Search Results - "Hwa, J"

New Routes to Targeted Therapy of Intrahepatic Cholangiocarcinomas Revealed by Next‐Generation Sequencing by Ross, Jeffrey S., Wang, Kai, Gay, Laurie, Al‐Rohil, Rami, Rand, Janne V., Jones, David M., Lee, Hwa J., Sheehan, Christine E., Otto, Geoff A., Palmer, Gary, Yelensky, Roman, Lipson, Doron, Morosini, Deborah, Hawryluk, Matthew, Catenacci, Daniel V. T., Miller, Vincent A., Churi, Chaitanya, Ali, Siraj, Stephens, Philip J.

“…Background. Intrahepatic cholangiocarcinoma (ICC) is a subtype of primary liver cancer that is rarely curable by surgery and is rapidly increasing in…”
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Gene Expression Profiling Reveals Renin mRNA Overexpression in Human Hypertensive Kidneys and a Role for MicroRNAs by Marques, Francine Z, Campain, Anna E, Tomaszewski, Maciej, Zukowska-Szczechowska, Ewa, Yang, Yee Hwa J, Charchar, Fadi J, Morris, Brian J

“…The kidney has long been invoked in the etiology of essential hypertension. This could involve alterations in expression of specific genes and microRNAs…”
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Prostacyclin, Atherothrombosis and Diabetes Mellitus: Physiologic and Clinical Considerations by Stitham, J, Hwa, J

“…Prostacyclin (PGI2) and other metabolites of arachidonic acid are increasingly recognized for their role in the pathophysiology of human disease. A growing…”
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Transplantation of Macroencapsulated Insulin-Producing Cells by Hwa, Albert J., Weir, Gordon C.

“…Purpose of Review There is considerable interest in using macroencapsulation devices as a delivery strategy for transplanting insulin-producing cells. This…”
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Enhancement of Subcutaneous Islet Transplant Performance by Collagen 1 Gel by French, Anna, Hollister-Lock, Jennifer, Sullivan, Brooke A, Stas, Eline, Hwa, Albert J, Weir, Gordon C, Bonner-Weir, Susan

“…Human islets can be transplanted into the portal vein for T1 diabetes, and a similar procedure is being used in a clinical trial for stem cell-derived…”
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Spontaneous Cerebrospinal fluid effusion of the temporal bone: Repair, audiological outcomes, and obesity by Son, Hwa J., Karkas, Alexandre, Buchanan, Patrick, Giurintano, Jonathan P., Theodosopoulos, Philip, Pensak, Myles L., Samy, Ravi N.

“…Objectives/Hypothesis Spontaneous occurrence of otogenic cerebrospinal fluid (CSF) effusion is now far more prevalent than causes related to infections, prior…”
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Transcriptome-wide targets of alternative splicing by RBM4 and possible role in cancer by Markus, M. Andrea, Yang, Yee Hwa J., Morris, Brian J.

“…This study determined transcriptome-wide targets of the splicing factor RBM4 using Affymetrix GeneChip® Human Exon 1.0 ST Arrays and HeLa cells treated with…”
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The Chinese and Korean American immigrant experience: a mixed-methods examination of facilitators and barriers of colorectal cancer screening by Jung, Mary Y., Holt, Cheryl L., Ng, Diane, Sim, Hwa J., Lu, Xiaoxiao, Le, Daisy, Juon, Hee-Soon, Li, Jun, Lee, Sunmin

“…Objective: Among Asian Americans, colorectal cancer (CRC) is the second leading cause of cancer deaths. Despite strong evidence that screening can reduce…”
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Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress by Ameri, Kurosh, Rajah, Anthony M, Nguyen, Vien, Sanders, Timothy A, Jahangiri, Arman, Delay, Michael, Donne, Matthew, Choi, Hwa J, Tormos, Kathryn V, Yeghiazarians, Yerem, Jeffrey, Stefanie S, Rinaudo, Paolo F, Rowitch, David H, Aghi, Manish, Maltepe, Emin

