Search Results - "Hyde, Thomas M"

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    Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex by Jaffe, Andrew E, Gao, Yuan, Deep-Soboslay, Amy, Tao, Ran, Hyde, Thomas M, Weinberger, Daniel R, Kleinman, Joel E

    Published in Nature neuroscience (01-01-2016)
    “…DNA methylation in human brain shows dramatic variation across development. Genetic loci implicated in risk for schizophrenia are enriched for epigenetic…”
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    Dynamic regulation of RNA editing in human brain development and disease by Hwang, Taeyoung, Park, Chul-Kee, Leung, Anthony K L, Gao, Yuan, Hyde, Thomas M, Kleinman, Joel E, Rajpurohit, Anandita, Tao, Ran, Shin, Joo Heon, Weinberger, Daniel R

    Published in Nature neuroscience (01-08-2016)
    “…RNA sequences are generally considered to be a mirror of DNA sequences. However, that dogma has become challenged as RNA editing is increasingly recognized…”
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    DNA Methylation Signatures in Development and Aging of the Human Prefrontal Cortex by Numata, Shusuke, Ye, Tianzhang, Hyde, Thomas M., Guitart-Navarro, Xavier, Tao, Ran, Wininger, Michael, Colantuoni, Carlo, Weinberger, Daniel R., Kleinman, Joel E., Lipska, Barbara K.

    Published in American journal of human genetics (10-02-2012)
    “…The human prefrontal cortex (PFC), a mastermind of the brain, is one of the last brain regions to mature. To investigate the role of epigenetics in the…”
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    Temporal dynamics and genetic control of transcription in the human prefrontal cortex by Colantuoni, Carlo, Lipska, Barbara K., Ye, Tianzhang, Hyde, Thomas M., Tao, Ran, Leek, Jeffrey T., Colantuoni, Elizabeth A., Elkahloun, Abdel G., Herman, Mary M., Weinberger, Daniel R., Kleinman, Joel E.

    Published in Nature (London) (27-10-2011)
    “…Gene expression in the human brain Gene expression controls and dictates everything from development and plasticity to ongoing neurogenesis in the brain, yet…”
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    dotdotdot: an automated approach to quantify multiplex single molecule fluorescent in situ hybridization (smFISH) images in complex tissues by Maynard, Kristen R, Tippani, Madhavi, Takahashi, Yoichiro, Phan, BaDoi N, Hyde, Thomas M, Jaffe, Andrew E, Martinowich, Keri

    Published in Nucleic acids research (19-06-2020)
    “…Abstract Multiplex single-molecule fluorescent in situ hybridization (smFISH) is a powerful method for validating RNA sequencing and emerging spatial…”
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    Somatic LINE-1 retrotransposition in cortical neurons and non-brain tissues of Rett patients and healthy individuals by Zhao, Boxun, Wu, Qixi, Ye, Adam Yongxin, Guo, Jing, Zheng, Xianing, Yang, Xiaoxu, Yan, Linlin, Liu, Qing-Rong, Hyde, Thomas M, Wei, Liping, Huang, August Yue

    Published in PLoS genetics (11-04-2019)
    “…Mounting evidence supports that LINE-1 (L1) retrotransposition can occur postzygotically in healthy and diseased human tissues, contributing to genomic…”
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    Investigating trait variability of gene co-expression network architecture in brain by controlling for genomic risk of schizophrenia by Radulescu, Eugenia, Chen, Qiang, Pergola, Giulio, Di Carlo, Pasquale, Han, Shizhong, Shin, Joo Heon, Hyde, Thomas M, Kleinman, Joel E, Weinberger, Daniel R

    Published in PLoS genetics (13-10-2023)
    “…The effect of schizophrenia (SCZ) genetic risk on gene expression in brain remains elusive. A popular approach to this problem has been the application of gene…”
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