Search Results - "Hye Gwang Jeong"
-
1
Metallothionein 3 Promotes Osteoblast Differentiation in C2C12 Cells via Reduction of Oxidative Stress
Published in International journal of molecular sciences (21-04-2021)“…Metallothioneins (MTs) are intracellular cysteine-rich proteins, and their expressions are enhanced under stress conditions. MTs are recognized as having the…”
Get full text
Journal Article -
2
The flavonoids apigenin and luteolin suppress ultraviolet A-induced matrix metalloproteinase-1 expression via MAPKs and AP-1-dependent signaling in HaCaT cells
Published in Journal of dermatological science (01-01-2011)“…Abstract Background Ultraviolet (UV) irradiation causes major changes in skin connective tissues as a result of the degradation of collagen, a major structural…”
Get full text
Journal Article -
3
Integration of transcriptomics, proteomics and metabolomics identifies biomarkers for pulmonary injury by polyhexamethylene guanidine phosphate (PHMG-p), a humidifier disinfectant, in rats
Published in Archives of toxicology (01-03-2020)“…Polyhexamethylene guanidine phosphate (PHMG-p) was used as a humidifier disinfectant in Korea. PHMG induced severe pulmonary fibrosis in Koreans. The objective…”
Get full text
Journal Article -
4
Novel benzofuran derivative DK-1014 attenuates lung inflammation via blocking of MAPK/AP-1 and AKT/mTOR signaling in vitro and in vivo
Published in Scientific reports (29-01-2019)“…Benzofuran derivatives have wide range of biological activities as anti-oxidant, anti-inflammatory and anticonvulsant agent. In this study, we investigated…”
Get full text
Journal Article -
5
DK-1108 exerts anti-inflammatory activity against phorbol 12-myristate 13-acetate-induced inflammation and protective effect against OVA-induced allergic asthma
Published in Biomedicine & pharmacotherapy (01-12-2020)“…[Display omitted] •We tested the in vivo/in vitro anti-asthmatic effects of novel benzofuran, DK-1108.•DK-1108 blocked inflammatory cytokines/chemokines and…”
Get full text
Journal Article -
6
Houttuynia cordata water extract suppresses anaphylactic reaction and IgE-mediated allergic response by inhibiting multiple steps of FcεRI signaling in mast cells
Published in Food and chemical toxicology (01-07-2009)“…Houttuynia cordata has been used as a traditional medicine in Korea and is known to have antioxidant, anti-cancer and anti-allergic activities. The precise…”
Get full text
Journal Article -
7
Upregulation of Stat1-HDAC4 confers resistance to etoposide through enhanced multidrug resistance 1 expression in human A549 lung cancer cells
Published in Molecular medicine reports (01-03-2015)“…Despite efforts to develop efficient chemotherapeutic drug strategies to treat cancer, acquired drug resistance is a commonly encountered problem. In the…”
Get full text
Journal Article -
8
Current Trends of Exercise Programs for Improving Cognitive Function in Older Adults
Published in Exercise science (Seoul, Korea) (01-08-2024)“…PURPOSE Limited studies have analyzed exercise protocols for cognitive improvement in older adults. Therefore, we closely examined the composition, content,…”
Get full text
Journal Article -
9
Aromadendrin Inhibits Lipopolysaccharide-Induced Inflammation in BEAS-2B Cells and Lungs of Mice
Published in Biomolecules & therapeutics (01-09-2024)“…Aromadendrin is a phenolic compound with various biological effects such as anti-inflammatory properties. However, its protective effects against acute lung…”
Get full text
Journal Article -
10
Metformin induces microRNA-34a to downregulate the Sirt1/Pgc-1α/Nrf2 pathway, leading to increased susceptibility of wild-type p53 cancer cells to oxidative stress and therapeutic agents
Published in Free radical biology & medicine (01-09-2014)“…Sirtuin 1 (Sirt1) plays an important role in cellular redox balance and resistance to oxidative stress. Sirt1 exhibits oncogenic properties in wild-type p53…”