“…Cellular stress responses are frequently governed by the subcellular localization of critical effector proteins. Apoptosis-inducing Factor (AIF) or…”
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ECM-dependent HIF induction directs trophoblast stem cell fate via LIMK1-mediated cytoskeletal rearrangement by Choi, Hwa J, Sanders, Timothy A, Tormos, Kathryn V, Ameri, Kurosh, Tsai, Justin D, Park, Angela M, Gonzalez, Julissa, Rajah, Anthony M, Liu, Xiaowei, Quinonez, Diana M, Rinaudo, Paolo F, Maltepe, Emin

“…The Hypoxia-inducible Factor (HIF) family of transcriptional regulators coordinates the expression of dozens of genes in response to oxygen deprivation…”
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ZRANB2 localizes to supraspliceosomes and influences the alternative splicing of multiple genes in the transcriptome by Yang, Yee Hwa J., Markus, M. Andrea, Mangs, A. Helena, Raitskin, Oleg, Sperling, Ruth, Morris, Brian J.

“…Alternative splicing is a major source of protein diversity in humans. The human splicing factor zinc finger, Ran-binding domain containing protein 2 (ZRANB2)…”
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Meta-Analysis of Genome-Wide Gene Expression Differences in Onset and Maintenance Phases of Genetic Hypertension by Marques, Francine Z, Campain, Anna E, Yang, Yee Hwa J, Morris, Brian J

“…Gene expression differences accompany both the onset and established phases of hypertension. By an integrated genome-transcriptome approach we performed a…”
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Optimal management of single-sided deafness by Son, Hwa J., Choo, Daniel

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Differential expression of circulating microRNAs according to severity of colorectal neoplasia by Ho, Gloria Y.F, Jung, Hwa J, Schoen, Robert E, Wang, Tao, Lin, Juan, Williams, Zev, Weissfeld, Joel L, Park, Jung Y, Loudig, Olivier, Suh, Yousin

“…There is a need to develop a colorectal cancer (CRC) screening test that is noninvasive, cost effective, and sensitive enough to detect preneoplastic lesions…”
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Cardiovascular pharmacogenetics of antihypertensive and lipid- lowering therapies by Vanichakarn, P, Hwa, J, Stitham, J

“…Recent changes to the clinical management guidelines for hypertension and hyperlipidemia have placed emphasis on prevention through the pharmacological control…”
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Decreased bone marrow activity measured by using 18F-fluorodeoxyglucose positron emission tomography among patients with cerebral artery atherosclerosis by Kim, J.M, Eun Seoung, L, Kwang-Yeol, P, Ju Won, S, Keun-Hwa, J

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Prostacyclin receptor regulation--from transcription to trafficking by Midgett, C, Stitham, J, Martin, K A, Hwa, J

“…The prostacyclin receptor (IP--International Union of Pharmacology nomenclature) is a member of the seven transmembrane G-protein coupled receptor (GPCR)…”
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Cardiovascular pharmacogenetics of anti-thrombotic agents and non-steroidal anti-inflammatory drugs by Stitham, J, Vanichakarn, P, Ying, L, Hwa, J

“…The use of antithrombotic agents, particularly antiplatelet drugs like aspirin and clopidogrel, has been instrumental in decreasing the risk for adverse…”
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Genes influencing circadian differences in blood pressure in hypertensive mice by Marques, Francine Z, Campain, Anna E, Davern, Pamela J, Yang, Yee Hwa J, Head, Geoffrey A, Morris, Brian J

“…Essential hypertension is a common multifactorial heritable condition in which increased sympathetic outflow from the central nervous system is involved in the…”
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Fat Intake Affects Adiposity, Comorbidity Factors, and Energy Metabolism of Sprague-Dawley Rats by Ghibaudi, Lorraine, Cook, John, Farley, Constance, Heek, Margaret, Hwa, Joyce J.

“…Objective: Childhood obesity is an emerging health problem. This study assesses the effects of three levels of dietary fat (10%, 32%, and 45% measured by…”
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