Search Results - "Hwang, Soon B"

Identification of African Swine Fever Virus Inhibitors through High Performance Virtual Screening Using Machine Learning by Choi, Jiwon, Tark, Dongseob, Lim, Yun-Sook, Hwang, Soon B

“…African swine fever virus (ASFV) is a highly contagious virus that causes severe hemorrhagic viral disease resulting in high mortality in domestic and wild…”
Get full text

A natural product YSK-A blocks SARS-CoV-2 propagation by targeting multiple host genes by Pham, Thuy X., Huynh, Trang T. X., Kim, Bumseok, Lim, Yun-Sook, Hwang, Soon B.

“…Natural products and herbal medicine have been widely used in drug discovery for treating infectious diseases. Recent outbreak of COVID-19 requires various…”
Get full text

Hepatitis C Virus Downregulates Ubiquitin-Conjugating Enzyme E2S Expression To Prevent Proteasomal Degradation of NS5A, Leading to Host Cells More Sensitive to DNA Damage by Pham, Hang T, Nguyen, Tram T T, Nguyen, Lap P, Han, Sang-Seop, Lim, Yun-Sook, Hwang, Soon B

“…Hepatitis C virus (HCV) infection may cause chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. HCV exploits cellular machineries to establish…”
Get full text

Hepatitis C Virus Nonstructural 4B Protein Modulates Sterol Regulatory Element-binding Protein Signaling via the AKT Pathway by Park, Chul-Yong, Jun, Hyun-Jeong, Wakita, Takaji, Cheong, Jae Hun, Hwang, Soon B.

“…Hepatitis C virus (HCV) infection is often associated with hepatic steatosis and yet the molecular mechanisms of HCV-associated steatosis are poorly…”
Get full text

Hepatitis C Virus Modulates Solute carrier family 3 member 2 for Viral Propagation by Nguyen, Ngan N. T., Lim, Yun-Sook, Nguyen, Lap P., Tran, Si C., Luong, Trang T. D., Nguyen, Tram T. T., Pham, Hang T., Mai, Han N., Choi, Jae-Woong, Han, Sang-Seop, Hwang, Soon B.

“…Hepatitis C virus (HCV) exploits an extensive network of host proteins to maintain chronic infection. Using RNA-Seq technology, we identified 30 host genes…”
Get full text

Asunaprevir, a Potent Hepatitis C Virus Protease Inhibitor, Blocks SARS-CoV-2 Propagation by Lim, Yun-Sook, Nguyen, Lap P, Lee, Gun-Hee, Lee, Sung-Geun, Lyoo, Kwang-Soo, Kim, Bumseok, Hwang, Soon B

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has become a global health concern. Various SARS-CoV-2 vaccines have been developed…”
Get full text

Hepatitis C Virus Nonstructural Protein 5A Interacts with Immunomodulatory Kinase IKKε to Negatively Regulate Innate Antiviral Immunity by Kang, Sang-Min, Park, Ji-Young, Han, Hee-Jeong, Song, Byeong-Min, Tark, Dongseob, Choi, Byeong-Sun, Hwang, Soon B

“…Hepatitis C virus (HCV) infection can lead to chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. HCV employs diverse strategies to evade host…”
Get full text

Hepatitis C Virus-Induced Rab32 Aggregation and Its Implications for Virion Assembly by Pham, Tu M, Tran, Si C, Lim, Yun-Sook, Hwang, Soon B

“…Hepatitis C virus (HCV) is highly dependent on cellular factors for viral propagation. Using high-throughput next-generation sequencing, we analyzed the host…”
Get full text

The ribonuclease l-dependent antiviral roles of human 2′,5′-oligoadenylate synthetase family members against hepatitis C virus by Kwon, Young-Chan, Kang, Ju-Il, Hwang, Soon B., Ahn, Byung-Yoon

“…► Expression of the ribonuclease RNase L inhibited HCV replication in Huh7 cells. ► Ectopic expression of the OAS1 p46 and OAS3 p100 activated the RNase L. ►…”
Get full text

Prediction of African Swine Fever Virus Inhibitors by Molecular Docking-Driven Machine Learning Models by Choi, Jiwon, Yun, Jun Seop, Song, Hyeeun, Shin, Yong-Keol, Kang, Young-Hoon, Munashingha, Palinda Ruvan, Yoon, Jeongyeon, Kim, Nam Hee, Kim, Hyun Sil, Yook, Jong In, Tark, Dongseob, Lim, Yun-Sook, Hwang, Soon B

“…African swine fever virus (ASFV) causes a highly contagious and severe hemorrhagic viral disease with high mortality in domestic pigs of all ages. Although the…”
Get full text

