Search Results - "Hyer, Jeanette"
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Characterization of a diffuse intrinsic pontine glioma cell line: implications for future investigations and treatment
Published in Journal of neuro-oncology (01-12-2012)“…Diffuse intrinsic pontine gliomas arise almost exclusively in children, and despite advances in treatment, the majority of patients die within 2 years after…”
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2
Central and peripheral retina arise through distinct developmental paths
Published in PloS one (16-04-2013)“…In the mature eye, three distinct tissue fates, retina, ciliary body, and iris, arrange with a strict linear organization along the central (back) to…”
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3
FGF1 patterns the optic vesicle by directing the placement of the neural retina domain
Published in Development (Cambridge) (01-03-1998)“…Patterning of the bipotential retinal primordia (the optic vesicles) into neural retina and retinal pigmented epithelium depends on its interaction with…”
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4
A genetic strategy to overcome the senescence of primary meningioma cell cultures
Published in Journal of neuro-oncology (01-06-2006)“…Even though meningiomas are the second most common brain tumor in adults, little is known about the molecular basis of their growth and development. The lack…”
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5
Induction of Purkinje fiber differentiation by coronary arterialization
Published in Proceedings of the National Academy of Sciences - PNAS (09-11-1999)“…A synchronized heart beat is controlled by pacemaking impulses conducted through Purkinje fibers. In chicks, these impulse-conducting cells are recruited…”
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CNSC-66. STRUCTURAL AND ELECTROPHYSIOLOGICAL CONNECTIVITY IN GLIOBLASTOMA IS MEDIATED BY TUMOR AND IMMUNE DERIVED CYTOKINES
Published in Neuro-oncology (Charlottesville, Va.) (11-11-2024)“…Abstract BACKGROUND In glioblastomas (GBM), the pleiotropic cytokine interleukin-6 (IL-6) upregulates PD-L1 expression. This results in local immunosuppression…”
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7
Glioblastoma remodelling of human neural circuits decreases survival
Published in Nature (London) (18-05-2023)“…Gliomas synaptically integrate into neural circuits 1 , 2 . Previous research has demonstrated bidirectional interactions between neurons and glioma cells,…”
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Early divergence of central and peripheral neural retina precursors during vertebrate eye development
Published in Developmental dynamics (01-03-2015)“…ABSTRACT Background: During development of the vertebrate eye, optic tissue is progressively compartmentalized into functionally distinct tissues. From the…”
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Optic cup morphogenesis requires pre-lens ectoderm but not lens differentiation
Published in Developmental biology (15-07-2003)“…The formation of the vertebrate optic cup is a morphogenetic event initiated after the optic vesicle contacts the overlying surface/pre-lens ectoderm. Placodes…”
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10
The expression of Wnt2b in the optic cup lip requires a border between the pigmented and nonpigmented epithelium
Published in Molecular vision (14-12-2010)“…Wnt2b is normally expressed at the optic cup lip and is implicated in ciliary body induction. The lens has often been considered an organizer for the anterior…”
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Looking at an oft-overlooked part of the eye: a new perspective on ciliary body development in chick
Published in Developmental neuroscience (01-01-2004)“…The ciliary body is an essential tissue for the development and homeostasis of the vertebrate eye. Embryonically, the epithelial portion of the ciliary body…”
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Signals involved in establishment of ciliary body cell fate in developing vertebrate optic cup
Published in Developmental biology (01-06-2007)Get full text
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WITHDRAWN: Signals involved in establishment of ciliary body cell fate in developing vertebrate optic cup
Published in Developmental biology (01-04-2007)Get full text
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14
FGF-mediated induction of ciliary body tissue in the chick eye
Published in Developmental biology (01-04-2007)“…Upon morphogenesis, the simple neuroepithelium of the optic vesicle gives rise to four basic tissues in the vertebrate optic cup: pigmented epithelium, sensory…”
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15
Retinal and anterior eye compartments derive from a common progenitor pool in the avian optic cup
Published in Molecular vision (20-12-2011)“…The optic cup is created through invagination of the optic vesicle. The morphogenetic rearrangement creates a double-layered cup, with a hinge (the Optic Cup…”
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Distinct patterns of human medulloblastoma dissemination in the developing chick embryo nervous system
Published in Clinical & experimental metastasis (01-04-2012)“…Medulloblastoma (MB) is the most common malignant primary brain tumor in children. Aggressive tumors that disseminate along the leptomeninges carry extremely…”
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Murine retroviruses re‐engineered for lineage tracing and expression of toxic genes in the developing chick embryo
Published in Developmental dynamics (01-11-2008)“…We describe two replication incompetent retroviral vectors that co‐express green fluorescent protein (GFP) and beta‐galactosidase. These vectors incorporate…”
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18
Hairy function as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation
Published in Genes & development (15-11-1994)“…Sensory organ formation in Drosophila is activated by proneural genes that encode basic-helix-loop-helix (bHLH) transcription factors. These genes are…”
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Retroviral techniques for studying organogenesis with a focus on heart development
Published in Molecular and cellular biochemistry (01-07-1997)“…The study of development has been revolutionized by the application of molecular techniques, which make it possible to identify factors involved in the…”
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Early inductions in eye development
Published 1998“…The optic vesicle is the embryonic precursor of the optic cup. The optic vesicle starts in the neural tube as a bulge that grows laterally and subsequently…”
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Dissertation