and secure the torque performance of a brushless direct-current motor used in the seat of…”
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20
Cancer-Stimulated CAFs Enhance Monocyte Differentiation and Protumoral TAM Activation via IL6 and GM-CSF Secretion
Published in Clinical cancer research (01-11-2018)“…Abstract Purpose: M2-type TAMs are increasingly implicated as a crucial factor promoting metastasis. Numerous cell types dictate monocyte differentiation into…”
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