Hepatitis C Virus Nonstructural 5A Protein Interacts with Telomere Length Regulation Protein: Implications for Telomere Shortening in Patients Infected with HCV by Lim, Yun-Sook, Nguyen, Men T N, Pham, Thuy X, Huynh, Trang T X, Park, Eun-Mee, Choi, Dong Hwa, Kang, Sang Min, Tark, Dongseob, Hwang, Soon B

“…Hepatitis C virus (HCV) is a major cause of chronic liver disease and is highly dependent on cellular proteins for viral propagation. Using protein microarray…”
Get full text

Nonstructural NS5A Protein Regulates LIM and SH3 Domain Protein 1 to Promote Hepatitis C Virus Propagation by Choi, Jae-Woong, Kim, Jong-Wook, Nguyen, Lap P, Nguyen, Huu C, Park, Eun-Mee, Choi, Dong Hwa, Han, Kang Min, Kang, Sang Min, Tark, Dongseob, Lim, Yun-Sook, Hwang, Soon B

“…Hepatitis C virus (HCV) propagation is highly dependent on cellular proteins. To identify the host factors involved in HCV propagation, we previously performed…”
Get full text

Peptidyl-Prolyl Isomerase Pin1 Is a Cellular Factor Required for Hepatitis C Virus Propagation by LIM, Yun-Sook, TRAN, Huong T. L, PARK, Soo-Je, YIM, Seung-Ae, HWANG, Soon B

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Adenosylhomocysteinase like 1 interacts with nonstructural 5A and regulates hepatitis C virus propagation by Lim, Yun-Sook, Mai, Han N., Nguyen, Lap P., Kang, Sang Min, Tark, Dongseob, Hwang, Soon B.

“…Hepatitis C virus (HCV) life cycle is highly dependent on cellular proteins for viral propagation. In order to identify the cellular factors involved in HCV…”
Get full text

Nonstructural 3 Protein of Hepatitis C Virus Modulates the Tribbles Homolog 3/Akt Signaling Pathway for Persistent Viral Infection by Tran, Si C, Pham, Tu M, Nguyen, Lam N, Park, Eun-Mee, Lim, Yun-Sook, Hwang, Soon B

“…Hepatitis C virus (HCV) infection often causes chronic hepatitis, liver cirrhosis, and ultimately hepatocellular carcinoma. However, the mechanisms underlying…”
Get full text

5-Oxo-1-[(2,3,6,7-tetramethoxy-9-phenanthrenyl)methyl]-L-proline Inhibits Hepatitis C Virus Entry by Nguyen, Lap P., Park, Chorong, Luong, Trang T. D., Park, Eun-Mee, Choi, Dong-Hwa, Han, Kang Min, Mai, Han N., Nguyen, Huu C., Lim, Yun-Sook, Hwang, Soon B.

“…Hepatitis C virus (HCV) is the major causative agent of chronic liver diseases, including liver cirrhosis and hepatocellular carcinoma. The recent development…”
Get full text

AAM-B Interacts with Nonstructural 4B and Regulates Hepatitis C Virus Propagation by Park, Eun-Mee, Lim, Yun-Sook, Ahn, Byung-Yoon, Hwang, Soon B

“…Hepatitis C virus (HCV) usurps host cellular lipid metabolism for production of infectious virus particles. Recently, we have screened a siRNA library…”
Get full text

Farnesyl-diphosphate farnesyltransferase 1 regulates hepatitis C virus propagation by Park, Eun-Mee, Nguyen, Lam N., Lim, Yun-Sook, Hwang, Soon B.

“…•We identified farnesyl-diphosphate farnesyltransferase 1 (FDFT1) as a host factor involved in HCV propagation.•Silencing of FDFT1 impaired HCV propagation in…”
Get full text

Abl Tyrosine Kinase Regulates Hepatitis C Virus Entry by Min, Saehong, Lim, Yun-Sook, Shin, Dongjo, Park, Chorong, Park, Jae-Bong, Kim, Seungtaek, Windisch, Marc P, Hwang, Soon B

“…Abl is a central regulator of multiple cellular processes controlling actin dynamics, proliferation, and differentiation. Here, we showed that knockdown of Abl…”
Get full text

Hepatitis C Virus Exploits Death Receptor 6-mediated Signaling Pathway to Facilitate Viral Propagation by Luong, Trang T. D., Tran, Giao V. Q., Shin, Dong-Jo, Lim, Yun-Sook, Hwang, Soon B.

“…The life cycle of hepatitis C virus (HCV) is highly dependent on host proteins for virus propagation. By transcriptome sequencing analysis, we identified host…”
Get full text