Search Results - "Hye Sook Kim"

Anticancer Strategy Targeting Cell Death Regulators: Switching the Mechanism of Anticancer Floxuridine-Induced Cell Death from Necrosis to Apoptosis by Sato, Akira, Hiramoto, Akiko, Kim, Hye-Sook, Wataya, Yusuke

“…Cell death can be broadly characterized as either necrosis or apoptosis, depending on the morphological and biochemical features of the cell itself. We have…”
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The Brucella abortus virulence regulator, LovhK, is a sensor kinase in the general stress response signalling pathway by Kim, Hye‐Sook, Willett, Jonathan W., Jain‐Gupta, Neeta, Fiebig, Aretha, Crosson, Sean

“…Summary In the intracellular pathogen Brucella abortus, the general stress response (GSR) signalling system determines survival under acute stress conditions…”
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Host range and molecular phylogenies of the soft rot enterobacterial genera Pectobacterium and Dickeya by BING MA, HIBBING, Michael E, CHARKOWSKI, Amy O, KIM, Hye-Sook, REEDY, Ralph M, YEDIDIA, Iris, BREUER, Jane, BREUER, Jeffrey, GLASNER, Jeremy D, PERNA, Nicole T, KELMAN, Arthur

“…ABSTRACT Pectobacterium and Dickeya spp. are related broad-host-range entero-bacterial pathogens of angiosperms. A review of the literature shows that these…”
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Extract of Torreya nucifera Pericarps Exhibits a Parasiticidal Effect on the Nematode Parasite, Trichinella spiralis by Jeong, Mi Jin, Kang, Shin Ae, Yu, Sun Nyoung, Ahn, Soon Cheol, Miyoshi, Shin-Ichi, Kim, Hye-Sook, Yu, Hak Sun

“…Benzimidazole derivatives can effectively treat nematode parasitic infections; however, some derivatives demand distinct administrative strategies depending on…”
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Phylogeny and Virulence of Naturally Occurring Type III Secretion System-Deficient Pectobacterium Strains by Kim, Hye-Sook, Ma, Bing, Perna, Nicole T, Charkowski, Amy O

“…Pectobacterium species are enterobacterial plant-pathogenic bacteria that cause soft rot disease in diverse plant species. Previous epidemiological studies of…”
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Role of activating transcription factor 3 protein ATF3 in necrosis and apoptosis induced by 5‐fluoro‐2′‐deoxyuridine by Sato, Akira, Nakama, Kentaro, Watanabe, Hiroki, Satake, Akito, Yamamoto, Akihiro, Omi, Takuya, Hiramoto, Akiko, Masutani, Mitsuko, Wataya, Yusuke, Kim, Hye‐Sook

“…Necrosis and apoptosis are the two major forms of cell death. We have studied the mechanisms that regulate the cell death observed during treatment of mouse…”
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Anti-Diabetic Potential of Sargassum horneri and Ulva australis Extracts In Vitro and In Vivo by Lee, Young-Hyeon, Kim, Hye-Ran, Yeo, Min-Ho, Kim, Sung-Chun, Hyun, Ho-Bong, Ham, Young-Min, Jung, Yong-Hwan, Kim, Hye-Sook, Chang, Kyung-Soo

“…Sargassum horneri (SH) and Ulva australis (UA) are marine waste resources that cause environmental and economic problems when entering or multiplying the…”
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MicroRNA-351 Regulates Two-Types of Cell Death, Necrosis and Apoptosis, Induced by 5-fluoro-2'-deoxyuridine by Sato, Akira, Omi, Takuya, Yamamoto, Akihiro, Satake, Akito, Hiramoto, Akiko, Masutani, Mitsuko, Tanuma, Sei-ichi, Wataya, Yusuke, Kim, Hye-Sook

“…Cell-death can be necrosis and apoptosis. We are investigating the mechanisms regulating the cell death that occurs on treatment of mouse cancer cell-line FM3A…”
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Direct interaction analysis of microRNA-351-5p and nuclear scaffold lamin B1 mRNA by the cell-free in vitro mRNA/miRNA binding evaluation system by Sato, Akira, Ogino, Yoko, Shimotsuma, Akira, Hiramoto, Akiko, Kim, Hye-Sook, Wataya, Yusuke

“…We previously demonstrated that miR-351-5p regulates nuclear scaffold lamin B1 expression and mediates the anticancer floxuridine-induced necrosis shift to…”
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Role of the uridine/cytidine kinase 2 mutation in cellular sensitiveness toward 3'-ethynylcytidine treatment of human cancer cells by Sato, Akira, Takano, Takeshi, Hiramoto, Akiko, Naito, Tomoharu, Matsuda, Akira, Fukushima, Masakazu, Wataya, Yusuke, Kim, Hye-Sook

“…A nucleosidic medicine, 1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine [3'-ethynylcytidine (ECyd)], is a potent inhibitor of RNA polymerase I and shows…”
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Intracellular microRNA expression patterns influence cell death fates for both necrosis and apoptosis by Sato, Akira, Yamamoto, Akihiro, Shimotsuma, Akira, Ogino, Yoko, Funayama, Naoki, Takahashi, Yui, Hiramoto, Akiko, Wataya, Yusuke, Kim, Hye‐Sook

