Search Results - "Hwang, Hyun S."

Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis by Boutaud, Olivier, Sosa, I Romina, Amin, Taneem, Oram, Denise, Adler, David, Hwang, Hyun S, Crews, Brenda C, Milne, Ginger, Harris, Bradford K, Hoeksema, Megan, Knollmann, Bjorn C, Lammers, Philip E, Marnett, Lawrence J, Massion, Pierre P, Oates, John A

“…Meta-analyses have demonstrated that low-dose aspirin reduces the risk of developing adenocarcinoma metastasis, and when colon cancer is detected during…”
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Compensatory calcium handling may underlie increased arrhythmia susceptibility of sarcospan-deficient mice after ischemia-reperfusion injury by Rahimi Kahmini, Aida, Valera, Isela C., Cejas Carbonell, Alexis, Prascak, Julia, Mumbi, Florence, Parvatiyar, Michelle S., Hwang, Hyun S.

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Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function by Landim-Vieira, Maicon, Ma, Weikang, Song, Taejeong, Rastegarpouyani, Hosna, Gong, Henry, Coscarella, Isabella Leite, Bogaards, Sylvia J P, Conijn, Stefan P, Ottenheijm, Coen A C, Hwang, Hyun S, Papadaki, Maria, Knollmann, Bjorn C, Sadayappan, Sakthivel, Irving, Thomas C, Galkin, Vitold E, Chase, P Bryant, Pinto, Jose Renato

“…Missense variant Ile79Asn in human cardiac troponin T (cTnT-I79N) has been associated with hypertrophic cardiomyopathy and sudden cardiac arrest in juveniles…”
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Dissecting the mechanisms by which a pathogenic variant in cardiac TnT tail domain leads to disturbed myofilament performance by Landim-Vieira, Maicon, Ma, Weikang, Song, Taejeong, Rastegarpouyani, Hosna, Ottenheijm, Coen A., Hwang, Hyun S., Gong, Henry M., Papadaki, Maria, Knollmann, Bjorn C., Sadayappan, Sakthivel, Irving, Thomas, Galkin, Vitold E., Chase, Prescott B., Pinto, J. Renato D.

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Focal Energy Deprivation Underlies Arrhythmia Susceptibility in Mice With Calcium-Sensitized Myofilaments by Huke, Sabine, Venkataraman, Raghav, Faggioni, Michela, Bennuri, Sirish, Hwang, Hyun S, Baudenbacher, Franz, Knollmann, Björn C

“…RATIONALE:The Ca sensitivity of the myofilaments is increased in hypertrophic cardiomyopathy and other heart diseases and may contribute to a higher risk for…”
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The moderating role of national economic development on the relationship between ESG and firm performance in the global hospitality industry by Hwang, Da Hyun S., Song, Hyoung Ju, Lee, Seoki, Kang, Kyung Ho

“…This study examines the effect of national economic development (NED) on the relationship between Environmental, Social, and Governance (ESG) and firm…”
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Strategic corporate social responsibility in the tourism and hospitality industry: Conceptual proposal by Lee, Seoki, Hwang, Da Hyun S, Shin, Minjung, Kang, Kyung Ho

“…Considering the growing significance of CSR in the corporate world, this study critically reflects the extant CSR literature and CSR practices, and proposes a…”
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Annulment of Cardiac Muscle Length-Dependent Force Activation in Transgenic Mice Bearing the HcTnT-I79N Mutation by Landim Vieira, Maicon, Knollmann, Bjorn, Hwang, Hyun S., Pinto, J. Renato, Chase, P. Bryant

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Osmotic Compression Influences Cross-Bridge Detachment Rate in Transgenic Hypertrophic Cardiomyopathy Variant Hctnt-I79N and Non-Transgenic Mouse Cardiac Muscle by Vieira, Maicon Landim, Knollmann, Bjorn C., Hwang, Hyun S., Ottenheijm, Coen A., Pinto, J. Renato D., Chase, Prescott B.

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The HCM I79N pathogenic variant in cardiac TNT induces thick filament malfunction and myofilament lattice rearrangement by Landim-Vieira, Maicon, Ma, Weikang, Song, Taejeong, Ottenheijm, Coen A., Hwang, Hyun S., Gong, Henry M., Papadaki, Maria, Knollmann, Bjorn C., Sadayappan, Sakthivel, Irving, Thomas C., Chase, Prescott B., Pinto, J. Renato

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Cardiac troponin T N-domain variant destabilizes the actin interface resulting in disturbed myofilament function by Landim-Vieira, Maicon, Ma, Weikang, Song, Taejeong, Rastegarpouyani, Hosna, Gong, Henry, Coscarella, Isabella Leite, Bogaards, Sylvia J. P., Conijn, Stefan P., Ottenheijm, Coen A. C., Hwang, Hyun S., Papadaki, Maria, Knollmann, Bjorn C., Sadayappan, Sakthivel, Irving, Thomas C., Galkin, Vitold E., Chase, P. Bryant, Pinto, Jose Renato

