Search Results - "Hyun, Min Young"

Deep insight into neutrophil trafficking in various organs by Hyun, Young‐Min, Hong, Chang‐Won

“…Review on neutrophil migration from blood vessels, and the spatiotemporal regulation of the overall immune response. Neutrophils are professional phagocytes…”
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Particulate matter-induced senescence of skin keratinocytes involves oxidative stress-dependent epigenetic modifications by Ryu, Yea Seong, Kang, Kyoung Ah, Piao, Mei Jing, Ahn, Mee Jung, Yi, Joo Mi, Bossis, Guillaume, Hyun, Young-Min, Park, Chang Ook, Hyun, Jin Won

“…Ambient air particulate matter (PM) induces senescence in human skin cells. However, the underlying mechanisms remain largely unknown. We investigated how…”
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LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) distinctly regulate neutrophil extravasation through hotspots I and II by Hyun, Young-Min, Choe, Young Ho, Park, Sang A., Kim, Minsoo

“…Precise spatiotemporal regulation of leukocyte extravasation is key for generating an efficient immune response to injury or infection. The integrins…”
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The functional and biological effects of systemic dexamethasone on mice with facial nerve crushing injury by Bae, Seong Hoon, Park, Haeng Ran, Lim, Hyunseo, Kim, Hyo Yeol, Cheon, Taeuk, Jung, Jinsei, Hyun, Young‐Min

“…Background Corticosteroid therapy is commonly recommended for acute facial nerve weakness; however, its effectiveness in treating traumatic nerve injuries…”
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T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells by Kim, Hye-Ran, Mun, YeVin, Lee, Kyung-Sik, Park, Yoo-Jin, Park, Jeong-Su, Park, Jin-Hwa, Jeon, Bu-Nam, Kim, Chang-Hyun, Jun, Youngsoo, Hyun, Young-Min, Kim, Minsoo, Lee, Sang-Myeong, Park, Chul-Seung, Im, Sin-Hyeog, Jun, Chang-Duk

“…Microvilli on T cells have been proposed to survey surfaces of antigen-presenting cells (APC) or facilitate adhesion under flow; however, whether they serve…”
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NLRP3 exacerbates EAE severity through ROS-dependent NET formation in the mouse brain by Byun, Da Jeong, Lee, Jaeho, Ko, Kyungryung, Hyun, Young-Min

“…Neutrophil extracellular trap (NET) has been implicated in the pathology of multiple sclerosis (MS) and experimental autoimmune encephalomyelitis (EAE)…”
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Particulate matter stimulates the NADPH oxidase system via AhR-mediated epigenetic modifications by Kang, Kyoung Ah, Piao, Mei Jing, Fernando, Pincha Devage Sameera Madushan, Herath, Herath Mudiyanselage Udari Lakmini, Yi, Joo Mi, Choi, Yung Hyun, Hyun, Young-Min, Zhang, Kelun, Park, Chang Ook, Hyun, Jin Won

“…Stimulation of human keratinocytes with particulate matter 2.5 (PM2.5) elicits complex signaling events, including a rise in the generation of reactive oxygen…”
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PM2.5 Exposure in the Respiratory System Induces Distinct Inflammatory Signaling in the Lung and the Liver of Mice by Hyun, Young-Min, Cho, Nam Hoon, Kim, Pilhan, Park, Inwon, Park, Sang A, Jeong, Soi, Hyun, Jin Won

“…Fine particulate matter 2.5 (PM2.5) is a harmful air pollutant currently threatening public health. Although many studies have been performed on the general…”
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Particulate matter induces inflammatory cytokine production via activation of NFκB by TLR5-NOX4-ROS signaling in human skin keratinocyte and mouse skin by Ryu, Yea Seong, Kang, Kyoung Ah, Piao, Mei Jing, Ahn, Mee Jung, Yi, Joo Mi, Hyun, Young-Min, Kim, Seo Hyeong, Ko, Min Kyung, Park, Chang Ook, Hyun, Jin Won

“…Particulate matter (PM) increases levels of pro-inflammatory cytokines, but its effects on the skin remain largely unknown. We investigated the signal…”
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Ischemic stroke outcome after promoting CD4+CD25+ Treg cell migration through CCR4 overexpression in a tMCAO animal model by Lee, Seowoo, Kim, Jiwon, You, Je Sung, Hyun, Young-Min, Kim, Jong Youl, Lee, Jong Eun

“…The importance of neuroinflammation during the ischemic stroke has been extensively studied. The role of CD4+CD25+ regulatory T (Treg) cells during the…”
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Investigation of intact mouse cochleae using two‐photon laser scanning microscopy by Bae, Seong Hoon, Kwak, Sang Hyun, Choe, Young Ho, Hyun, Young‐Min, Choi, Jae Young, Jung, Jinsei

