Search Results - "Huth, Sebastian"

Comprehensive molecular characterization of microneedling therapy in a human three-dimensional skin model by Schmitt, Laurenz, Marquardt, Yvonne, Amann, Philipp, Heise, Ruth, Huth, Laura, Wagner-Schiffler, Sylvia, Huth, Sebastian, Baron, Jens-Malte

“…Microneedling therapy is a widely used technique in dermatology. However, little is known about the underlying molecular effects of this therapy on…”
Get full text

Conductance artery stiffness impairs atrio-ventriculo-arterial coupling before manifestation of arterial hypertension or left ventricular hypertrophic remodelling by Kyhl, Kasper, von Huth, Sebastian, Bojer, Annemie, Thomsen, Carsten, Engstrøm, Thomas, Vejlstrup, Niels, Madsen, Per Lav

“…As part of normal ageing, conductance arteries lose their cushion function, left ventricle (LV) filling and also left atrial emptying are impaired. The…”
Get full text

Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer by Huth, Sebastian, Huth, Laura, Heise, Ruth, Marquardt, Yvonne, Lopopolo, Linda, Piecychna, Marta, Boor, Peter, Fingerle-Rowson, Günter, Kapurniotu, Aphrodite, Yazdi, Amir S., Bucala, Richard, Bernhagen, Jürgen, Baron, Jens Malte

“…Non-melanoma skin cancer (NMSC) is the most common cancer in Caucasians worldwide. We investigated the pathophysiological role of MIF and its homolog D-DT in…”
Get full text

Effects of a ceramide‐containing water‐in‐oil ointment on skin barrier function and allergen penetration in an IL‐31 treated 3D model of the disrupted skin barrier by Huth, Sebastian, Schmitt, Laurenz, Marquardt, Yvonne, Heise, Ruth, Lüscher, Bernhard, Amann, Philipp M., Baron, Jens M.

“…Atopic dermatitis (AD) is a chronically relapsing, pruritic inflammation of the skin with dryness and disturbed skin barrier function. Recently, we established…”
Get full text

No effect of deleted in malignant brain tumors 1 deficiency on chemotherapy induced murine intestinal mucositis by Nexoe, Anders B., Pedersen, Andreas A., von Huth, Sebastian, Sorensen, Grith L., Holmskov, Uffe, Jiang, Ping-Ping, Detlefsen, Sönke, Husby, Steffen, Rathe, Mathias

“…Mucositis is a serious adverse effect of chemotherapeutic treatment. During intestinal mucositis, the mucosal barrier is compromised, increasing the risk of…”
Get full text

Effect of sildenafil on skeletal and cardiac muscle in Becker muscular dystrophy by Witting, Nanna, Kruuse, Christina, Nyhuus, Bo, Prahm, Kira P., Citirak, Gulsenay, Lundgaard, Stine J., von Huth, Sebastian, Vejlstrup, Niels, Lindberg, Ulrich, Krag, Thomas O., Vissing, John

“…Objective Patients with Becker muscular dystrophy (BMD) and Duchenne muscular dystrophy lack neuronal nitric oxide synthase (nNOS). nNOS mediates physiological…”
Get full text

Atypical presentation of Lemierre's syndrome caused by penicillin-susceptible Staphylococcus aureus in a patient with chronic stomatitis and COVID-19 by Burgdorf, Emma, Jensen, Janni, Grimm, Peter, von Huth, Sebastian

“…A healthy man in his late 20s was admitted to the emergency department due to a flare-up in his severe chronic stomatitis, along with flu-like symptoms. CXR…”
Get more information

Establishment of an Intradermal Ear Injection Model of IL-17A and IL-36γ as a Tool to Investigate the Psoriatic Cytokine Network by Kluwig, David, Huth, Sebastian, Abdallah, Ali T., Pfaff, Carolina M., Fietkau, Katharina, Huth, Laura, Marquardt, Yvonne, Baron, Jens M., Lüscher, Bernhard

“…Psoriasis is a chronic skin disease affecting 2–3% of the global population. The proinflammatory IL-17A is a key cytokine in psoriasis. Accumulating evidence…”
Get full text

Minor compositional alterations in faecal microbiota after five weeks and five months storage at room temperature on filter papers by von Huth, Sebastian, Thingholm, Louise Bruun, Bang, Corinna, Rühlemann, Malte C., Franke, Andre, Holmskov, Uffe

“…The gut microbiota is recognized as having major impact in health and disease. Sample storage is an important aspect to obtain reliable results. Mostly…”
Get full text

Intestinal protozoan infections shape fecal bacterial microbiota in children from Guinea-Bissau by von Huth, Sebastian, Thingholm, Louise B, Kofoed, Poul-Erik, Bang, Corinna, Rühlemann, Malte C, Franke, Andre, Holmskov, Uffe

“…Intestinal parasitic infections, caused by helminths and protozoa, are globally distributed and major causes of worldwide morbidity. The gut microbiota may…”
Get full text

