Search Results - "Hwang, Wooseon"

A PTEN variant uncouples longevity from impaired fitness in Caenorhabditis elegans with reduced insulin/IGF-1 signaling by Park, Hae-Eun H., Hwang, Wooseon, Ham, Seokjin, Kim, Eunah, Altintas, Ozlem, Park, Sangsoon, Son, Heehwa G., Lee, Yujin, Lee, Dongyeop, Heo, Won Do, Lee, Seung-Jae V.

“…Insulin/IGF-1 signaling (IIS) regulates various physiological aspects in numerous species. In Caenorhabditis elegans , mutations in the daf-2 /insulin/IGF-1…”
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Topical application of Zanthoxylum piperitum extract improves lateral canthal rhytides by inhibiting muscle contractions by Hwang, Wooseon, Kim, Daehyun, Kwon, Oh Sun, Kim, Yun-Sun, Ahn, Byungjun, Kang, Nae-Gyu

“…Facial wrinkles are the predominant phenotypes of skin aging. To date, one of the most effective ways to improve wrinkles is botulinum toxin type A (BoNT/A)…”
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Effects of nutritional components on aging by Lee, Dongyeop, Hwang, Wooseon, Artan, Murat, Jeong, Dae‐Eun, Lee, Seung‐Jae

“…Summary Nutrients including carbohydrates, proteins, lipids, vitamins, and minerals regulate various physiological processes and are essential for the survival…”
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RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans by Son, Heehwa G., Seo, Mihwa, Ham, Seokjin, Hwang, Wooseon, Lee, Dongyeop, An, Seon Woo A., Artan, Murat, Seo, Keunhee, Kaletsky, Rachel, Arey, Rachel N., Ryu, Youngjae, Ha, Chang Man, Kim, Yoon Ki, Murphy, Coleen T., Roh, Tae-Young, Nam, Hong Gil, Lee, Seung-Jae V.

“…Long-lived organisms often feature more stringent protein and DNA quality control. However, whether RNA quality control mechanisms, such as nonsense-mediated…”
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Genetic inhibition of an ATP synthase subunit extends lifespan in C. elegans by Xu, Chen, Hwang, Wooseon, Jeong, Dae-Eun, Ryu, Youngjae, Ha, Chang Man, Lee, Seung-Jae V., Liu, Lulu, He, Zhi Ming

“…Mild inhibition of mitochondrial respiration leads to longevity. Disruption of mitochondrial respiratory components extends lifespan in Caenorhabditis elegans…”
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RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling in Caenorhabditis elegans by Seo, Mihwa, Seo, Keunhee, Hwang, Wooseon, Koo, Hee Jung, Hahm, Jeong-Hoon, Yang, Jae-Seong, Han, Seong Kyu, Hwang, Daehee, Kim, Sanguk, Jang, Sung Key, Lee, Yoontae, Nam, Hong Gil, Lee, Seung-Jae V

“…The homeostatic maintenance of the genomic DNA is crucial for regulating aging processes. However, the role of RNA homeostasis in aging processes remains…”
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Inhibition of elongin C promotes longevity and protein homeostasis via HIF‐1 in C. elegans by Hwang, Wooseon, Artan, Murat, Seo, Mihwa, Lee, Dongyeop, Nam, Hong Gil, Lee, Seung‐Jae V.

“…Summary The transcription factor hypoxia‐inducible factor 1 (HIF‐1) is crucial for responses to low oxygen and promotes longevity in Caenorhabditis elegans. We…”
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KIN‐4/MAST kinase promotes PTEN‐mediated longevity of Caenorhabditis elegans via binding through a PDZ domain by An, Seon Woo A., Choi, Eun‐Seok, Hwang, Wooseon, Son, Heehwa G., Yang, Jae‐Seong, Seo, Keunhee, Nam, Hyun‐Jun, Nguyen, Nhung T. H., Kim, Eun Ji E., Suh, Bo Kyoung, Kim, Youngran, Nakano, Shunji, Ryu, Youngjae, Man Ha, Chang, Mori, Ikue, Park, Sang Ki, Yoo, Joo‐Yeon, Kim, Sanguk, Lee, Seung‐Jae V.

“…PDZ domain‐containing proteins (PDZ proteins) act as scaffolds for protein–protein interactions and are crucial for a variety of signal transduction processes…”
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RNAi targeting Caenorhabditis elegans α-arrestins has small or no effects on lifespan [version 2; peer review: 2 approved, 1 approved with reservations] by Park, Sangsoon, Jung, Yoonji, An, Seon Woo A, Son, Heehwa G, Hwang, Wooseon, Lee, Dongyeop, Artan, Murat, Park, Hae-Eun H, Jeong, Dae-Eun, Lee, Yujin, Lee, Seung-Jae V

“…Background: α-arrestins are a family of proteins that are implicated in multiple biological processes, including metabolism and receptor desensitization…”
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RNAi targeting Caenorhabditis elegans α-arrestins has little effect on lifespan [version 4; peer review: 3 approved] by Park, Sangsoon, Jung, Yoonji, An, Seon Woo A, Son, Heehwa G, Hwang, Wooseon, Lee, Dongyeop, Artan, Murat, Park, Hae-Eun H, Jeong, Dae-Eun, Lee, Yujin, Lee, Seung-Jae V

