Search Results - "Hyeong-chan Lee"
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Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A
Published in Nature communications (27-03-2019)“…Inhibitors of the secretion of cancer exosomes, which promote cancer progression and metastasis, may not only accelerate exosome biology research but also…”
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2
Development of Novel Epigenetic Anti-Cancer Therapy Targeting TET Proteins
Published in International journal of molecular sciences (01-11-2023)“…Epigenetic dysregulation, particularly alterations in DNA methylation and hydroxymethylation, plays a pivotal role in cancer initiation and progression…”
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3
Discovery of a diagnostic biomarker for colon cancer through proteomic profiling of small extracellular vesicles
Published in BMC cancer (01-11-2018)“…Small extracellular vesicles (small-EVs) are membranous vesicles that contain unique information regarding the condition of cells and contribute to the…”
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Novel urinary exosomal biomarkers of acute T cell-mediated rejection in kidney transplant recipients: A cross-sectional study
Published in PloS one (18-09-2018)“…Acute rejection is hazardous to graft survival in kidney transplant recipients (KTRs). We aimed to identify novel biomarkers for early diagnosis of acute T…”
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5
Sulfisoxazole Elicits Robust Antitumour Immune Response Along with Immune Checkpoint Therapy by Inhibiting Exosomal PD‐L1
Published in Advanced science (01-02-2022)“…Despite their potent antitumor activity, clinical application of immune checkpoint inhibitors has been significantly limited by their poor response rates…”
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6
Plum Prevents Intestinal and Hepatic Inflammation in the Acute and Chronic Models of Dextran Sulfate Sodium‐Induced Mouse Colitis
Published in Molecular nutrition & food research (01-07-2022)“…Scope Inflammatory bowel disease (IBD), including ulcerative colitis (UC), is a chronic recurrent inflammatory disease of the digestive tract and increases the…”
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Reprogramming of T cell‐derived small extracellular vesicles using IL2 surface engineering induces potent anti‐cancer effects through miRNA delivery
Published in Journal of extracellular vesicles (01-12-2022)“…T cell‐derived small extracellular vesicles (sEVs) exhibit anti‐cancer effects. However, their anti‐cancer potential should be reinforced to enhance clinical…”
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8
Cathepsin D promotes polarization of tumor-associated macrophages and metastasis through TGFBI-CCL20 signaling
Published in Experimental & molecular medicine (01-02-2024)“…M2-like tumor-associated macrophages (TAMs) are risk factors for cancer progression and metastasis. However, the mechanisms underlying their polarization are…”
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Reply to ‘Sulfisoxazole does not inhibit the secretion of small extracellular vesicles’
Published in Nature communications (12-02-2021)Get full text
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10
Identification of a novel non-invasive biological marker to overcome the shortcomings of PSA in diagnosis and risk stratification for prostate cancer: Initial prospective study of developmental endothelial locus-1 protein
Published in PloS one (26-04-2021)“…This prospective study sought to clarify the developmental endothelial locus-1 (Del-1) protein as values of diagnosis and risk stratification of prostate…”
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11
Role of Core-Based Exercises in Improving Proprioception among Individuals with Neurological Disorders: A Systematic Literature Review and Meta-Analysis
Published in Exercise science (Seoul, Korea) (31-05-2024)“…PURPOSE This study aimed to validate the effect of core-based exercise on proprioception in individuals with neurological disorders through a systematic review…”
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Extracellular vesicle isolation and counting system (EVics) based on simultaneous tandem tangential flow filtration and large field‐of‐view light scattering
Published in Journal of extracellular vesicles (01-07-2024)“…Although the isolation and counting of small extracellular vesicles (sEVs) are essential steps in sEV research, an integrated method with scalability and…”
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13
Dissecting exosome inhibitors: therapeutic insights into small-molecule chemicals against cancer
Published in Experimental & molecular medicine (01-11-2022)“…Intensive research in the field of cancer biology has revealed unique methods of communication between cells through extracellular vesicles called exosomes…”
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14
생활체육인들의 참여 빈도와 부상 정도의 관계에서 기술 수준의 매개효과: 부상률이 가장 높은 구기종목을 중심으로
Published in Ch'eyuk kwahak yŏn'gu (31-03-2024)“…[목적] 본 연구 부상률이 높은 생활체육 종목 중 구기 종목에 참여하는 생활체육인을 대상으로 참여 빈도와 부상 정도의 관계에서 기술 수준의 매개효과를 확인하는데 목적이 있다. [방법] 본 연구는 ‘2019 스포츠 안전사고 데이터’의 원자료를 사용하여 부상률이 가장 높게 나타난 4가지…”
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15
Mediation Effect of Skill Levels in Relationship Between Degree of Participation and Injury Experience on Leisure Sports Participants : Based on Ball Sports with the Highest Injury Rate
Published in Ch'eyuk kwahak yŏn'gu (01-03-2024)“…PURPOSE This study aimed to prove the mediator effect of skill level on participation frequency and injury level of leisure sports players with the highest…”
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Yam-derived exosome-like nanovesicles stimulate osteoblast formation and prevent osteoporosis in mice
Published in Journal of controlled release (01-03-2023)“…Plants-releasing exosome-like nanovesicles (PENs) contain miRNA, bioactive lipids, mRNAs, and proteins to exert antioxidant, anti-inflammatory, and…”
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Macitentan improves antitumor immune responses by inhibiting the secretion of tumor-derived extracellular vesicle PD-L1
Published in Theranostics (01-01-2022)“…Extracellular vesicles (EVs) carrying tumor cell-derived programmed death-ligand 1 (PD-L1) interact with programmed death 1 (PD-1)-producing T cells, thus…”
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Atorvastatin Enhances the Efficacy of Immune Checkpoint Therapy and Suppresses the Cellular and Extracellular Vesicle PD-L1
Published in Pharmaceutics (01-08-2022)“…According to clinical studies, statins improve the efficacy of programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) blockade therapy for breast cancer;…”
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Potential urinary extracellular vesicle protein biomarkers of chronic active antibody-mediated rejection in kidney transplant recipients
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (01-02-2020)“…•A proteomic approach was employed to measure urinary extracellular vesicle changes in KTRs.•CAMR and two controls (LGS and rejection-free matched control)…”
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20
Repackaging Attack on Android Banking Applications and Its Countermeasures
Published in Wireless personal communications (01-12-2013)“…Although anyone can easily publish Android applications (or apps) in an app marketplace according to an open policy, decompiling the apps is also easy due to…”
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