“…We reveal that intracellular miRNA expression patterns are dramatically altered in necrosis and apoptosis using a floxuridine (FUdR)‐induced mouse mammary…”
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Andirolides H–P from the flower of andiroba (Carapa guianensis, Meliaceae) by Tanaka, Yuji, Sakamoto, Asami, Inoue, Takanobu, Yamada, Takeshi, Kikuchi, Takashi, Kajimoto, Tetsuya, Muraoka, Osamu, Sato, Akira, Wataya, Yusuke, Kim, Hye-Sook, Tanaka, Reiko

“…Three new gedunins, an andirobin, three mexicanolides, and two phragmalin-type limonoids named andirolides H (1), I (2), J (3), K (4), L (5), M (6), N (7), O…”
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Identification and Characterization of a Novel Species of Genus Akkermansia with Metabolic Health Effects in a Diet-Induced Obesity Mouse Model by Kumar, Ritesh, Kane, Helene, Wang, Qiong, Hibberd, Ashley, Jensen, Henrik Max, Kim, Hye-Sook, Bak, Steffen Yde, Auzanneau, Isabelle, Bry, Stéphanie, Christensen, Niels, Friedman, Andrew, Rasinkangas, Pia, Ouwehand, Arthur C., Forssten, Sofia D., Hasselwander, Oliver

“…Akkermansia muciniphila is a well-known bacterium with the ability to degrade mucin. This metabolic capability is believed to play an important role in the…”
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Oral activity of the antimalarial endoperoxide 6-(1,2,6,7-tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol (N-251) against Leishmania donovani complex by Kwofie, Kofi Dadzie, Sato, Kai, Sanjoba, Chizu, Hino, Akina, Shimogawara, Rieko, Amoa-Bosompem, Michael, Ayi, Irene, Boakye, Daniel A, Anang, Abraham K, Chang, Kyung-Soo, Ohashi, Mitsuko, Kim, Hye-Sook, Ohta, Nobuo, Matsumoto, Yoshitsugu, Iwanaga, Shiroh

“…Visceral leishmaniasis (VL) is a major problem worldwide and causes significant morbidity and mortality. Existing drugs against VL have limitations, including…”
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Pectobacterium carotovorum Elicits Plant Cell Death with DspE/F but the P. carotovorum DspE Does Not Suppress Callose or Induce Expression of Plant Genes Early in Plant–Microbe Interactions by Kim, Hye-Sook, Thammarat, Phanit, Lommel, Steven A, Hogan, Clifford S, Charkowski, Amy O

“…The broad-host-range bacterial soft rot pathogen Pectobacterium carotovorum causes a DspE/F-dependent plant cell death on Nicotiana benthamiana within 24 h…”
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Anti-Obesity Potential of Sargassum horneri and Ulva australis Extracts: Study In Vitro and In Vivo by Lee, Young-Hyeon, Kim, Hye-Ran, Yeo, Min-Ho, Kim, Sung Chun, Hyun, Ho-Bong, Ham, Young-Min, Jung, Yong-Hwan, Kim, Hye-Sook, Chang, Kyung-Soo

“…Current research highlights the use of natural products or phytochemicals as drugs and functional additives to treat obesity with few side effects. Sargassum…”
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Maternal and Fetal Effects of Gestational Vitamin D Concentration by Kwon, Ki-Wook, Lee, Young-Hyeon, Yeo, Min-Ho, Park, Sang-Hyun, Kim, Hye-Ran, Kim, Hye-Sook, Chang, Kyung-Soo

“…Most (90%) vitamin D synthesis occurs in the skin using sunlight (ultraviolet rays), and 10% is obtained through food. Vitamin D is an essential nutrient for…”
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Identification and characterization of Chryseobacterium wanjuense strain KJ9C8 as a biocontrol agent of Phytophthora blight of pepper by Kim, Hye-Sook, Sang, Mee Kyung, Jung, Ho Won, Jeun, Yong-Chull, Myung, Inn-Shik, Kim, Ki Deok

“…Several Chryseobacterium species associated with the suppression of soilborne plant pathogens have been identified, but little is known about the properties of…”
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Pioneer Use of Antimalarial Transdermal Combination Therapy in Rodent Malaria Model by Aly, Nagwa S M, Matsumori, Hiroaki, Dinh, Thi Quyen, Sato, Akira, Miyoshi, Shin-Ichi, Chang, Kyung-Soo, Yu, Hak Sun, Cao, Duc Tuan, Kim, Hye-Sook

“…We have previously reported 1,2,6,7-tetraoxaspiro [7.11]nonadecane (N-89) as a promising antimalarial compound. In this study, we evaluated the effect of…”
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Pharmacokinetic analysis of new synthetic antimalarial N-251 by Okada, Kazuaki, Sato, Akira, Hiramoto, Akiko, Isogawa, Rena, Kurosaki, Yuji, Higaki, Kazutaka, Miyoshi, Shin-Ichi, Chang, Kyung-Soo, Kim, Hye-Sook

“…With the emergence and growing number of drug-resistant , a new drug for malaria control must be urgently developed. The new antimalarial synthetic compound…”
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