Search Results - "Hutson, S M"

Chronic activation of mTOR complex 1 by branched chain amino acids and organ hypertrophy by Neishabouri, S. Hallaj, Hutson, S. M, Davoodi, J

“…The mitochondrial branched chain aminotransferase-deficient mouse model (BCATm KO), which exhibits elevated plasma and tissue branched chain amino acids…”
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Energy sources for glutamate neurotransmission in the retina: absence of the aspartate/glutamate carrier produces reliance on glycolysis in glia by Xu, Y., Ola, M. S., Berkich, D. A., Gardner, T. W., Barber, A. J., Palmieri, F., Hutson, S. M., LaNoue, K. F.

“…The mitochondrial transporter, the aspartate/glutamate carrier (AGC), is a necessary component of the malate/aspartate cycle, which promotes the transfer into…”
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Role of Branched‐Chain Aminotransferase Isoenzymes and Gabapentin in Neurotransmitter Metabolism by Hutson, S. M., Berkich, D., Drown, P., Xu, Baiyang, Aschner, Michael, LaNoue, Kathryn F.

“…: Because it is well known that excess branched‐chain amino acids (BCAAs) have a profound influence on neurological function, studies were conducted to…”
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Matrix Gla protein (MGP) and bone morphogenetic protein‐2 in aortic calcified lesions of aging rats by Sweatt, A., Sane, D. C., Hutson, S. M., Wallin, R.

“…The vitamin K‐dependent protein, matrix Gla protein (MGP) is a binding protein for bone morphogenetic protein‐2 (BMP‐2). Here we present additional evidence…”
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6450 nm wavelength tissue ablation using a nanosecond laser based on difference frequency mixing and stimulated Raman scattering by Edwards, G S, Pearlstein, R D, Copeland, M L, Hutson, M S, Latone, K, Spiro, A, Pasmanik, G

“…A four-stage laser system was developed, emitting at a wavelength of 6450 nm with a 3-5 ns pulse duration, < or = 2 mJ pulse energy, and 1/2 Hz pulse…”
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A molecular model of human branched-chain amino acid metabolism by SURYAWAN, A, HAWES, J. W, HARRIS, R. A, SHIMOMURA, Y, JENKINS, A. E, HUTSON, S. M

“…To establish an accurate molecular model of human branched-chain amino acid (BCAA) metabolism, the distribution, activity, and expression of the first 2…”
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Modulation of the binding of matrix Gla protein (MGP) to bone morphogenetic protein-2 (BMP-2) by Wallin, R, Cain, D, Hutson, S M, Sane, D C, Loeser, R

“…Matrix Gla protein (MGP) is an inhibitor of calcification of the arterial wall but the mechanism of inhibition has not been resolved. Since chondrogenesis has…”
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A molecular mechanism for genetic warfarin resistance in the rat by Wallin, Reidar, Hutson, Susan M., Cain, Dean, Sweatt, Andrew, Sane, David C.

“…ABSTRACT Warfarin targets vitamin K 2,3‐epoxide reductase (VKOR), the enzyme that produces reduced vitamin K, a required cofactor for γ‐carboxylation of…”
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Branched chain aminotransferase isoenzymes. Purification and characterization of the rat brain isoenzyme by HALL, T. R, WALLIN, R, REINHART, G. D, HUTSON, S. M

“…This paper presents the first complete purification of the branched chain aminotransferase (EC 2.6.1.42) from rat brain cytosol (BCATc). On sodium dodecyl…”
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Mitochondrial transport proteins of the brain by Berkich, D.A., Ola, M.S., Cole, J., Sweatt, A.J., Hutson, S.M., LaNoue, K.F.

“…In this study, cellular distribution and activity of glutamate and γ‐aminobutyric acid (GABA) transport as well as oxoglutarate transport across brain…”
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Upregulation of Forces and Morphogenic Asymmetries in Dorsal Closure during Drosophila Development by Peralta, X.G., Toyama, Y., Hutson, M.S., Montague, R., Venakides, S., Kiehart, D.P., Edwards, G.S.

“…Tissue dynamics during dorsal closure, a stage of Drosophila development, provide a model system for cell sheet morphogenesis and wound healing. Dorsal closure…”
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Identification of mitochondrial branched chain aminotransferase and its isoforms in rat tissues by HUTSON, S. M, WALLIN, R, HALL, T. R

“…The tissue distribution and subcellular location of branched chain aminotransferase was analyzed using polyclonal antibodies against the enzyme purified from…”
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Warfarin resistance is associated with a protein component of the vitamin K 2,3-epoxide reductase enzyme complex in rat liver by Cain, D, Hutson, S M, Wallin, R

“…Warfarin, the most used drug in the world in long-term anticoagulation prophylaxis, targets the vitamin K 2,3-epoxide reductase (VKOR) of the vitamin K cycle…”
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Evidence for a Perturbation of Arginine-82 in the Bacteriorhodopsin Photocycle from Time-Resolved Infrared Spectra by Hutson, M. Shane, Alexiev, Ulrike, Shilov, Sergey V, Wise, Kevin J, Braiman, Mark S

“…Arginine-82 (R82) of bacteriorhodopsin (bR) has long been recognized as an important residue due to its absolute conservation in the archaeal rhodopsins and…”
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The valine catabolic pathway in human liver: Effect of cirrhosis on enzyme activities by Taniguchi, K, Nonami, T, Nakao, A, Harada, A, Kurokawa, T, Sugiyama, S, Fujitsuka, N, Shimomura, Y, Hutson, S M, Harris, R A, Takagi, H

“…The activities of key enzymes in the valine catabolic pathway–branched‐chain aminotransferase, branched‐chain alpha‐keto acid dehydrogenase complex,…”
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Regulation of branched-chain amino acid metabolism in the lactating rat by DeSantiago, S, Torres, N, Suryawan, A, Tovar, A R, Hutson, S M

“…There is evidence that during lactation, uptake of the essential branched-chain amino acids (BCAA) by mammary glands exceeds their output in milk protein. In…”
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Role of mitochondrial transamination in branched chain amino acid metabolism by Hutson, S M, Fenstermacher, D, Mahar, C

“…Oxidative decarboxylation and transamination of 1-14C-branched chain amino and alpha-keto acids were examined in mitochondria isolated from rat heart…”
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Warfarin and the Vitamin K-Dependent γ-Carboxylation System by Wallin, Reidar, Hutson, Susan M

“…Insight into the molecular basis for genetic warfarin resistance has recently been accomplished by the identification of an 18-kDa protein of the endoplasmic…”
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The inhibitory effect of calumenin on the vitamin K-dependent gamma-carboxylation system. Characterization of the system in normal and warfarin-resistant rats by Wajih, Nadeem, Sane, David C, Hutson, Susan M, Wallin, Reidar

“…The vitamin K-dependent gamma-carboxylation system is responsible for post-translational modification of vitamin K-dependent proteins, converting them to…”
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Pulmonary hypertension predicts mortality in infants with omphalocele by Baerg, J E, Thorpe, D L, Sharp, N E, Ramlogan, S R, Hutson, S M, Goff, D A, Hopper, A O, St Peter, S D

“…The objective of this study was to identify predictors of mortality in infants with omphalocele. Medical records of infants with omphalocele born between…”
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