“…Objectives The investigation of cochlear hair cells and lateral wall is a time‐consuming and labor‐intensive process. However, it is a mandatory experiment in…”
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Optogenetic control of chemokine receptor signal and T-cell migration by Xu, Yuexin, Hyun, Young-Min, Lim, Kihong, Lee, Hyunwook, Cummings, Ryan J., Gerber, Scott A., Bae, Seyeon, Cho, Thomas Yoonsang, Lord, Edith M., Kim, Minsoo

“…Adoptive cell transfer of ex vivo-generated immune-promoting or tolerogenic T cells to either enhance immunity or promote tolerance in patients has been used…”
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Skin-resident natural killer T cells participate in cutaneous allergic inflammation in atopic dermatitis by Sun, ZhengWang, Kim, Ji Hye, Kim, Seo Hyeong, Kim, Hye Ran, Zhang, KeLun, Pan, Youdong, Ko, Min Kyung, Kim, Bo Mi, Chu, Howard, Lee, Hee Ra, Kim, Hye Li, Kim, Ji Hyung, Fu, Xiujun, Hyun, Young-Min, Yun, Ki Na, Kim, Jin Young, Lee, Dong Won, Song, Seung Yong, Lin, Charles P., Clark, Rachael A., Lee, Kwang Hoon, Kupper, Thomas S., Park, Chang Ook

“…Natural killer T (NKT) cells are unconventional T cells that bridge innate and adaptive immunity. NKT cells have been implicated in the development of atopic…”
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TM4SF19-mediated control of lysosomal activity in macrophages contributes to obesity-induced inflammation and metabolic dysfunction by Choi, Cheoljun, Jeong, Yujin L., Park, Koung-Min, Kim, Minji, Kim, Sangseob, Jo, Honghyun, Lee, Sumin, Kim, Heeseong, Choi, Garam, Choi, Yoon Ha, Seong, Je Kyung, Namgoong, Sik, Chung, Yeonseok, Jung, Young-Suk, Granneman, James G., Hyun, Young-Min, Kim, Jong Kyoung, Lee, Yun-Hee

“…Adipose tissue (AT) adapts to overnutrition in a complex process, wherein specialized immune cells remove and replace dysfunctional and stressed adipocytes…”
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Optimization of the optical transparency of bones by PACT-based passive tissue clearing by Jin, Byung-Ho, Woo, Jiwon, Lee, Mirae, Ku, Seockmo, Moon, Hyung Seok, Ryu, Seung Jun, Hyun, Young-Min, Park, Jeong-Yoon, Kuh, Sung Uk, Cho, Yong Eun

“…Recent developments in tissue clearing methods such as the passive clearing technique (PACT) have allowed three-dimensional analysis of biological structures…”
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Neutrophils Facilitate Prolonged Inflammasome Response in the DAMP-Rich Inflammatory Milieu by Son, Seunghwan, Yoon, Sung-Hyun, Chae, Byeong Jun, Hwang, Inhwa, Shim, Do-Wan, Choe, Young Ho, Hyun, Young-Min, Yu, Je-Wook

“…Aberrant inflammasome activation contributes to various chronic inflammatory diseases; however, pyroptosis of inflammasome-active cells promptly terminates…”
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Neutrophils Return to Bloodstream Through the Brain Blood Vessel After Crosstalk With Microglia During LPS-Induced Neuroinflammation by Kim, Yu Rim, Kim, Young Min, Lee, Jaeho, Park, Joohyun, Lee, Jong Eun, Hyun, Young-Min

“…The circulatory neutrophil and brain tissue-resident microglia are two important immune cells involved in neuroinflammation. Since neutrophils that infiltrate…”
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Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels by Hyun, Young-Min, Sumagin, Ronen, Sarangi, Pranita P, Lomakina, Elena, Overstreet, Michael G, Baker, Christina M, Fowell, Deborah J, Waugh, Richard E, Sarelius, Ingrid H, Kim, Minsoo

“…The efficient trafficking of immune cells into peripheral nonlymphoid tissues is key to enact their protective functions. Despite considerable advances in our…”
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Neutrophils infiltrate into the spiral ligament but not the stria vascularis in the cochlea during lipopolysaccharide-induced inflammation by Bae, Seong Hoon, Yoo, Jee Eun, Choe, Young Ho, Kwak, Sang Hyun, Choi, Jae Young, Jung, Jinsei, Hyun, Young-Min

“…It has been challenging to apply intravital imaging for monitoring the inner ear, as the anatomical location and intricate structure hamper the access of…”
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Inhibition of Pendrin by a small molecule reduces Lipopolysaccharide-induced acute Lung Injury by Lee, Eun Hye, Shin, Mi Hwa, Gi, Mia, Park, Jinhong, Song, Doona, Hyun, Young-Min, Ryu, Ji-Hwan, Seong, Je Kyung, Jeon, Yoon, Han, Gyoonhee, Namkung, Wan, Park, Moo Suk, Choi, Jae Young

“…Rationale: Pendrin is encoded by SLC26A4 and its mutation leads to congenital hearing loss. Additionally, pendrin is up-regulated in inflammatory airway…”
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