Search Results - "Hwang, Soo Seok"

Emerging role of anti-proliferative protein BTG1 and BTG2 by Kim, Sang Hyeon, Jung, In Ryeong, Hwang, Soo Seok

“…The B cell translocation gene 1 (BTG1) and BTG2 play a key role in a wide range of cellular activities including proliferation, apoptosis, and cell growth via…”
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Discussion: Adipose-Derived Stem Cell Extracellular Vesicles Improve Wound Closure and Angiogenesis in Diabetic Mice by Kim, Bong-Sung, Hwang, Soo-Seok, Kao, Huang-Kai

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PTEN drives Th17 cell differentiation by preventing IL-2 production by Kim, Hyeong Su, Jang, Sung Woong, Lee, Wonyong, Kim, Kiwan, Sohn, Hyogon, Hwang, Soo Seok, Lee, Gap Ryol

“…T helper 17 (Th17) cells are a CD4 T cell subset that produces IL-17A to mediate inflammation and autoimmunity. IL-2 inhibits Th17 cell differentiation…”
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YY1 inhibits differentiation and function of regulatory T cells by blocking Foxp3 expression and activity by Hwang, Soo Seok, Jang, Sung Woong, Kim, Min Kyung, Kim, Lark Kyun, Kim, Bong-Sung, Kim, Hyeong Su, Kim, Kiwan, Lee, Wonyong, Flavell, Richard A., Lee, Gap Ryol

“…Regulatory T (T reg ) cells are essential for maintenance of immune homeostasis. Foxp3 is the key transcription factor for T reg -cell differentiation and…”
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Distinct adaptive mechanisms drive recovery from aneuploidy caused by loss of the Ulp2 SUMO protease by Ryu, Hong-Yeoul, López-Giráldez, Francesc, Knight, James, Hwang, Soo Seok, Renner, Christina, Kreft, Stefan G., Hochstrasser, Mark

“…In response to acute loss of the Ulp2 SUMO-specific protease, yeast become disomic for chromosome I (ChrI) and ChrXII. Here we report that ChrI disomy, which…”
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RNA Metabolism in T Lymphocytes by Choi, Jin Ouk, Ham, Jeong Hyeon, Hwang, Soo Seok

“…RNA metabolism plays a central role in regulating of T cell-mediated immunity. RNA processing, modifications, and regulations of RNA decay influence the tight…”
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Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation by Hwang, Soo Seok, Kim, Young Uk, Lee, Sumin, Jang, Sung Woong, Kim, Min Kyung, Koh, Byung Hee, Lee, Wonyong, Kim, Joomyeong, Souabni, Abdallah, Busslinger, Meinrad, Lee, Gap Ryol

“…The Th2 locus control region (LCR) has been shown to be important in efficient and coordinated cytokine gene regulation during Th2 cell differentiation…”
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Th2 LCR is essential for regulation of Th2 cytokine genes and for pathogenesis of allergic asthma by Koh, Byung Hee, Hwang, Soo Seok, Kim, Joo Young, Lee, Wonyong, Kang, Min-Jong, Lee, Chun Geun, Park, Jung-Won, Flavell, Richard A, Lee, Gap Ryol

“…Previous studies have shown that Th2 cytokine genes on mouse chromosome 11 are coordinately regulated by the Th2 locus control region (LCR). To examine the in…”
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PPARγ negatively regulates T cell activation to prevent follicular helper T cells and germinal center formation by Park, Hong-Jai, Kim, Do-Hyun, Choi, Jin-Young, Kim, Won-Ju, Kim, Ji Yun, Senejani, Alireza G, Hwang, Soo Seok, Kim, Lark Kyun, Tobiasova, Zuzana, Lee, Gap Ryol, Craft, Joseph, Bothwell, Alfred L M, Choi, Je-Min

“…Peroxisome proliferator-activated receptor gamma (PPARγ) is a transcription factor that regulates lipid and glucose metabolism. Although studies of PPARγ…”
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Epigallocatechin-3-Gallate Attenuates Myocardial Dysfunction via Inhibition of Endothelial-to-Mesenchymal Transition by Kim, Sejin, Lee, Hyunjae, Moon, Hanbyeol, Kim, Ran, Kim, Minsuk, Jeong, Seongtae, Kim, Hojin, Kim, Sang Hyeon, Hwang, Soo Seok, Lee, Min Young, Kim, Jongmin, Song, Byeong-Wook, Chang, Woochul

