Search Results - "Hytönen, Jarkko P"

Aluminum fluoride-18 labeled folate enables in vivo detection of atherosclerotic plaque inflammation by positron emission tomography by Silvola, Johanna M. U., Li, Xiang-Guo, Virta, Jenni, Marjamäki, Päivi, Liljenbäck, Heidi, Hytönen, Jarkko P., Tarkia, Miikka, Saunavaara, Virva, Hurme, Saija, Palani, Senthil, Hakovirta, Harri, Ylä-Herttuala, Seppo, Saukko, Pekka, Chen, Qingshou, Low, Philip S., Knuuti, Juhani, Saraste, Antti, Roivainen, Anne

“…Inflammation plays an important role in the development of atherosclerosis and its complications. Because the folate receptor β (FR-β) is selectively expressed…”
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Synthetic Flavonoid 3,7-Dihydroxy-Isoflav-3-Ene (DHIF) Reduces In-Stent Restenosis in an Atherosclerotic Watanabe Heritable Hyperlipidemic Rabbit Stent Model by Hytönen, Jarkko P, Leppänen, Olli, Taavitsainen, Jouni, Ylä-Herttuala, Seppo

“…Inflammation is a major component of the pathogenesis of atherosclerosis and the formation of in-stent restenosis (ISR). A novel flavonoid, DHIF, attenuates…”
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Biodegradable coronary scaffolds: their future and clinical and technological challenges by Hytönen, Jarkko P, Taavitsainen, Jouni, Tarvainen, Santeri, Ylä-Herttuala, Seppo

“…Abstract Angioplasty and stenting are standard treatment options for both stabile occlusive coronary artery disease and acute myocardial infarctions. Over the…”
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Local adventitial anti-angiogenic gene therapy reduces growth of vasa-vasorum and in-stent restenosis in WHHL rabbits by Hytönen, Jarkko P., Taavitsainen, Jouni, Laitinen, Johannes T.T., Partanen, Anna, Alitalo, Kari, Leppänen, Olli, Ylä-Herttuala, Seppo

“…Antiproliferative drugs in drug eluting stents (DES) are associated with complications due to impaired re-endothelialization. Additionally, adventitial…”
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Ultrasound imaging with bolus delivered contrast agent for the detection of angiogenesis and blood flow irregularities by Korpisalo, Petra, Hytönen, Jarkko P, Laitinen, Johannes T T, Närväinen, Johanna, Rissanen, Tuomas T, Gröhn, Olli H, Ylä-Herttuala, Seppo

“…Highly increased blood flow and vascularity after angiogenic gene therapy have raised concerns of shunting and hemangioma-like blood pool formation that might…”
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Capillary enlargement, not sprouting angiogenesis, determines beneficial therapeutic effects and side effects of angiogenic gene therapy by Korpisalo, Petra, Hytönen, Jarkko P., Laitinen, Johannes T.T., Laidinen, Svetlana, Parviainen, Henna, Karvinen, Henna, Siponen, Jaana, Marjomäki, Varpu, Vajanto, Ismo, Rissanen, Tuomas T., Ylä-Herttuala, Seppo

“…Aims Currently, it is still unclear which mechanisms drive metabolic benefits after angiogenic gene therapy. The side-effect profile of efficient angiogenic…”
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Improved endothelialization of small-diameter ePTFE vascular grafts through growth factor therapy by Hytönen, Jarkko P, Leppänen, Olli, Taavitsainen, Jouni, Korpisalo, Petra, Laidinen, Svetlana, Alitalo, Kari, Wadström, Jonas, Rissanen, Tuomas T, Ylä-Herttuala, Seppo

“…Background Prosthetic vascular grafts in humans characteristically lack confluent endothelialization regardless of the duration of implantation. Use of…”
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Abstract 18166: Increasing Endothelialization of BMS and DES With Intra-arterial AdVEGF-A Gene Therapy in Porcine Coronary Arteries by Hytonen, Jarkko P, Halonen, Paavo, Tarvainen, Santeri, Taavitsainen, Jouni, Kuivanen, Antti, Koistinen, Arto, Laakkonen, Johanna, Hartikainen, Juha, Yla-Herttuala, Seppo

“…We aimed to increase stent endothelialization with gene therapy known to promote endothelial proliferation. In addition, we evaluated OCT and angioscopy…”
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