Search Results - "Hutz, M H"

Meta-analysis and systematic review of ADGRL3 (LPHN3) polymorphisms in ADHD susceptibility by Bruxel, E. M., Moreira-Maia, C. R., Akutagava-Martins, G. C., Quinn, T. P., Klein, M., Franke, B., Ribasés, M., Rovira, P., Sánchez-Mora, C., Kappel, D. B., Mota, N. R., Grevet, E. H., Bau, C. H. D., Arcos-Burgos, M., Rohde, L. A., Hutz, M. H.

“…The gene encoding adhesion G protein-coupled receptor L3 ( ADGRL3 , also referred to as latrophilin 3 or LPHN3 ) has been associated with ADHD susceptibility…”
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LPHN3 and attention‐deficit/hyperactivity disorder: a susceptibility and pharmacogenetic study by Bruxel, E. M., Salatino‐Oliveira, A., Akutagava‐Martins, G. C., Tovo‐Rodrigues, L., Genro, J. P., Zeni, C. P., Polanczyk, G. V., Chazan, R., Schmitz, M., Arcos‐Burgos, M., Rohde, L. A., Hutz, M. H.

“…Latrophilin 3 (LPHN3) is a brain‐specific member of the G‐protein coupled receptor family associated to both attention‐deficit/hyperactivity disorder (ADHD)…”
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N-acetyl transferase 2 and cytochrome P450 2E1 genes and isoniazid-induced hepatotoxicity in Brazilian patients by Santos, N. P. C., Callegari-Jacques, S. M., Ribeiro dos Santos, A. K. C., Silva, C. A., Vallinoto, A. C. R., Fernandes, D. C. R. O., de Carvalho, D. C., Santos, S. E. B., Hutz, M. H.

“…SETTING: Isoniazid (INH) is related to the development of hepatotoxicity in some patients.OBJECTIVE: To investigate the role of N-acetyl transferase 2 (NAT2)…”
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Association between DRD2 and DRD3 gene polymorphisms and gastrointestinal symptoms induced by levodopa therapy in Parkinson’s disease by Rieck, M, Schumacher-Schuh, A F, Altmann, V, Callegari-Jacques, S M, Rieder, C R M, Hutz, M H

“…Levodopa is the most used drug to treat motor symptoms in Parkinson’s disease (PD). However, dopaminergic side effects such as nausea and vomiting may occur…”
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Association of slow N-acetyltransferase 2 profile and anti-TB drug-induced hepatotoxicity in patients from Southern Brazil by Possuelo, L. G., Castelan, J. A., de Brito, T. C., Ribeiro, A. W., Cafrune, P. I., Picon, P. D., Santos, A. R., Teixeira, R. L. F., Gregianini, T. S., Hutz, M. H., Rossetti, M. L. R., Zaha, A.

“…Purpose To determine the frequency of N-acetyltransferase 2 ( NAT2 ) polymorphisms, the NAT2 acetylation profile and its relation to the incidence of…”
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Cytokine gene polymorphisms are associated with susceptibility to tuberculosis in an Amerindian population by Lindenau, J. D., Guimarães, L. S. P., Friedrich, D. C., Hurtado, A. M., Hill, K. R., Salzano, F. M., Hutz, M. H.

“…SETTING: Cytokines play an important role in anti-tuberculosis immune response, combined with antigen-presenting cells and lymphocytes. Immune response gene…”
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Is there a role for rare variants in DRD4 gene in the susceptibility for ADHD? Searching for an effect of allelic heterogeneity by Tovo-Rodrigues, L, Rohde, L A, Roman, T, Schmitz, M, Polanczyk, G, Zeni, C, Marques, F Z C, Contini, V, Grevet, E H, Belmonte-de-Abreu, P, Bau, C H D, Hutz, M H

“…Although several studies have demonstrated an association between the 7-repeat (7R) allele in the 48-bp variable number of tandem repeats (VNTRs) in the exon 3…”
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DRD2/DRD4 heteromerization may influence genetic susceptibility to alcohol dependence by Mota, N R, Rovaris, D L, Bertuzzi, G P, Contini, V, Vitola, E S, Grevet, E H, Roman, T, Callegari-Jacques, S M, Hutz, M H, Bau, C H D

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Association study of GIT1 gene with attention‐deficit hyperactivity disorder in Brazilian children and adolescents by Salatino‐Oliveira, A., Genro, J. P., Chazan, R., Zeni, C., Schmitz, M., Polanczyk, G., Roman, T., Rohde, L. A., Hutz, M. H.

