Search Results - "Hwang, Jungwook"

Role of UPF1-LIN28A interaction during early differentiation of pluripotent stem cells by Jung, Seungwon, Ko, Seung Hwan, Ahn, Narae, Lee, Jinsam, Park, Chang-Hwan, Hwang, Jungwook

“…UPF1 and LIN28A are RNA-binding proteins involved in post-transcriptional regulation and stem cell differentiation. Most studies on UPF1 and LIN28A have…”
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UPF1/SMG7-dependent microRNA-mediated gene regulation by Park, Jungyun, Seo, Jwa-Won, Ahn, Narae, Park, Seokju, Hwang, Jungwook, Nam, Jin-Wu

“…The stability and quality of metazoan mRNAs are under microRNA (miRNA)-mediated and nonsense-mediated control. Although UPF1, a core mediator of…”
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Role of UPF1 in lncRNA-HEIH regulation for hepatocellular carcinoma therapy by Cha, Hyunho, Kim, Minwoo, Ahn, Narae, Jeong, Seong Dong, Ignatova, Elizaveta, Chi, Sung Wook, Kim, Hyeon Ho, Hwang, Jungwook

“…UPF1, a novel posttranscriptional regulator, regulates the abundance of transcripts, including long noncoding RNAs (lncRNAs), and thus plays an important role…”
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Clearance of Damaged Mitochondria Through PINK1 Stabilization by JNK and ERK MAPK Signaling in Chlorpyrifos-Treated Neuroblastoma Cells by Park, Jae Hyeon, Ko, Juyeon, Park, Yun Sun, Park, Jungyun, Hwang, Jungwook, Koh, Hyun Chul

“…Mitochondrial quality control and clearance of damaged mitochondria through mitophagy are important cellular activities. Studies have shown that PTEN-induced…”
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Auranofin prevents liver fibrosis by system Xc-mediated inhibition of NLRP3 inflammasome by Kim, Hyun Young, Choi, Young Jae, Kim, Sang Kyum, Kim, Hyunsung, Jun, Dae Won, Yoon, Kyungrok, Kim, Nayoun, Hwang, Jungwook, Kim, Young-Mi, Lim, Sung Chul, Kang, Keon Wook

“…Demand for a cure of liver fibrosis is rising with its increasing morbidity and mortality. Therefore, it is an urgent issue to investigate its therapeutic…”
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Simultaneous Determination of Multiple microRNA Levels Utilizing Biotinylated Dideoxynucleotides and Mass Spectrometry by Kim, Sobin, Park, Jungyun, Na, Jeongkyeong, Jung, Gyoo Yeol, Hwang, Jungwook

“…MicroRNAs (miRNAs) are important regulators of gene translation and have been suggested as potent biomarkers in various disease states. In this study, we…”
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CK2-mediated TEL2 phosphorylation augments nonsense-mediated mRNA decay (NMD) by increase of SMG1 stability by Ahn, Seyoung, Kim, Jinyoung, Hwang, Jungwook

“…Nonsense-mediated mRNA decay (NMD) is the best-characterized mRNA surveillance mechanism that degrades a premature-termination codon (PTC)-containing mRNA…”
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A Phase 2a, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy and Safety of ALS-L1023 in Non-Alcoholic Fatty Liver Disease by Kim, Gi-Ae, Cho, Hyun Chin, Jeong, Soung Won, Kang, Bo-Kyeong, Kim, Mimi, Jung, Seungwon, Hwang, Jungwook, Yoon, Eileen L, Jun, Dae Won

“…Preclinical data have shown that the herbal extract, ALS-L1023, from reduces visceral fat and hepatic steatosis. We aimed to assess the safety and efficacy of…”
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Discovery of dipeptidyl peptidase-4 inhibitor specific biomarker in non-alcoholic fatty liver disease mouse models using modified basket trial by Oh, Ju Hee, Jun, Dae Won, Kim, Hye Young, Lee, Seung Min, Yoon, Eileen L., Hwang, Jungwook, Park, Jung Hwan, Lee, Hanbi, Kim, Wankyu, Kim, Hyunsung

“…Background/Aims: We aimed to define an optimal target population and drug-specific biomarkers that may predict dipeptidyl peptidase (DPP)-4 inhibitor responses…”
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Hepatitis C Virus Nonstructural Protein 5A: Biochemical Characterization of a Novel Structural Class of RNA-Binding Proteins by HWANG, Jungwook, LUYUN HUANG, CORDEK, Daniel G, VAUGHAN, Robert, REYNOLDS, Shelley L, KIHARA, George, RANEY, Kevin D, CHENG KAO, C, CAMERON, Craig E

