Search Results - "Hutchinson, Sharon J."
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1
Prioritization of HCV treatment in the direct-acting antiviral era: An economic evaluation
Published in Journal of hepatology (01-07-2016)“…Graphical abstract…”
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Toward a more complete understanding of the association between a hepatitis C sustained viral response and cause‐specific outcomes
Published in Hepatology (Baltimore, Md.) (01-08-2015)“…Sustained viral response (SVR) is the optimal outcome of hepatitis C virus (HCV) therapy, yet more detailed data are required to confirm its clinical value…”
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Rapid decline in HCV incidence among people who inject drugs associated with national scale-up in coverage of a combination of harm reduction interventions
Published in PloS one (11-08-2014)“…Government policy has precipitated recent changes in the provision of harm reduction interventions - injecting equipment provision (IEP) and opiate…”
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Mortality in hepatitis C patients who achieve a sustained viral response compared to the general population
Published in Journal of hepatology (01-01-2017)“…Graphical abstract…”
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Laying the foundations for hepatitis C elimination: evaluating the development and contribution of community care pathways to diagnostic efforts
Published in BMC public health (07-01-2023)“…Hepatitis C Virus (HCV) is a public health threat which contributes substantially to the global burden of liver disease. There is much debate about effective…”
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The Hep-CORE policy score: A European hepatitis C national policy implementation ranking based on patient organization data
Published in PloS one (28-07-2020)“…New hepatitis C virus (HCV) treatments spurred the World Health Organization (WHO) in 2016 to adopt a strategy to eliminate HCV as a public health threat by…”
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Drugs-Related Death Soon after Hospital-Discharge among Drug Treatment Clients in Scotland: Record Linkage, Validation, and Investigation of Risk-Factors
Published in PloS one (05-11-2015)“…We validate that the 28 days after hospital-discharge are high-risk for drugs-related death (DRD) among drug users in Scotland and investigate key risk-factors…”
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Detection of hepatitis C virus RNA in dried blood spots
Published in Journal of clinical virology (01-06-2012)“…Abstract Background An estimated 130–170 million people worldwide are chronically infected with HCV. In Europe the highest prevalence of HCV infections is in…”
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Modeling the current and future disease burden of hepatitis C among injection drug users in Scotland
Published in Hepatology (Baltimore, Md.) (01-09-2005)“…Quantitative estimates of the current and future burden of hepatitis C virus (HCV) disease are required to plan a public health response to the HCV epidemic…”
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Competing Risk Bias in Prognostic Models Predicting Hepatocellular Carcinoma Occurrence: Impact on Clinical Decision-making
Published in Gastro hep advances (2022)“…Existing models predicting hepatocellular carcinoma (HCC) occurrence do not account for competing risk events and, thus, may overestimate the probability of…”
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Combination Interventions to Prevent HCV Transmission Among People Who Inject Drugs: Modeling the Impact of Antiviral Treatment, Needle and Syringe Programs, and Opiate Substitution Therapy
Published in Clinical infectious diseases (15-08-2013)“…Background. Interventions such as opiate substitution therapy (OST) and high-coverage needle and syringe programs (HCNSP) cannot substantially reduce hepatitis…”
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The Central Scotland Escherichia coli O157:H7 Outbreak: Risk Factors for the Hemolytic Uremic Syndrome and Death among Hospitalized Patients
Published in Clinical infectious diseases (01-10-2001)“…Little is known about risk factors for complications of Escherichia coli O157:H7 infection in adults. The 1996 outbreak in central Scotland involved the…”
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Are needle and syringe programmes associated with a reduction in HIV transmission among people who inject drugs: a systematic review and meta-analysis
Published in International journal of epidemiology (01-02-2014)“…Needle and syringe programmes (NSP) aim to reduce the risk of HIV by providing people who inject drugs (PWID) with sterile injecting equipment. A recent review…”
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The seroprevalence of hepatitis C virus infection among children and their mothers attending for dental care in Glasgow, Scotland, United Kingdom
Published in Journal of infection and public health (01-07-2017)“…Summary This paper describes a voluntary anonymous survey to investigate the seroprevalence of Hepatitis C (HCV) in children in Glasgow, UK attending a Dental…”
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Treatment of Hepatitis C Virus Infection Among People Who Are Actively Injecting Drugs: A Systematic Review and Meta-analysis
Published in Clinical infectious diseases (15-08-2013)“…Background. Although guidelines recommend that people who inject drugs (PWID) should not be excluded from hepatitis C (HCV) treatment, some services remain…”
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Hepatitis C virus treatment for prevention among people who inject drugs: Modeling treatment scale‐up in the age of direct‐acting antivirals
Published in Hepatology (Baltimore, Md.) (01-11-2013)“…Substantial reductions in hepatitis C virus (HCV) prevalence among people who inject drugs (PWID) cannot be achieved by harm reduction interventions such as…”
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The contribution of health risk behaviors to excess mortality in American adults with chronic hepatitis C: A population cohort‐study
Published in Hepatology (Baltimore, Md.) (01-01-2018)“…In resource‐rich countries, chronic hepatitis C (CHC) infection is associated with a sizeable excess mortality risk. The extent to which this is due to (1) the…”
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aMAP risk score predicts hepatocellular carcinoma development in patients with chronic hepatitis
Published in Journal of hepatology (01-12-2020)“…Hepatocellular carcinoma (HCC) is the leading cause of death in patients with chronic hepatitis. In this international collaboration, we sought to develop a…”
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Strategies for the treatment of Hepatitis C in an era of interferon-free therapies: what public health outcomes do we value most?
Published in Gut (01-11-2015)“…The expense of new therapies for HCV infection may force health systems to prioritise the treatment of certain patient groups over others. Our objective was to…”
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Suicide in people prescribed opioid-agonist therapy in Scotland, United Kingdom, 2011-2020: A national retrospective cohort study
Published in Addiction (Abingdon, England) (22-10-2024)“…Opioid dependence is associated with an increased risk of suicide. Drug-related mortality among people with opioid dependence in Scotland has more than tripled…”
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