“…This paper reports that the association of the GIT1 gene with attention‐deficit hyperactivity disorder previously reported was not observed in Brazilian…”
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Association analysis of genes involved in the leptin-signaling pathway with obesity in Brazil by MATTEVI, V. S, ZEMBRZUSKI, V. M, HUTZ, M. H

“…To investigate associations of polymorphisms in the LEP, LEPR and NPY genes with obesity-related traits in a Brazilian population of European descent. A total…”
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Polymorphisms in the DBH and DRD2 gene regions and smoking behavior by Freire, Maria Teresa M V, Marques, Francine Z C, Hutz, Mara H, Bau, Claiton H D

“…The DRD2 TaqI A and DBH-1021 C/T polymorphisms were genotyped in smoking alcoholics (N = 100), non-alcoholic smokers (N = 120) and nonsmoking controls (N =…”
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Further evidence of the involvement of alpha-2A-adrenergic receptor gene (ADRA2A) in inattentive dimensional scores of attention-deficit hyperactivity disorder by Roman, T, Polanczyk, G V, Zeni, C, Genro, J P, Rohde, L A, Hutz, M H

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Functional characterization of G-protein-coupled receptors: A bioinformatics approach by Tovo-Rodrigues, L, Roux, A, Hutz, M.H, Rohde, L.A, Woods, A.S

“…Graphical abstract…”
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High frequency of the CCR5delta32 variant among individuals from an admixed Brazilian population with sickle cell anemia by Chies, J A B, Hutz, M H

“…Homozygous sickle cell disease (SCD) has a wide spectrum of clinical manifestations. In Brazil, the main cause of death of individuals with SCD is recurrent…”
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Investigation of genetic susceptibility to Mycobacterium tuberculosis (VDR and IL10 genes) in a population with a high level of substructure in the Brazilian Amazon region by Silva, C.A., Fernandes, D.C.R.O., Braga, A.C.O., Cavalcante, G.C., Sortica, V.A., Hutz, M.H., Leal, D.F.V.B., Fernades, M.R., Santana-da-Silva, M.N., Lopes Valente, S.E., Pastana, L.F., Pinto, P.D.C., Costa, G.E., Ribeiro-dos-Santos, A., Santos, S., Santos, N.P.C.

“…•The host genetics has been related to susceptibility to Mycobacterium tuberculosis infection.•Gene polymorphisms in VDR, IL10, and SLC11A1 have been…”
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Association of a carboxylesterase 1 polymorphism with appetite reduction in children and adolescents with attention-deficit/hyperactivity disorder treated with methylphenidate by Bruxel, E M, Salatino-Oliveira, A, Genro, J P, Zeni, C P, Polanczyk, G V, Chazan, R, Rohde, L A, Hutz, M H

“…Carboxylesterase 1 is the enzyme involved in methylphenidate (MPH) metabolism. The aim of this study was to evaluate the association between a −75 T>G…”
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ESR1 polymorphisms and statin therapy: a sex-specific approach by Smiderle, L, Fiegenbaum, M, Hutz, M H, Van Der Sand, C R, Van Der Sand, L C, Ferreira, M E W, Pires, R C, Almeida, S

“…Lipid-lowering therapy has shown a high degree of variability in clinical response and there is evidence that the variability in drug response between…”
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Association of common genetic variants of HOMER1 gene with levodopa adverse effects in Parkinson’s disease patients by Schumacher-Schuh, A F, Altmann, V, Rieck, M, Tovo-Rodrigues, L, Monte, T L, Callegari-Jacques, S M, Medeiros, M S, Rieder, C R M, Hutz, M H

“…Levodopa is the most effective symptomatic therapy for Parkinson’s disease, but its chronic use could lead to chronic adverse outcomes, such as motor…”
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The DBH -1021 C/T polymorphism is not associated with alcoholism but possibly with patients' exposure to life events by Freire, M T M V, Hutz, M H, Bau, C H D

“…Two DBH polymorphisms were investigated in 114 Brazilian alcoholics of European descent and 233 controls. Personality and life events were also analyzed among…”
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DRD4 and DAT1 as modifying genes in alcoholism: interaction with novelty seeking on level of alcohol consumption by Bau, C H, Almeida, S, Costa, F T, Garcia, C E, Elias, E P, Ponso, A C, Spode, A, Hutz, M H

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