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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UPF1 Inhibits Hepatocellular Carcinoma Growth through DUSP1/p53 Signal Pathway by Lee, Suman, Hwang, Yukyung, Kim, Tae Hun, Jeong, Jaemin, Choi, Dongho, Hwang, Jungwook

“…Human hepatocellular carcinoma (HCC) has a high mortality rate because of the dearth of effective treatments. Multiple studies have shown that overexpression…”
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Hepatitis C Virus Nonstructural Protein 5A (NS5A) Is an RNA-binding Protein by Huang, Luyun, Hwang, Jungwook, Sharma, Suresh D., Hargittai, Michele R.S., Chen, Yingfeng, Arnold, Jamie J., Raney, Kevin D., Cameron, Craig E.

“…Hepatitis C virus (HCV) nonstructural protein 5A (NS5A) has been shown to antagonize numerous cellular pathways, including the antiviral interferon-α response…”
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When a ribosome encounters a premature termination codon by Hwang, J.W., Hanyang University, Seoul, Republic of korea, Kim, Y.K., Korea University, Seoul, Republic of korea

“…In mammalian cells, aberrant transcripts harboring a premature termination codon (PTC) can be generated by abnormal or inefficient biogenesis of mRNAs or by…”
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Transient receptor potential cation channel V1 (TRPV1) is degraded by starvation- and glucocorticoid-mediated autophagy by Ahn, Seyoung, Park, Jungyun, An, Inkyung, Jung, Sung Jun, Hwang, Jungwook

“…A mammalian cell renovates itself by autophagy, a process through which cellular components are recycled to produce energy and maintain homeostasis. Recently,…”
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Expanding the Proteome of an RNA Virus by Phosphorylation of an Intrinsically Disordered Viral Protein by Cordek, Daniel G., Croom-Perez, Tayler J., Hwang, Jungwook, Hargittai, Michele R.S., Subba-Reddy, Chennareddy V., Han, Qingxia, Lodeiro, Maria Fernanda, Ning, Gang, McCrory, Thomas S., Arnold, Jamie J., Koc, Hasan, Lindenbach, Brett D., Showalter, Scott A., Cameron, Craig E.

“…The human proteome contains myriad intrinsically disordered proteins. Within intrinsically disordered proteins, polyproline-II motifs are often located near…”
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When a ribosome encounters a premature termination codon by Hwang, Jungwook, Kim, Yoon Ki

“…In mammalian cells, aberrant transcripts harboring a premature termination codon (PTC) can be generated by abnormal or inefficient biogenesis of mRNAs or by…”
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Transient Receptor Potential Cation Channel V1 (TRPV1) Is Degraded by Starvation- and Glucocorticoid-Mediated Autophagy by Ahn, Seyoung, Park, Jungyun, An, Inkyung, Jung, Sung Jun, Hwang, Jungwook

“…A mammalian cell renovates itself by autophagy, a process through which cellular components are recycled to produce energy and maintain homeostasis. Recently,…”
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Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question by Hwang, Jungwook, Maquat, Lynne E

“…Highlights ► We present EJC-dependent and faux 3′-UTR mechanisms of NMD in eukaryotes. ► We highlight embryogenesis in animals: particularly worm, fly, fish,…”
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Dynamin-related protein 1 mediates mitochondria-dependent apoptosis in chlorpyrifos-treated SH-SY5Y cells by Park, Jae Hyeon, Ko, Juyeon, Hwang, Jungwook, Koh, Hyun Chul

“…•CPF induces mitochondria apoptotic cell death in SH-SY5Y cells.•Drp1 mediates mitochondria-dependent apoptosis in CPF-treated cells.•Interaction of Drp1 with…”
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UPF1 Association with the Cap-Binding Protein, CBP80, Promotes Nonsense-Mediated mRNA Decay at Two Distinct Steps by Hwang, Jungwook, Sato, Hanae, Tang, Yalan, Matsuda, Daiki, Maquat, Lynne E.

“…Nonsense-mediated mRNA decay (NMD) is an mRNA surveillance mechanism that in mammals generally occurs upon recognition of a premature termination codon (PTC)…”
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