“…Missense variant Ile79Asn in human cardiac troponin T (cTnT-I79N) has been associated with hypertrophic cardiomyopathy and sudden cardiac arrest in juveniles…”
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Aberrant Cardiac Muscle Mechanics in a Hypertrophic Cardiomyopathy Troponin T ILE79ASN Transgenic Mouse by Dieseldorff Jones, Karissa M., Gonzalez-Martinez, David, Landim-Vieira, Maicon, Koh, Yeojung, Knollmann, Bjorn C., Chase, P. Bryant, Hwang, Hyun S., Pinto, Jose R.

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Abstract 17878: Calmodulin Mutation (CALM-F90L) Associated With Familial Idiopathic Ventricular Fibrillation Disrupts L-type Ca Channel Inactivation and Activates Sarcoplasmic Reticulum Ca Release in Ventricular Myocytes by Kryshtal, Dmytro, Hwang, Hyun S, Johnson, Christopher, Chazin, Walter, George, Alfred L, Knollmann, Bjorn

“…Abstract only Introduction: The F90L mutation in calmodulin (CaM) has been associated with a familial form of autosomal-dominant idiopathic ventricular…”
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Abnormal Cardiac Cross-Bridge Kinetics in a Troponin T ILE79ASN Transgenic Mouse Model by Gonzalez-Martinez, David, Jones, Karissa D., Landim-Vieira, Maicon, Lee, Kwangjun, Koh, Yeojung, Knollmann, Bjorn C., Chase, P. Bryant, Hwang, Hyun S., Pinto, Jose R.

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Divergent Regulation of Cardiomyocyte Cav1.2 Currents by Calmodulin Mutants Associated with Human Sudden Death Syndromes by Kryshtal, Dmytro O., Hwang, Hyun S., Johnson, Christopher N., Chazin, Walter J., George, Alfred L., Knollmann, Bjorn C.

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Abstract 66: Discovery of a Novel Pharmaceutical Class as Potential Heart Failure Treatment by Feaster, Tromondae K, Hempel, Jonathan E, Williams, Charles H, Frist, Audrey Y, Hwang, Hyun S, Knollmann, Bjorn C, Hong, Charles C

“…Abstract only Utilizing an unbiased in vivo phenotypic chemical screening platform in zebrafish embryos, our laboratory has identified a number of novel…”
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Abstract 351: Role of Ketoaldehyde Protein Adducts in Ischemic Cardiomyopathy by Hwang, Hyun S, Davies, Sean S, Hill, Michael F, Pessah, Isaac N, Allen, Paul D, Roberts, L. J, Knollmann, Bjorn C

“…Abstract only Background: Oxidative damage is an important component of ischemic heart injury. Isomeric ketoaldehydes, isoketals (IsoKs), are produced by the…”
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Abstract 19851: A Novel Inotropic Class With Unique Mechanism of Action Identified by a Phenotypic Screen by Hempel, Jonathan E, Williams, Charles H, Feaster, Tromondae K, Cadar, Adrian G, Hwang, Hyun S, Metzger, Joseph M, Knollmann, Bjorn K, Hong, Charles C

“…IntroductionHeart failure (HF) is a leading cause of disability and mortality in US, and there is tremendous unmet need for therapies targeting advanced…”
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Abstract 18898: Abnormal Conduction and Arrhythmias Precede the Development of Dilated Cardiomyopathy in D1275n Mutant Mice by Stroud, Dina M, Bersell, Kevin R, Delaney, Jessica, Hall, Lynn, Agullo-Pascual, Esperanza, Hwang, Hyun S, Yang, Tao, Knollmann, Bjorn, Delmar, Mario, Baudenbacher, Franz, Roden, Dan M

“…BackgroundThe D1275N SCN5A mutation is associated with dilated cardiomyopathy (DCM) in humans. We have previously reported that in 12 week old mice carrying…”
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Bioequivalence Study of a New Fixed-Dose Combination Tablet Containing S-Amlodipine Nicotinate and Olmesartan Medoxomil in Healthy Korean Male Subjects by Oh, Mi Jin, MS, Hwang, Hyun Hwan, MS, Kim, Hyun Gyu, PhD, Lee, Geun Hyeog, BS, Cho, Yun-Seok, PhD, Lee, Sun Young, BS, Kang, Soo Yeon, BS, Cho, Kyung Hee, MS, Lee, Yun Young, MS, Lee, Yun Jeong, PharmD, PhD, Jang, Choon-Gon, PhD, Lee, Seok-Yong, PhD

“…Abstract Purpose A fixed-dose combination (FDC) pill of amlodipine (relatively old calcium channel blocker as dihydropyridine) and olmesartan (relatively new…”
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