“…Cardiac tissue damage following ischemia leads to cardiomyocyte apoptosis and myocardial fibrosis. Epigallocatechin-3-gallate (EGCG), an active polyphenol…”
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D‐dopachrome tautomerase in adipose tissue inflammation and wound repair by Kim, Bong‐Sung, Tilstam, Pathricia V., Hwang, Soo Seok, Simons, David, Schulte, Wibke, Leng, Lin, Sauler, Maor, Ganse, Bergita, Averdunk, Luisa, Kopp, Rüdger, Stoppe, Christian, Bernhagen, Jürgen, Pallua, Norbert, Bucala, Richard

“…D‐dopachrome tautomerase (D‐DT/MIF‐2) is a member of the macrophage migration inhibitory factor (MIF) cytokine superfamily, and a close structural homolog of…”
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YinYang1 deficiency ameliorates joint inflammation in a murine model of rheumatoid arthritis by modulating Th17 cell activation by Kwon, Jeong-eun, Lee, Seon-Yeong, Seo, Hyeon-Beom, Moon, Young-Mee, Ryu, Jun-Geol, Jung, Kyung-Ah, Jhun, Joo-Yeon, Park, Jin-Sil, Hwang, Soo-Seok, Kim, Joo-Myeong, Lee, Gap Ryol, Park, Sung-Hwan, Cho, Mi-La

“…•YY1 as new target for RA therapies involved in Th17 cell differentiation. Yin Yang 1 (YY1) is a ubiquitously expressed transcription factor that functions in…”
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Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cytokine expression by Williams, Adam, Lee, Gap Ryol, Spilianakis, Charalampos G., Hwang, Soo Seok, Eisenbarth, Stephanie C., Flavell, Richard A.

“…The T helper type 2 (Th2) cytokine genes Il4 , Il5 , and Il13 are contained within a 140-kb region of mouse chromosome 11 and their expression is controlled by…”
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OSNC4: Flexural strength of CAD/CAM hybrid blocks after 2 years aging in water at 37°C by Lim, Bum-Soon, Lee, Han-Ah, Seok, Soo-Hwang, Oh, Myung-Hwan, Kang, Jong-Ho

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Characterization of adipose tissue macrophages and adipose-derived stem cells in critical wounds by Kim, Bong-Sung, Tilstam, Pathricia V, Springenberg-Jung, Katrin, Boecker, Arne Hendrick, Schmitz, Corinna, Heinrichs, Daniel, Hwang, Soo Seok, Stromps, Jan Philipp, Ganse, Bergita, Kopp, Ruedger, Knobe, Matthias, Bernhagen, Juergen, Pallua, Norbert, Bucala, Richard

“…Subcutaneous adipose tissue is a rich source of adipose tissue macrophages and adipose-derived stem cells which both play a key role in wound repair. While…”
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Emerging role of antiproliferative protein BTG1 and BTG2 by Kim, Sang Hyeon, Jung, In Ryeong, Hwang, Soo Seok

“…The B cell translocation gene 1 (BTG1) and BTG2 play a key role in a wide range of cellular activities including proliferation, apoptosis, and cell growth via…”
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mRNA destabilization by BTG1 and BTG2 maintains T cell quiescence by Hwang, Soo Seok, Lim, Jaechul, Yu, Zhibin, Kong, Philip, Sefik, Esen, Xu, Hao, Harman, Christian C D, Kim, Lark Kyun, Lee, Gap Ryol, Li, Hua-Bing, Flavell, Richard A

“…T cells maintain a quiescent state prior to activation. As inappropriate T cell activation can cause disease, T cell quiescence must be preserved. Despite its…”
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Emerging role of anti-proliferative protein BTG1 and BTG2 by Sang Hyeon Kim, In Ryeong Jung, 황수석

“…The B cell translocation gene 1 (BTG1) and BTG2 play a keyrole in a wide range of cellular activities including proliferation,apoptosis, and cell growth via…”
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The transcription factor Batf3 inhibits the differentiation of regulatory T cells in the periphery by Lee, Wonyong, Kim, Hyeong Su, Hwang, Soo Seok, Lee, Gap Ryol

“…Naive CD4 T cells activated by antigen-presenting cells (APCs) undergo terminal differentiation in the periphery. Multiple mechanisms determine their fates,…”
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Loss of the SUMO protease Ulp2 triggers a specific multichromosome aneuploidy by Ryu, Hong-Yeoul, Wilson, Nicole R, Mehta, Sameet, Hwang, Soo Seok, Hochstrasser, Mark

“…Post-translational protein modification by the small ubiquitin-related modifier (SUMO) regulates numerous cellular pathways, including transcription, cell…”
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