Search Results - "Hwa, Yi Lisa"
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Risk stratification of smoldering multiple myeloma incorporating revised IMWG diagnostic criteria
Published in Blood cancer journal (New York) (12-06-2018)“…In 2014, the International Myeloma Working Group reclassified patients with smoldering multiple myeloma (SMM) and bone marrow-plasma cell percentage (BMPC%) ≥…”
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2
Bone marrow plasma cells 20% or greater discriminate presentation, response, and survival in AL amyloidosis
Published in Leukemia (01-04-2020)“…We explored the association between bone marrow plasma cells (BMPCs) and disease presentation and outcome among 1574 AL patients. Three BMPC groups were…”
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3
Characterization and prognostic implication of delayed complete response in AL amyloidosis
Published in European journal of haematology (01-03-2021)“…Introduction Little is known on continued response following completion of therapy in light chain (AL) amyloidosis. Methods We studied 373 AL amyloidosis…”
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4
Transition of LINE-1 DNA methylation status and altered expression in first and third trimester placentas
Published in PloS one (12-05-2014)“…DNA methylation plays a critical role in the regulation of gene expression, genomic DNA stability, cell proliferation, and malignant transformation. Common…”
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5
Improved outcomes for newly diagnosed AL amyloidosis between 2000 and 2014: cracking the glass ceiling of early death
Published in Blood (13-04-2017)“…In light of major advances in immunoglobulin light chain (AL) amyloidosis, we evaluated the trends in presentation, management, and outcome among 1551 newly…”
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6
Depth of organ response in AL amyloidosis is associated with improved survival: grading the organ response criteria
Published in Leukemia (01-10-2018)“…Organ recovery following anti-plasma cell therapy is associated with improved outcome in patients with AL amyloidosis. Current organ response criteria do not…”
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7
Ten‐year survivors in AL amyloidosis: characteristics and treatment pattern
Published in British journal of haematology (01-12-2019)“…Summary Improvement in survival in Light chain (AL) amyloidosis has been seen over recent decades, enabling more patients to achieve long‐term survival…”
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8
Optimizing deep response assessment for AL amyloidosis using involved free light chain level at end of therapy: failure of the serum free light chain ratio
Published in Leukemia (01-02-2019)Get full text
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9
Enhancing the R‐ISS classification of newly diagnosed multiple myeloma by quantifying circulating clonal plasma cells
Published in American journal of hematology (01-03-2020)“…Our prior studies identified the prognostic significance of quantifying cPCs by multiparametric flow cytometry (MFC) in newly diagnosed multiple myeloma (NDMM)…”
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10
Sarcopenia identified by computed tomography imaging using a deep learning–based segmentation approach impacts survival in patients with newly diagnosed multiple myeloma
Published in Cancer (01-02-2023)“…Background Sarcopenia increases with age and is associated with poor survival outcomes in patients with cancer. By using a deep learning–based segmentation…”
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11
Outcomes with different administration schedules of bortezomib in bortezomib, lenalidomide and dexamethasone (VRd) as first‐line therapy in multiple myeloma
Published in American journal of hematology (01-03-2021)“…Induction therapy for multiple myeloma with bortezomib (Velcade), lenalidomide (Revlimid), and dexamethasone (d) (VRd) was traditionally administered as…”
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12
Relapse after complete response in newly diagnosed multiple myeloma: implications of duration of response and patterns of relapse
Published in Leukemia (01-03-2019)“…Achieving a complete response (CR) is associated with improved overall survival (OS) in multiple myeloma (MM), but data on duration of CR (DurCR) are limited…”
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13
Refining amyloid complete hematological response: Quantitative serum free light chains superior to ratio
Published in American journal of hematology (01-11-2020)“…Response assessment in light chain (AL) amyloidosis is based on serum and urine monoclonal protein studies. Newly diagnosed patients (n = 373) who achieved…”
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14
Utilizing multiparametric flow cytometry in the diagnosis of patients with primary plasma cell leukemia
Published in American journal of hematology (01-06-2020)“…The diagnosis of primary plasma cell leukemia (pPCL) has been made by quantifying circulating plasma cells (cPCs) morphologically on a peripheral blood (PB)…”
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15
Prognostic significance of acquired 1q22 gain in multiple myeloma
Published in American journal of hematology (01-01-2022)“…Gain of 1q22 at diagnosis portends poorer outcomes in multiple myeloma (MM), but the prognostic significance of acquired 1q22 gain is unknown. We identified 63…”
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16
Prognostic significance of interphase FISH in monoclonal gammopathy of undetermined significance
Published in Leukemia (01-08-2018)Get full text
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17
Hypovitaminosis D Is Prevalent in Patients With Renal AL Amyloidosis and Associated With Renal Outcome
Published in Frontiers in endocrinology (Lausanne) (21-06-2022)“…Vitamin D deficiency is common, but no data have been reported on vitamin D levels in light chain (AL) amyloidosis. In this exploratory study, stored serum…”
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18
Impact of prior melphalan exposure on stem cell collection in light chain amyloidosis
Published in Bone marrow transplantation (Basingstoke) (01-03-2018)“…Use of melphalan in multiple myeloma was observed to have a deleterious effect on stem cell collection in older studies. There is limited data on the impact of…”
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Phase 1/2 trial of ixazomib, cyclophosphamide and dexamethasone in patients with previously untreated symptomatic multiple myeloma
Published in Blood cancer journal (New York) (30-07-2018)“…Ixazomib is the first oral proteasome inhibitor to enter the clinic. Given the efficacy of bortezomib in combination with cyclophosphamide and dexamethasone,…”
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20
Utility and prognostic value of 18F‐FDG positron emission tomography‐computed tomography scans in patients with newly diagnosed multiple myeloma
Published in American journal of hematology (01-12-2018)“…Positron emission tomography‐computed tomography (PET‐CT) can identify bony lesions, assess disease burden, and detect extramedullary disease (EMD) in patients…”
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