Search Results - "Hyjek‐Składanowska, Malwina"

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  1. 1

    Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins by Hyjek-Składanowska, Malwina, Vickers, Timothy A, Napiórkowska, Agnieszka, Anderson, Brooke A, Tanowitz, Michael, Crooke, Stanley T, Liang, Xue-hai, Seth, Punit P, Nowotny, Marcin

    Published in Journal of the American Chemical Society (22-04-2020)
    “…The phosphorothioate backbone modification (PS) is one of the most widely used chemical modifications for enhancing the drug-like properties of nucleic…”
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    Journal Article
  2. 2

    Core spliceosomal Sm proteins as constituents of cytoplasmic mRNPs in plants by HyjekSkładanowska, Malwina, Bajczyk, Mateusz, Gołębiewski, Marcin, Nuc, Przemysław, Kołowerzo‐Lubnau, Agnieszka, Jarmołowski, Artur, Smoliński, Dariusz Jan

    “…SUMMARY In recent years, research has increasingly focused on the key role of post‐transcriptional regulation of messenger ribonucleoprotein (mRNP) function…”
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    Journal Article
  3. 3

    Different Patterns of mRNA Nuclear Retention during Meiotic Prophase in Larch Microsporocytes by Majewska, Karolina, Wróblewska-Ankiewicz, Patrycja, Rudzka, Magda, Hyjek-Składanowska, Malwina, Gołębiewski, Marcin, Smoliński, Dariusz Jan, Kołowerzo-Lubnau, Agnieszka

    “…Recent studies show a crucial role of post-transcriptional processes in the regulation of gene expression. Our research has shown that mRNA retention in the…”
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    Journal Article
  4. 4

    Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding by Hyjek-Składanowska, Malwina, Anderson, Brooke A, Mykhaylyk, Vitaliy, Orr, Christian, Wagner, Armin, Poznański, Jarosław T, Skowronek, Krzysztof, Seth, Punit, Nowotny, Marcin

    Published in Nucleic acids research (22-02-2023)
    “…The introduction of phosphorothioate (PS) linkages to the backbone of therapeutic nucleic acids substantially increases their stability and potency. It also…”
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  5. 5

    Functional nuclear retention of pre-mRNA involving Cajal bodies during meiotic prophase in European larch (Larix decidua) by Rudzka, Magda, Wróblewska-Ankiewicz, Patrycja, Majewska, Karolina, Hyjek-Składanowska, Malwina, Gołębiewski, Marcin, Sikora, Marcin, Smoliński, Dariusz Jan, Kołowerzo-Lubnau, Agnieszka

    Published in The Plant cell (24-05-2022)
    “…Gene regulation ensures that the appropriate genes are expressed at the proper time. Nuclear retention of incompletely spliced or mature mRNAs is emerging as a…”
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  6. 6

    Disulfide bridge cross-linking between protein and the RNA backbone as a tool to study RNase H1 by Hyjek-Składanowska, Malwina, Stasińska, Anna R., Napiórkowska-Gromadzka, Agnieszka, Bartłomiejczak, Aneta, Seth, Punit P., Chmielewski, Marcin K., Nowotny, Marcin

    Published in Bioorganic & medicinal chemistry (01-12-2020)
    “…[Display omitted] The chemical cross-linking of complexes of proteins with nucleic acids is often used in structural and mechanistic studies of these…”
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  7. 7

    Reproducible and efficient new method of RNA 3'-end labelling by CutA nucleotidyltransferase-mediated CC-tailing by Tomecki, Rafal, Kobylecki, Kamil, Drazkowska, Karolina, Hyjek-Skladanowska, Malwina, Dziembowski, Andrzej

    Published in RNA biology (12-11-2021)
    “…Despite the development of non-radioactive DNA/RNA labelling methods, radiolabelled nucleic acids are commonly used in studies focused on the determination of…”
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    Journal Article
  8. 8

    Reproducible and efficient new method of RNA 3'-end labelling by CutA nucleotidyltransferase-mediated CC-tailing by Tomecki, Rafal, Kobylecki, Kamil, Drazkowska, Karolina, Hyjek-Skladanowska, Malwina, Dziembowski, Andrzej

    Published in RNA Biology (12-11-2021)
    “…Despite the development of non-radioactive DNA/RNA labelling methods, radiolabelled nucleic acids are commonly used in studies focused on the determination of…”
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