Search Results - "Hwang, Sejung"
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Circulating Hemocytes from Larvae of the Japanese Rhinoceros Beetle Allomyrina dichotoma (Linnaeus) (Coleoptera: Scarabaeidae) and the Cellular Immune Response to Microorganisms
Published in PloS one (01-06-2015)“…Hemocytes of the last larva of the Japanese rhinoceros beetle A. dichotoma (Linnaeus) (Coleoptera: Scarabaeidae) were classified as granulocytes,…”
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2
Pharmacokinetic drug–drug interactions of JBPOS0101 mediated by cytochrome P450 3A4 and UDP‐glucuronosyltransferases
Published in Clinical and translational science (01-07-2024)“…JBPOS0101 is a new antiepileptic drug and is a substrate of UDP‐glucuronosyltransferases (UGTs) in in vitro test. In vitro experiments showed different results…”
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3
Infection-induced molecular pattern recognition proteins in larvae of Protaetia brevitarsis seulensis (Coleoptera: Cetoniidae)
Published in European journal of entomology (01-01-2022)“…We cloned and sequenced full-length peptidoglycan recognition protein (PGRP)-like cDNAs, named PS PGRP-SA(a)-like, PS PGRP-SA(b)-like, PS PGRP-SBI-like and PS…”
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4
Identification and characterization of Furins in larvae of Protaetia brevitarsis seulensis (Kolbe) (Coleoptera: Cetoniidae)
Published in Journal of Asia-Pacific entomology (01-08-2021)“…[Display omitted] •The furins from larvae of Protaetia brevitarsis seulensis are isolated and characterized.•Expression of Psfurin-1 mRNA is highly…”
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5
Use of powdered immunized insects for inhibiting Pectobacterium carotovorum infestation and promoting growth in lettuce
Published in European journal of entomology (01-01-2024)“…We induced immune activation in mass rearing experiments in three insect species, i.e., Gryllus bimaculatus De Geer, 1773 (Orthoptera: Gryllidae), Hermetia…”
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Estimation of the benefit from pre‐emptive genotyping based on the nationwide cohort data in South Korea
Published in Clinical and translational science (01-03-2024)“…Genetic variants affect drug responses, making pre‐emptive genotyping crucial for averting serious adverse events (SAEs) and treatment failure. However,…”
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Co-Administration of Vonoprazan, Not Tegoprazan, Affects the Pharmacokinetics of Atorvastatin in Healthy Male Subjects
Published in Frontiers in pharmacology (11-11-2021)“…Potassium-competitive acid blocker is a new class of drugs inhibiting gastric acid. It is controversial that vonoprazan showed the inhibitory activities of…”
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The pharmacokinetic, safety, and tolerability profiles of eslicarbazepine acetate are comparable between Korean and White subjects
Published in Clinical and translational science (01-09-2022)“…Eslicarbazepine acetate (ESL) is a prodrug antiseizure medication for the treatment of focal seizures. ESL shows a well‐established pharmacokinetic…”
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Adaptive design clinical trials: current status by disease and trial phase in various perspectives
Published in Translational and clinical pharmacology (01-12-2023)“…An adaptive design is a clinical trial design that allows for modification of a structured plan in a clinical trial based on data accumulated during…”
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Quantification of OATP1B1 endogenous metabolites coproporphyrin I and III in human urine
Published in Translational and clinical pharmacology (01-09-2023)“…Coproporphyrin (CP)-I and CP-III are the markers of organic anion-transporting polypeptides’ (OATPs) activities, and they are porphyrin metabolites that…”
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Immune tolerance to an intestine-adapted bacteria, Chryseobacterium sp., injected into the hemocoel of Protaetia brevitarsis seulensis
Published in Scientific reports (17-08-2016)“…To explore the interaction of gut microbes and the host immune system, bacteria were isolated from the gut of Protaetia brevitarsis seulensis larvae…”
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Comprehensive Evaluation of OATP‐ and BCRP‐Mediated Drug–Drug Interactions of Methotrexate Using Physiologically‐Based Pharmacokinetic Modeling
Published in Clinical pharmacology and therapeutics (01-10-2024)“…Methotrexate (MTX) is an antifolate agent widely used for treating conditions such as rheumatoid arthritis and hematologic cancer. This study aimed to…”
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Population Pharmacokinetic-Pharmacodynamic Modeling of Carvedilol to Evaluate the Effect of Cytochrome P450 2D6 Genotype on the Heart Rate Reduction
Published in Journal of Korean medical science (05-06-2023)“…Carvedilol is a beta-adrenergic receptor antagonist primarily metabolized by cytochromes P450 (CYP) 2D6. This study established a carvedilol population…”
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14
cDNA cloning and molecular characterization of a defensin-like antimicrobial peptide from larvae of Protaetia brevitarsis seulensis (Kolbe)
Published in Molecular biology reports (01-05-2016)“…We identified new defensin-like cDNA (called Psdefensin) by searching data set of high-throughput RNA sequencing (RNA-seq) expression profiling of immunized…”
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Identification of immunity-related genes in the larvae of Protaetia brevitarsis seulensis (Coleoptera: Cetoniidae) by a next-generation sequencing-based transcriptome analysis
Published in Journal of insect science (Tucson, Ariz.) (2015)“…To identify immune-related genes in the larvae of white-spotted flower chafers, next-generation sequencing was conducted with an Illumina HiSeq2000, resulting…”
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Evaluation of Vancomycin TDM Strategies: Prediction and Prevention of Kidney Injuries Based on Vancomycin TDM Results
Published in Journal of Korean medical science (10-04-2023)“…The current guidelines for therapeutic drug monitoring (TDM) of vancomycin suggest a target 24-hour area under the curve (AUC ) of 400 to 600 mg*h/L for…”
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Effect of Food on the Pharmacokinetics and Pharmacodynamics of a Novel Dual Delayed‐Release Formulation of Esomeprazole in Healthy Subjects
Published in Clinical pharmacology in drug development (01-08-2023)“…A novel dual delayed‐release formulation (DR) of esomeprazole was developed to prolong the effect of esomeprazole inhibiting gastric acid secretion. This study…”
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Pharmacokinetics, Tolerability and Pharmacogenetics of DA-8031 After Multiple Ascending Doses in Healthy Male Subjects
Published in Drug design, development and therapy (01-01-2021)“…DA-8031 is a novel selective serotonin reuptake inhibitor for the treatment of premature ejaculation. This study investigated the pharmacokinetics, safety and…”
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Population Pharmacokinetic Modelling and Simulation to Determine the Optimal Dose of Nanoparticulated Sorafenib to the Reference Sorafenib
Published in Pharmaceutics (28-04-2021)“…Sorafenib, an oral multikinase inhibitor, exhibits a highly variable absorption profile due to enterohepatic reabsorption and poor solubility. SYO-1644…”
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Circulating Hemocytes from Larvae of the Japanese Rhinoceros Beetle Allomyrina dichotoma (Linnaeus) (Coleoptera: Scarabaeidae) and the Cellular Immune Response to Microorganisms: e0128519
Published in PloS one (01-06-2015)“…Hemocytes of the last larva of the Japanese rhinoceros beetle A. dichotoma (Linnaeus) (Coleoptera: Scarabaeidae) were classified as granulocytes,…”
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