“…Background: α-arrestins are a family of proteins that are implicated in multiple biological processes, including metabolism and receptor desensitization…”
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Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP-mediated feedforward loop by Lee, Yujin, Jung, Yoonji, Jeong, Dae-Eun, Hwang, Wooseon, Ham, Seokjin, Park, Hae-Eun H, Kwon, Sujeong, Ashraf, Jasmine M, Murphy, Coleen T, Lee, Seung-Jae V

“…A hallmark of aging is immunosenescence, a decline in immune functions, which appeared to be inevitable in living organisms, including Caenorhabditis elegans…”
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Mitochondrial chaperone HSP‐60 regulates anti‐bacterial immunity via p38 MAP kinase signaling by Jeong, Dae‐Eun, Lee, Dongyeop, Hwang, Sun‐Young, Lee, Yujin, Lee, Jee‐Eun, Seo, Mihwa, Hwang, Wooseon, Seo, Keunhee, Hwang, Ara B, Artan, Murat, Son, Heehwa G, Jo, Jay‐Hyun, Baek, Haeshim, Oh, Young Min, Ryu, Youngjae, Kim, Hyung‐Jun, Ha, Chang Man, Yoo, Joo‐Yeon, Lee, Seung‐Jae V

“…Mitochondria play key roles in cellular immunity. How mitochondria contribute to organismal immunity remains poorly understood. Here, we show that…”
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Caenorhabditis elegans Lipin 1 moderates the lifespan‐shortening effects of dietary glucose by maintaining ω‐6 polyunsaturated fatty acids by Jung, Yoonji, Kwon, Sujeong, Ham, Seokjin, Lee, Dongyeop, Park, Hae‐Eun H., Yamaoka, Yasuyo, Jeong, Dae‐Eun, Artan, Murat, Altintas, Ozlem, Park, Sangsoon, Hwang, Wooseon, Lee, Yujin, Son, Heehwa G., An, Seon Woo A., Kim, Eun Ji E., Seo, Mihwa, Lee, Seung‐Jae V.

“…Excessive glucose causes various diseases and decreases lifespan by altering metabolic processes, but underlying mechanisms remain incompletely understood…”
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Inverse correlation between longevity and developmental rate among wild C. elegans strains by Lee, Yujin, Hwang, Wooseon, Jung, Juyoung, Park, Sangsoon, Cabatbat, Josephine Jill T, Kim, Pan-Jun, Lee, Seung-Jae V

“…Genetic studies using model organisms have shown that many long-lived mutants display impaired fitness, such as reduced fecundity and delayed development…”
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RNA helicase HEL-1 promotes longevity by specifically activating DAF-16/FOXO transcription factor signaling inCaenorhabditis elegans by Seo, Mihwa, Seo, Keunhee, Hwang, Wooseon, Koo, Hee Jung, Hahm, Jeong-Hoon, Yang, Jae-Seong, Han, Seong Kyu, Hwang, Daehee, Kim, Sanguk, Jang, Sung Key, Lee, Yoontae, Nam, Hong Gil, Lee, Seung-Jae V.

“…The homeostatic maintenance of the genomic DNA is crucial for regulating aging processes. However, the role of RNA homeostasis in aging processes remains…”
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MON-2, a Golgi protein, mediates autophagy-dependent longevity in Caenorhabditis elegans by Jung, Yoonji, Artan, Murat, Kim, Nari, Yeom, Jeonghun, Hwang, Ara B, Jeong, Dae-Eun, Altintas, Özlem, Seo, Keunhee, Seo, Mihwa, Lee, Dongyeop, Hwang, Wooseon, Lee, Yujin, Sohn, Jooyeon, Kim, Eun Ji E, Ju, Sungeun, Han, Seong Kyu, Nam, Hyun-Jun, Adams, Linnea, Ryu, Youngjae, Moon, Dong Jin, Kang, Chanhee, Yoo, Joo-Yeon, Park, Sang Ki, Ha, Chang Man, Hansen, Malene, Kim, Sanguk, Lee, Cheolju, Park, Seung-Yeol, Lee, Seung-Jae V

“…The Golgi apparatus plays a central role in trafficking cargoes such as proteins and lipids. Defects in the Golgi apparatus lead to various diseases, but its…”
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RNAi targeting Caenorhabditis elegans α-arrestins marginally affects lifespan [version 1; peer review: 2 approved with reservations] by Park, Sangsoon, Jung, Yoonji, An, Seon Woo A, Son, Heehwa G, Hwang, Wooseon, Lee, Dongyeop, Artan, Murat, Park, Hae-Eun H, Jeong, Dae-Eun, Lee, Yujin, Lee, Seung-Jae V

“…Background: α-arrestins are a family of proteins that are implicated in multiple biological processes, including metabolism and receptor desensitization…”
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RNAi targeting Caenorhabditis elegans α-arrestins has little effect on lifespan by Park, Sangsoon, Jung, Yoonji, An, Seon Woo A, Son, Heehwa G, Hwang, Wooseon, Lee, Dongyeop, Artan, Murat, Park, Hae-Eun H, Jeong, Dae-Eun, Lee, Yujin, Lee, Seung-Jae V

“…α-arrestins are a family of proteins that are implicated in multiple biological processes, including metabolism and receptor desensitization. Here, we sought…”
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