Search Results - "Hutchinson, J. A"
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Ultrasound non-invasive measurement of intracranial pressure in neurointensive care: A prospective observational study
Published in PLoS medicine (25-07-2017)“…The invasive nature of the current methods for monitoring of intracranial pressure (ICP) has prevented their use in many clinical situations. Several attempts…”
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Peptide hormones and lipopeptides: from self‐assembly to therapeutic applications
Published in Journal of peptide science (01-02-2017)“…This review describes the properties and activities of lipopeptides and peptide hormones and how the lipidation of peptide hormones could potentially produce…”
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3
The cytokine response to human traumatic brain injury: temporal profiles and evidence for cerebral parenchymal production
Published in Journal of cerebral blood flow and metabolism (01-02-2011)“…The role of neuroinflammation is increasingly being recognised in a diverse range of cerebral pathologies, including traumatic brain injury (TBI). We used…”
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4
The reporting of study and population characteristics in degenerative cervical myelopathy: A systematic review
Published in PloS one (01-03-2017)“…Degenerative cervical myelopathy [DCM] is a disabling and increasingly prevalent condition. Variable reporting in interventional trials of study design and…”
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Reported Outcome Measures in Degenerative Cervical Myelopathy: A Systematic Review
Published in PloS one (02-08-2016)“…Degenerative cervical myelopathy [DCM] is a disabling and increasingly prevalent group of diseases. Heterogeneous reporting of trial outcomes limits effective…”
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Early neuro-rehabilitation in traumatic brain injury: the need for an African perspective
Published in BMC medicine (04-08-2023)“…Traumatic brain injury (TBI) is a global public health challenge, affecting about 69 million individuals annually and being one of the leading causes of…”
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Systemic inflammation alters the neuroinflammatory response: a prospective clinical trial in traumatic brain injury
Published in Journal of neuroinflammation (25-09-2021)“…Neuroinflammation following traumatic brain injury (TBI) has been shown to be associated with secondary injury development; however, how systemic inflammatory…”
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Improved long-term survival with subdural drains following evacuation of chronic subdural haematoma
Published in Acta neurochirurgica (01-05-2017)“…Background Chronic subdural haematoma (CSDH) is a common condition that is effectively managed by burrhole drainage but requires repeat surgery in a…”
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An exploratory qualitative study of the prevention of road traffic collisions and neurotrauma in India: perspectives from key informants in an Indian industrial city (Visakhapatnam)
Published in BMC public health (30-03-2021)“…Despite current preventative strategies, road traffic collisions (RTCs) and resultant neurotrauma remain a major problem in India. This study seeks to explore…”
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Use of T2-weighted magnetic resonance imaging of the optic nerve sheath to detect raised intracranial pressure
Published in Critical care (London, England) (01-01-2008)“…The dural sheath surrounding the optic nerve communicates with the subarachnoid space, and distends when intracranial pressure is elevated. Magnetic resonance…”
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Twenty-Five Years of Intracranial Pressure Monitoring After Severe Traumatic Brain Injury: A Retrospective, Single-Center Analysis
Published in Neurosurgery (01-07-2019)“…Abstract BACKGROUND Intracranial pressure (ICP) is a clinically important variable after severe traumatic brain injury (TBI) and has been monitored, along with…”
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Geomagnetic storms over the last solar cycle: A superposed epoch analysis
Published in Journal of Geophysical Research: Space Physics (01-09-2011)“…Presented here is a discussion of the results of a superposed epoch analysis of geomagnetic storms over the last solar cycle. Storms, identified by means of…”
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13
Traumatic Brain Injury in Cameroon: A Prospective Observational Study in a Level I Trauma Centre
Published in Medicina (Kaunas, Lithuania) (01-08-2023)“…Background and Objective: About 14 million people will likely suffer a traumatic brain injury (TBI) per year by 2050 in sub-Saharan Africa. Studying TBI…”
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Modelling of Brain Deformation After Decompressive Craniectomy
Published in Annals of biomedical engineering (01-12-2016)“…Hyperelastic finite element models, with either an idealized cylindrical geometry or with realistic craniectomy geometries, were used to explore clinical…”
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Development of a finite element model of decompressive craniectomy
Published in PloS one (15-07-2014)“…Decompressive craniectomy (DC), an operation whereby part of the skull is removed, is used in the management of patients with brain swelling. While the aim of…”
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Mapping global evidence on strategies and interventions in neurotrauma and road traffic collisions prevention: a scoping review
Published in Systematic reviews (20-05-2020)“…Neurotrauma is an important global health problem. The largest cause of neurotrauma worldwide is road traffic collisions (RTCs), particularly in low- and…”
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Succinate supplementation improves metabolic performance of mixed glial cell cultures with mitochondrial dysfunction
Published in Scientific reports (21-04-2017)“…Mitochondrial dysfunction, the inability to efficiently utilise metabolic fuels and oxygen, contributes to pathological changes following traumatic spinal cord…”
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Fracturing of an Euler–Bernoulli beam in coal mine pillar extraction
Published in International journal of rock mechanics and mining sciences (Oxford, England : 1997) (01-12-2013)“…The paper models the first stage of the process of pillar extraction in a coal mine. The problem of understanding how a coal mine roof collapses after…”
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Monitoring the Neuroinflammatory Response Following Acute Brain Injury
Published in Frontiers in neurology (20-07-2017)“…Traumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) are major contributors to morbidity and mortality. Following the initial insult, patients may…”
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Prevention of road traffic collisions and associated neurotrauma in Colombia: An exploratory qualitative study
Published in PloS one (25-03-2021)“…Neurotrauma is an important but preventable cause of death and disability worldwide, with the majority being associated with road traffic collisions (RTCs)…”
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