Search Results - "Hylind, James C"

Type 1 and type 2 tumor infiltrating effector cell subpopulations in progressive breast cancer by Reome, Joyce B, Hylind, James C, Dutton, Richard W, Dobrzanski, Mark J

“…Effector T cells fall into two subpopulations based on cytokine-secretion. Type 1 cells secrete IFN-γ, whereas type 2 cells secrete IL-4, IL-10, and GM-CSF…”
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CD8-Mediated Type 1 Antitumor Responses Selectively Modulate Endogenous Differentiated and Nondifferentiated T Cell Localization, Activation, and Function in Progressive Breast Cancer by Dobrzanski, Mark J, Reome, Joyce B, Hylind, James C, Rewers-Felkins, Kathleen A

“…CD8 T cell-mediated immune responses fall into two distinct types based on effector cell-derived cytokine production. Type I CD8 T cells (Tc1) produce…”
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Ag-specific type 1 CD8 effector cells enhance methotrexate-mediated antitumor responses by modulating differentiated T cell localization, activation and chemokine production in established breast cancer by Dobrzanski, Mark J, Reome, Joyce B, Hylind, James C, Rewers-Felkins, Kathleen A, Abulsamad, Khaliquzzaman, Adams, Shawna L

“…Abstract The chemotherapeutic agent methotrexate is widely used in the treatment of breast cancer. Although its mechanism-of-action has been defined, less is…”
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Effector cell-derived lymphotoxin alpha and Fas ligand, but not perforin, promote Tc1 and Tc2 effector cell-mediated tumor therapy in established pulmonary metastases by Dobrzanski, Mark J, Reome, Joyce B, Hollenbaugh, Joseph A, Hylind, James C, Dutton, Richard W

“…Cytolytic CD8(+) effector cells fall into two subpopulations based on cytokine secretion. Type 1 CD8(+) T cells (Tc1) secrete IFN-gamma, whereas type 2 CD8(+)…”
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Ag-Specific Type 1 CD8 Effector Cells Enhance Methotrexate-Mediated Antitumor Responses by Modulating Endogenous CD49b-Expressing CD4 and CD8 T Effector Cell Subpopulations Producing IL-10 by Dobrzanski, Mark J., Reome, Joyce B., Hylind, James C., Rewers-Felkins, Kathleen A., Abdulsamad, Khaliquzzaman, Adams, Shawna L.

“…The chemotherapeutic agent methotrexate is widely used in the treatment of breast cancer. Although its mechanism-of-action has been defined, less is known…”
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Effector cell-derived lymphotoxin a and Fas ligand, but not perforin, promote Tcl and Tc2 effector cell-mediated tumor therapy in established pulmonary metastases by DOBRZANSKI, Mark J, REOME, Joyce B, HOLLENBAUGH, Joseph A, HYLIND, James C, DUTTON, Richard W

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