Get full text
Journal Article -
11
N -Acetylglucosamine suppress collagenases activation in ultraviolet B-irradiated human dermal fibroblasts: Involvement of calcium ions and mitogen-activated protein kinases
Published in Journal of dermatological science (01-08-2011)“…Summary Background N -Acetylglucosamine (GlcNAc) and its derivates have been utilized in dietary supplements and for therapeutic development due to their…”
Get full text
Journal Article -
12
노인 인지기능 향상을 위한 운동프로그램 최신 동향
Published in Exercise science (Seoul, Korea) (31-08-2024)“…PURPOSE: Limited studies have analyzed exercise protocols for cognitive improvement in older adults. Therefore, we closely examined the composition, content,…”
Get full text
Journal Article -
13
Anti-Inflammatory Activities of Methanol Extract of Mastixia arborea C.B. Clarke as to Mouse Macrophage and Paw Edema
Published in Bioscience, biotechnology, and biochemistry (2013)“…The biological activity of Mastixia arborea (MA) relates to inflammation, but the underlying mechanisms are largely unknown. We confirmed the anti-inflammatory…”
Get full text
Journal Article -
14
Inhibitory effect of the saponins derived from roots of Platycodon grandiflorum on carrageenan-induced inflammation
Published in Bioscience, biotechnology, and biochemistry (01-04-2006)“…Previous studies have reported that the saponins isolated from the roots of Platycodon grandiflornm A. DC (Campanulaceae), Changkil saponins (CKS), inhibited…”
Get full text
Journal Article -
15
Puerarin attenuates hepatic steatosis via G‐protein‐coupled estrogen receptor‐mediated calcium and SIRT1 signaling pathways
Published in Phytotherapy research (01-09-2022)“…Puerarin, the major bioactive ingredient isolated from the root of Pueraria lobata (Willd.), attenuates body weight gain and reduces lipid levels in high‐fat…”
Get full text
Journal Article -
16
Ginsenoside Rb1 protects against 6-hydroxydopamine-induced oxidative stress by increasing heme oxygenase-1 expression through an estrogen receptor-related PI3K/Akt/Nrf2-dependent pathway in human dopaminergic cells
Published in Toxicology and applied pharmacology (2010)“…Phytoestrogens are polyphenolic non-steroidal plant compounds with estrogen-like biological activity. Ginseng, the root of Panax ginseng C.A. Meyer…”
Get full text
Journal Article -
17
Protective role of intestinal bacterial metabolism against baicalin-induced toxicity in HepG2 cell cultures
Published in Journal of toxicological sciences (2012)“…Baicalin, a glycoside present in Scutellaria baicalensis Georgi, is metabolized to its aglycone, baicalein, in intestine. In the present study, possible role…”
Get full text
Journal Article -
18
Metformin inhibits heme oxygenase-1 expression in cancer cells through inactivation of Raf-ERK-Nrf2 signaling and AMPK-independent pathways
Published in Toxicology and applied pharmacology (01-09-2013)“…Resistance to therapy is the major obstacle to more effective cancer treatment. Heme oxygenase-1 (HO-1) is often highly up-regulated in tumor tissues, and its…”
Get full text
Journal Article -
19
The coffee diterpene kahweol induces heme oxygenase-1 via the PI3K and p38/Nrf2 pathway to protect human dopaminergic neurons from 6-hydroxydopamine-derived oxidative stress
Published in FEBS letters (23-07-2008)“…In this study, we investigated the mechanisms of kahweol protection of neuronal cells from cell death induced by the Parkinson’s disease-related neurotoxin…”
Get full text
Journal Article -
20
Antitumor efficacy of piperine in the treatment of human HER2-overexpressing breast cancer cells
Published in Food chemistry (01-12-2013)“…•Piperine inhibits proliferation and induces apoptosis by suppressing HER2.•Piperine suppresses SREBP-1 and FAS expression.•Piperine attenuates EGF-induced…”
Get full text
Journal Article