SARS-CoV-2 seroprevalence among 7950 healthcare workers in the Region of Southern Denmark by von Huth, Sebastian, Lillevang, Søren Thue, Røge, Birgit Thorup, Madsen, Jonna Skov, Mogensen, Christian Backer, Coia, John Eugenio, Möller, Sören, Justesen, Ulrik Stenz, Johansen, Isik Somuncu

“…●Healthcare workers carry a pronounced risk of acquiring SARS-CoV-2 infection.●The seroprevalence of SARS-CoV-2 antibodies was 2.1% among 7950…”
Get full text

Two cases of erythema induratum of Bazin – a rare cutaneous manifestation of tuberculosis by von Huth, Sebastian, Øvrehus, Anne Lindebo, Lindahl, Kim Hein, Johansen, Isik Somuncu

“…Highlights • We describe two cases of erythema induratum of Bazin (EIB), a cutaneous form of TB • Cases had no signs of active TB, but had a positive…”
Get full text

Biological effect of laser‐assisted scar healing (LASH) on standardized human three‐dimensional wound healing skin models using fractional non‐ablative 1540nm Er:Glass or 1550nm diode lasers by Riedemann, Helena I, Marquardt, Yvonne, Jansen, Manuela, Baron, Jens M, Huth, Sebastian

“…PurposeIn postoperative wound healing after surgical operations or ablative laser treatments, recent studies suggest the timely use of non‐ablative fractional…”
Get full text

Biological effect of laser‐assisted scar healing (LASH) on standardized human three‐dimensional wound healing skin models using fractional non‐ablative 1540 nm Er:Glass or 1550 nm diode lasers by Riedemann, Helena I., Marquardt, Yvonne, Jansen, Manuela, Baron, Jens M., Huth, Sebastian

“…Purpose In postoperative wound healing after surgical operations or ablative laser treatments, recent studies suggest the timely use of non‐ablative fractional…”
Get full text

MMP-3 plays a major role in calcium pantothenate-promoted wound healing after fractional ablative laser treatment by Huth, Sebastian, Huth, Laura, Marquardt, Yvonne, Cheremkhina, Maria, Heise, Ruth, Baron, Jens Malte

“…Ablative fractional laser treatment leads to a loss of matrix metalloproteinase-3 (MMP-3) expression; therefore, in the present in vitro study, we addressed…”
Get full text

Prevalence and potential risk factors for gastrointestinal parasitic infections in children in urban Bissau, Guinea-Bissau by von Huth, Sebastian, Kofoed, Poul-Erik, Holmskov, Uffe

“…Gastrointestinal (GI) parasitic infections cause significant morbidity and mortality in tropical and subtropical countries. We aimed to investigate the…”
Get full text

Pathological mutations reveal the key role of the cytosolic iRhom2 N-terminus for phosphorylation-independent 14-3-3 interaction and ADAM17 binding, stability, and activity by Bläsius, Katharina, Ludwig, Lena, Knapp, Sarah, Flaßhove, Charlotte, Sonnabend, Friederike, Keller, Diandra, Tacken, Nikola, Gao, Xintong, Kahveci-Türköz, Selcan, Grannemann, Caroline, Babendreyer, Aaron, Adrain, Colin, Huth, Sebastian, Baron, Jens Malte, Ludwig, Andreas, Düsterhöft, Stefan

“…The protease ADAM17 plays an important role in inflammation and cancer and is regulated by iRhom2. Mutations in the cytosolic N-terminus of human iRhom2 cause…”
Get full text

Immunohistochemical Localization of Deleted in Malignant Brain Tumors 1 in Normal Human Tissues by Bathum Nexoe, Anders, Pedersen, Andreas Arnholdt, von Huth, Sebastian, Detlefsen, Sönke, Hansen, Pernille Lund, Holmskov, Uffe

“…Deleted in malignant brain tumors 1 (DMBT1) is part of the innate immune system and is expressed on mucosal surfaces in various tissues throughout the human…”
Get full text

Understanding the impact of risankizumab on keratinocyte-derived IL-23A in a novel organotypic 3D skin model containing IL-23A responsive and IL-17A producing γδ-T-cells by Huth, Laura, Amann, Philipp M, Marquardt, Yvonne, Jansen, Manuela, Baron, Jens Malte, Huth, Sebastian

“…PurposeTo study the effects of the anti-IL-23A antibody risankizumab on the IL-36γ/IL-23A/IL-17A signaling cascade we used a newly developed 3D skin model…”
Get full text

Molecular effects of photon irradiation and subsequent aftercare treatment with dexpanthenol‐containing ointment or liquid in 3D models of human skin and non‐keratinized oral mucosa by Huth, Sebastian, Marquardt, Yvonne, Huth, Laura, Schmitt, Laurenz, Prescher, Kirsten, Winterhalder, Philipp, Steiner, Timm, Hölzle, Frank, Eble, Michael, Malte Baron, Jens

“…This study aimed to investigate the molecular effects of radiation and subsequent aftercare treatment with dexpanthenol‐containing ointment and liquid on…”
Get full text