Search Results - "Huttu, Kristiina"

Compensatory Enhancement of Intrinsic Spiking upon NKCC1 Disruption in Neonatal Hippocampus by Sipila, Sampsa T, Huttu, Kristiina, Yamada, Junko, Afzalov, Ramil, Voipio, Juha, Blaesse, Peter, Kaila, Kai

“…Depolarizing and excitatory GABA actions are thought to be important in cortical development. We show here that GABA has no excitatory action on CA3 pyramidal…”
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Depolarizing GABA Acts on Intrinsically Bursting Pyramidal Neurons to Drive Giant Depolarizing Potentials in the Immature Hippocampus by Sipila, Sampsa T, Huttu, Kristiina, Soltesz, Ivan, Voipio, Juha, Kaila, Kai

“…Spontaneous periodic network events are a characteristic feature of developing neuronal networks, and they are thought to play a crucial role in the maturation…”
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Distinct properties of functional KCC2 expression in immature mouse hippocampal neurons in culture and in acute slices by Khirug, Stanislav, Huttu, Kristiina, Ludwig, Anastasia, Smirnov, Sergei, Voipio, Juha, Rivera, Claudio, Kaila, Kai, Khiroug, Leonard

“…A hallmark in the development of GABAergic neurotransmission is the switch in GABAA‐mediated responses from depolarizing to hyperpolarizing. This occurs due to…”
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Carbonic Anhydrase Isoform VII Acts as a Molecular Switch in the Development of Synchronous Gamma-Frequency Firing of Hippocampal CA1 Pyramidal Cells by Ruusuvuori, Eva, Li, Hong, Huttu, Kristiina, Palva, J. Matias, Smirnov, Sergei, Rivera, Claudio, Kaila, Kai, Voipio, Juha

“…Identification of the molecular mechanisms that enable synchronous firing of CA1 pyramidal neurons is central to the understanding of the functional properties…”
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Intrinsic bursting of immature CA3 pyramidal neurons and consequent giant depolarizing potentials are driven by a persistent Na+ current and terminated by a slow Ca2+-activated K+ current by Sipilä, Sampsa T., Huttu, Kristiina, Voipio, Juha, Kaila, Kai

“…The CA3 area of the mature hippocampus is known for its ability to generate intermittent network activity both in physiological and in pathological conditions…”
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GABA Uptake via GABA Transporter-1 Modulates GABAergic Transmission in the Immature Hippocampus by Sipila, Sampsa, Huttu, Kristiina, Voipio, Juha, Kaila, Kai

“…GABA uptake limits GABA actions during synaptic responses when the density of active release sites is high or multiple axons are synchronously activated. GABA…”
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Intrinsic bursting of immature CA3 pyramidal neurons and consequent giant depolarizing potentials are driven by a persistent Na + current and terminated by a slow Ca 2+ ‐activated K + current by Sipilä, Sampsa T., Huttu, Kristiina, Voipio, Juha, Kaila, Kai

“…Abstract The CA3 area of the mature hippocampus is known for its ability to generate intermittent network activity both in physiological and in pathological…”
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Intrinsic bursting of immature CA3 pyramidal neurons and consequent giant depolarizing potentials are driven by a persistent Na super(+) current and terminated by a slow Ca super(2+)-activated K super(+) current by Sipilae, Sampsa T, Huttu, Kristiina, Voipio, Juha, Kaila, Kai

“…The CA3 area of the mature hippocampus is known for its ability to generate intermittent network activity both in physiological and in pathological conditions…”
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