Search Results - "Hyon-seung Yi"
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Overview of growth differentiation factor 15 in metabolic syndrome
Published in Journal of cellular and molecular medicine (01-05-2023)“…Growth and differentiation factor 15 (GDF15) is a member of the transforming growth factor‐β (TGF‐β) superfamily. GDF15 has been linked with several metabolic…”
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The mitochondrial unfolded protein response and mitohormesis: a perspective on metabolic diseases
Published in Journal of molecular endocrinology (01-10-2018)“…Mitochondria perform essential roles as crucial organelles for cellular and systemic energy homeostasis, and as signaling hubs, which coordinate nuclear…”
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3
Dysregulation of mitophagy in carcinogenesis and tumor progression
Published in Biochimica et biophysica acta. Bioenergetics (01-08-2017)“…The mitochondrial role in carcinogenesis and cancer progression is an area of active research, with many unresolved questions. Various aspects of altered…”
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Exosome‐mediated activation of toll‐like receptor 3 in stellate cells stimulates interleukin‐17 production by γδ T cells in liver fibrosis
Published in Hepatology (Baltimore, Md.) (01-08-2016)“…During liver injury, hepatocytes secrete exosomes that include diverse types of self‐RNAs. Recently, self‐noncoding RNA has been recognized as an activator of…”
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Type 2 deiodinase Thr92Ala polymorphism is associated with a reduction in bone mineral density: A community‐based korean genome and epidemiology study
Published in Clinical endocrinology (Oxford) (01-09-2020)“…Objective Type 2 deiodinase (DIO2)‐mediated thyroid hormone synthesis stimulates osteoblast activity and increases the expression of osteoblast differentiation…”
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Growth differentiation factor 15 protects against the aging‐mediated systemic inflammatory response in humans and mice
Published in Aging cell (01-08-2020)“…Mitochondrial dysfunction is associated with aging‐mediated inflammatory responses, leading to metabolic deterioration, development of insulin resistance, and…”
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Implications of Mitochondrial Unfolded Protein Response and Mitokines: A Perspective on Fatty Liver Diseases
Published in Endocrinology and metabolism (Seoul) (01-03-2019)“…The signaling network of the mitochondrial unfolded protein response (UPR ) and mitohormesis is a retrograde signaling pathway through which…”
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8
Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis
Published in The Journal of cell biology (02-01-2017)“…Reduced mitochondrial electron transport chain activity promotes longevity and improves energy homeostasis via cell-autonomous and -non-autonomous factors in…”
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Pro-inflammatory hepatic macrophages generate ROS through NADPH oxidase 2 via endocytosis of monomeric TLR4–MD2 complex
Published in Nature communications (21-12-2017)“…Reactive oxygen species (ROS) contribute to the development of non-alcoholic fatty liver disease. ROS generation by infiltrating macrophages involves multiple…”
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10
Tetracycline Antibiotics Induce Host-Dependent Disease Tolerance to Infection
Published in Immunity (Cambridge, Mass.) (12-01-2021)“…Several classes of antibiotics have long been known to have beneficial effects that cannot be explained strictly on the basis of their capacity to control the…”
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11
Exosomes derived from palmitic acid-treated hepatocytes induce fibrotic activation of hepatic stellate cells
Published in Scientific reports (16-06-2017)“…Non-alcoholic fatty liver disease (NAFLD) is a dominant cause of chronic liver disease, but the exact mechanism of progression from simple steatosis to…”
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12
Sclerostin as a Putative Myokine in Sarcopenia
Published in Endocrinology and metabolism (Seoul) (01-06-2022)“…KCI Citation Count: 0…”
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13
The Role of Carnitine Orotate Complex in Fatty Liver
Published in Diabetes & metabolism journal (30-11-2021)Get full text
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14
Sclerostin as a Putative Myokine in Sarcopenia
Published in Endocrinology and metabolism (Seoul) (30-06-2022)Get full text
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15
GDF15 deficiency exacerbates chronic alcohol- and carbon tetrachloride-induced liver injury
Published in Scientific reports (08-12-2017)“…Growth differentiation factor 15 (GDF15) has recently been shown to have an important role in the regulation of mitochondrial function and in the pathogenesis…”
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16
Reduced oxidative capacity in macrophages results in systemic insulin resistance
Published in Nature communications (19-04-2018)“…Oxidative functions of adipose tissue macrophages control the polarization of M1-like and M2-like phenotypes, but whether reduced macrophage oxidative function…”
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The Role of Carnitine Orotate Complex in Fatty Liver
Published in Diabetes & metabolism journal (01-11-2021)“…Editorial KCI Citation Count: 0…”
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18
Hepatic Immune Microenvironment in Alcoholic and Nonalcoholic Liver Disease
Published in BioMed research international (01-01-2017)“…Many types of innate (natural killer cells, natural killer T cells, and Kupffer cells/macrophages) and adaptive (T cells and B cells) immune cells are enriched…”
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An adipocyte-specific defect in oxidative phosphorylation increases systemic energy expenditure and protects against diet-induced obesity in mouse models
Published in Diabetologia (01-04-2020)“…Aims/hypothesis Mitochondrial oxidative phosphorylation (OxPhos) is essential for energy production and survival. However, the tissue-specific and systemic…”
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20
Immunometabolic signatures predict recovery from thyrotoxic myopathy in patients with Graves' disease
Published in Journal of cachexia, sarcopenia and muscle (01-02-2022)“…Background Thyroid hormone excess induces protein energy wasting, which in turn promotes muscle weakness and bone loss in patients with Graves' disease…”
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