Search Results - "Hwang, Sunyoung"
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Quantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast
Published in eLife (29-07-2014)“…Aneuploidy causes severe developmental defects and is a near universal feature of tumor cells. Despite its profound effects, the cellular processes affected by…”
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2
SDE2 integrates into the TIMELESS-TIPIN complex to protect stalled replication forks
Published in Nature communications (30-10-2020)“…Protecting replication fork integrity during DNA replication is essential for maintaining genome stability. Here, we report that SDE2, a PCNA-associated…”
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3
Regulation of oxidative stress response by CosR, an essential response regulator in Campylobacter jejuni
Published in PloS one (19-07-2011)“…CosR (Campylobacter oxidative stress regulator; Cj0355c) is an OmpR-type response regulator essential for the viability of Campylobacter jejuni, a leading…”
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Transcriptional Regulation of the CmeABC Multidrug Efflux Pump and the KatA Catalase by CosR in Campylobacter jejuni
Published in Journal of Bacteriology (01-12-2012)“…CosR is an essential response regulator in Campylobacter jejuni, a major food-borne pathogen causing enteritis worldwide. A transcriptomic analysis performed…”
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ATAD5 promotes replication restart by regulating RAD51 and PCNA in response to replication stress
Published in Nature communications (16-12-2019)“…Maintaining stability of replication forks is important for genomic integrity. However, it is not clear how replisome proteins contribute to fork stability…”
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Outer Membrane Proteins A (OmpA) and X (OmpX) Are Essential for Basolateral Invasion of Cronobacter sakazakii
Published in Applied and Environmental Microbiology (01-08-2010)“…Cronobacter sakazakii is an opportunistic pathogen that actively invades host eukaryotic cells. To identify invasion factors responsible for the intestinal…”
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7
Suppressing Aneuploidy-Associated Phenotypes Improves the Fitness of Trisomy 21 Cells
Published in Cell reports (Cambridge) (19-11-2019)“…An abnormal number of chromosomes, or aneuploidy, accounts for most spontaneous abortions, causes developmental defects, and is associated with aging and…”
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Combining Human Umbilical Cord Blood Cells With Erythropoietin Enhances Angiogenesis/Neurogenesis and Behavioral Recovery After Stroke
Published in Frontiers in neurology (10-04-2019)“…Disruption of blood flow in the brain induces stroke, the leading cause of death and disability worldwide. However, so far the therapeutic options are limited…”
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CosR Regulation of perR Transcription for the Control of Oxidative Stress Defense in Campylobacter jejuni
Published in Microorganisms (Basel) (11-06-2021)“…Oxidative stress resistance is an important mechanism to sustain the viability of oxygen-sensitive microaerophilic Campylobacter jejuni. In C. jejuni, gene…”
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10
PCNA Unloading Is Negatively Regulated by BET Proteins
Published in Cell reports (Cambridge) (24-12-2019)“…Proliferating cell nuclear antigen (PCNA) is a DNA clamp essential for DNA replication. During DNA synthesis, PCNA is continuously loaded onto and unloaded…”
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Transducer-Like Protein in Campylobacter jejuni With a Role in Mediating Chemotaxis to Iron and Phosphate
Published in Frontiers in microbiology (16-11-2018)“…Chemotaxis-mediated motility enables to navigate through complex environmental gradients and colonize diverse niches. is known to possess several methyl…”
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12
Regulation of perR Expression by Iron and PerR in Campylobacter jejuni
Published in Journal of Bacteriology (01-11-2011)“…Campylobacter jejuni is a leading food-borne pathogen causing gastroenteritis in humans. Although OxyR is a widespread oxidative stress regulator in many…”
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13
Reliability of behavioral tests in the middle cerebral artery occlusion model of rat
Published in Laboratory animals (London) (01-10-2019)“…Stroke is one of the leading causes of death and disability worldwide, and its incidence is increasing. To overcome impairment from stroke, translational…”
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14
Roles of the superoxide dismutase SodB and the catalase KatA in the antibiotic resistance of Campylobacter jejuni
Published in Journal of antibiotics (01-06-2013)Get full text
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15
Neuroprotective Effect of Ghrelin in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson’s Disease by Blocking Microglial Activation
Published in Neurotoxicity research (01-05-2009)“…Ghrelin is an endogenous ligand for growth hormone (GH) secretagogue receptor 1a (GHS-R1a) and is produced and released mainly from the stomach. It was…”
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Roles of RpoN in the resistance of Campylobacter jejuni under various stress conditions
Published in BMC microbiology (22-09-2011)“…Campylobacter jejuni is a leading foodborne pathogen worldwide. Despite the fastidious nature of C. jejuni growth, increasing numbers of human…”
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RAD51 separation of function mutation disables replication fork maintenance but preserves DSB repair
Published in iScience (19-04-2024)“…Homologous recombination (HR) protects replication forks (RFs) and repairs DNA double-strand breaks (DSBs). Within HR, BRCA2 regulates RAD51 via two…”
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Divergent distribution of the sensor kinase CosS in non-thermotolerant campylobacter species and its functional incompatibility with the response regulator CosR of Campylobacter jejuni
Published in PloS one (28-02-2014)“…Two-component signal transduction systems are commonly composed of a sensor histidine kinase and a cognate response regulator, modulating gene expression in…”
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19
Threat-induced autonomic dysregulation in panic disorder evidenced by heart rate variability measures
Published in General hospital psychiatry (01-09-2013)“…Abstract Objective The objective was to compare autonomic response to threatening stimuli between patients with panic disorder (PD) and healthy volunteers by…”
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Neuroprotective Effect of Ghrelin Is Associated with Decreased Expression of Prostate Apoptosis Response-4
Published in Endocrine Journal (2009)“…Ghrelin is known to promote neuronal defense and survival against ischemic injury by inhibiting apoptotic processes. In the present study, we investigated the…”
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