Search Results - "Huth, Laura"
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Comprehensive molecular characterization of microneedling therapy in a human three-dimensional skin model
Published in PloS one (20-09-2018)“…Microneedling therapy is a widely used technique in dermatology. However, little is known about the underlying molecular effects of this therapy on…”
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Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are significant promotors of UVB- but not chemically induced non-melanoma skin cancer
Published in Scientific reports (18-07-2023)“…Non-melanoma skin cancer (NMSC) is the most common cancer in Caucasians worldwide. We investigated the pathophysiological role of MIF and its homolog D-DT in…”
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Adaptation of Staphylococcus aureus to the Human Skin Environment Identified Using an ex vivo Tissue Model
Published in Frontiers in microbiology (21-09-2021)“…The healthy human epidermis provides physical protection and is impenetrable for pathogenic microbes. Nevertheless, commensal and pathogen bacteria such as…”
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BDNF is associated with SFRP1 expression in luminal and basal-like breast cancer cell lines and primary breast cancer tissues: a novel role in tumor suppression?
Published in PloS one (18-07-2014)“…Secreted frizzled related protein 1 (SFRP1) functions as an important inhibitor of the Wnt pathway and is a known tumor suppressor gene, which is…”
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High Fidelity Simulation with Peer Debriefing: Influence of Student Observation and Participation Roles on Student Perception of Confidence with Learning and Feedback
Published in Journal of occupational therapy education (01-04-2020)“…High fidelity simulation (HFS) has been used successfully to prepare students in a range of health professions for the acute care setting. HFS consists of…”
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Establishment of an Intradermal Ear Injection Model of IL-17A and IL-36γ as a Tool to Investigate the Psoriatic Cytokine Network
Published in Life (Basel, Switzerland) (19-08-2021)“…Psoriasis is a chronic skin disease affecting 2–3% of the global population. The proinflammatory IL-17A is a key cytokine in psoriasis. Accumulating evidence…”
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A Milestone-Based Evaluation System — The Cure for Grade Inflation?
Published in Journal of surgical education (01-11-2015)“…Purpose Controversy exists over the optimal use of the Milestones in the process of resident evaluation and feedback. We sought to evaluate the performance of…”
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MMP-3 plays a major role in calcium pantothenate-promoted wound healing after fractional ablative laser treatment
Published in Lasers in medical science (01-03-2022)“…Ablative fractional laser treatment leads to a loss of matrix metalloproteinase-3 (MMP-3) expression; therefore, in the present in vitro study, we addressed…”
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Understanding the impact of risankizumab on keratinocyte-derived IL-23A in a novel organotypic 3D skin model containing IL-23A responsive and IL-17A producing γδ-T-cells
Published in Cutaneous and ocular toxicology (02-04-2024)“…PurposeTo study the effects of the anti-IL-23A antibody risankizumab on the IL-36γ/IL-23A/IL-17A signaling cascade we used a newly developed 3D skin model…”
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Molecular effects of photon irradiation and subsequent aftercare treatment with dexpanthenol‐containing ointment or liquid in 3D models of human skin and non‐keratinized oral mucosa
Published in Experimental dermatology (01-05-2021)“…This study aimed to investigate the molecular effects of radiation and subsequent aftercare treatment with dexpanthenol‐containing ointment and liquid on…”
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Deciphering the molecular effects of non-ablative Er:YAG laser treatment in an in vitro model of the non-keratinized mucous membrane
Published in Lasers in medical science (01-07-2021)Get full text
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Molecular Diagnostic Applications in Colorectal Cancer
Published in Microarrays (Basel, Switzerland) (26-06-2014)“…Colorectal cancer, a clinically diverse disease, is a leading cause of cancer-related death worldwide. Application of novel molecular diagnostic tests, which…”
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Bifonazole Exerts Anti-Inflammatory Effects in Human Three-Dimensional Skin Equivalents after UVB or Histamine Challenge
Published in Skin pharmacology and physiology (01-11-2019)“…In addition to its role as a broad-spectrum imidazole antifungal drug, data from animal models as well as human clinical trials also demonstrated an…”
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Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial
Published in Cutaneous and ocular toxicology (03-07-2019)“…Background: Laser therapy with an ablative CO 2 laser is a prominent treatment option for photo-damaged skin. The healing process and therefore the success of…”
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Novel Human Full-Thickness Three-Dimensional Nonkeratinized Mucous Membrane Model for Pharmacological Studies in Wound Healing
Published in Skin pharmacology and physiology (01-01-2019)“…Efforts are increasingly aiming to develop in vitro models that can provide effective alternatives to in vivo experiments. The main aim of this study was the…”
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Impact of Surgery Program Characteristics on Fate of Non-designated Preliminary Surgery Interns
Published in Journal of surgical education (01-11-2020)“…•Over 65% of nondesignated preliminary interns obtain categorical residency positions.•Standardized testing scores are predictive of nondesignated preliminary…”
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Accelerated wound healing with a dexpanthenol-containing ointment after fractional ablative CO 2 laser resurfacing of photo-damaged skin in a randomized prospective clinical trial
Published in Cutaneous and ocular toxicology (01-09-2019)“…Laser therapy with an ablative CO laser is a prominent treatment option for photo-damaged skin. The healing process and therefore the success of a laser can be…”
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Molecular Diagnostic Applications in Colorectal Cancer
Published in Microarrays (01-09-2014)“…Colorectal cancer, a clinically diverse disease, is a leading cause of cancer-related death worldwide. Application of novel molecular diagnostic tests, which…”
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