Search Results - "Hutchinson, E Gail"

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  1. 1

    Snakebite and its socio-economic impact on the rural population of Tamil Nadu, India by Vaiyapuri, Sakthivel, Vaiyapuri, Rajendran, Ashokan, Rajesh, Ramasamy, Karthikeyan, Nattamaisundar, Kameshwaran, Jeyaraj, Anburaj, Chandran, Viswanathan, Gajjeraman, Prabu, Baksh, M Fazil, Gibbins, Jonathan M, Hutchinson, E Gail

    Published in PloS one (21-11-2013)
    “…Snakebite represents a significant health issue worldwide, affecting several million people each year with as many as 95,000 deaths. India is considered to be…”
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  2. 2

    Evolutionary analysis of novel serine proteases in the venom gland transcriptome of Bitis gabonica rhinoceros by Vaiyapuri, Sakthivel, Wagstaff, Simon C, Harrison, Robert A, Gibbins, Jonathan M, Hutchinson, E Gail

    Published in PloS one (24-06-2011)
    “…Serine proteases are major components of viper venom and target various stages of the blood coagulation system in victims and prey. A better understanding of…”
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  3. 3

    Purification and functional characterisation of rhiminopeptidase A, a novel aminopeptidase from the venom of Bitis gabonica rhinoceros by Vaiyapuri, Sakthivel, Wagstaff, Simon C, Watson, Kimberley A, Harrison, Robert A, Gibbins, Jonathan M, Hutchinson, E Gail

    Published in PLoS neglected tropical diseases (01-08-2010)
    “…Snake bite is a major neglected public health issue within poor communities living in the rural areas of several countries throughout the world. An estimated…”
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  4. 4

    A Designed System for Assessing How Sequence Affects α to β Conformational Transitions in Proteins by Ciani, Barbara, Hutchinson, E. Gail, Sessions, Richard B., Woolfson, Derek N.

    Published in The Journal of biological chemistry (22-03-2002)
    “…The role of amino acid sequence in conformational switching observed in prions and proteins associated with amyloid diseases is not well understood. To study α…”
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  5. 5

    Stereochemical quality of protein structure coordinates by Morris, A L, MacArthur, M W, Hutchinson, E G, Thornton, J M

    “…Methods have been developed to assess the stereochemical quality of any protein structure both globally and locally using various criteria. Several parameters…”
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  6. 6

    Toward Predicting Protein Topology: An Approach to Identifying β Hairpins by de la Cruz, Xavier, Hutchinson, E. Gail, Shepherd, Adrian, Thornton, Janet M.

    “…Although secondary structure prediction methods have recently improved, progress from secondary to tertiary structure prediction has been limited. A promising…”
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  7. 7

    Barrel structures in proteins: Automatic identification and classification including a sequence analysis of TIM barrels by NAGANO, NOZOMI, HUTCHINSON, E. GAIL, THORNTON, JANET M.

    Published in Protein science (01-10-1999)
    “…Automated methods for identifying and characterizing regular β-barrels from coordinate data have been developed to analyze and classify various kinds of barrel…”
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  8. 8

    Rhinocetin, a Venom-derived Integrin-specific Antagonist Inhibits Collagen-induced Platelet and Endothelial Cell Functions by Vaiyapuri, Sakthivel, Hutchinson, E. Gail, Ali, Marfoua S., Dannoura, Abeer, Stanley, Ronald G., Harrison, Robert A., Bicknell, Andrew B., Gibbins, Jonathan M.

    Published in The Journal of biological chemistry (27-07-2012)
    “…Background: Snaclecs affect the hemostasis of snakebite victims upon envenomation. Results: Rhinocetin, a novel snaclec, inhibits integrin α2β1-dependent…”
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  9. 9

    PROMOTIF—A program to identify and analyze structural motifs in proteins by Hutchinson, E. Gail, Thornton, Janet M.

    Published in Protein science (01-02-1996)
    “…We describe a suite of programs, PROMOTIF, that analyzes a protein coordinate file and provides details about the structural motifs in the protein. The program…”
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  10. 10

    Sequence and phylogenetic analysis of viper venom serine proteases by Vaiyapuri, Sakthivel, Thiyagarajan, Nethaji, Hutchinson, E Gail, Gibbins, Jonathan M

    Published in Bioinformation (01-01-2012)
    “…Snakebites are a major neglected tropical disease responsible for as many as 95000 deaths every year worldwide. Viper venom serine proteases disrupt…”
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  11. 11

    Protein folds and functions by Martin, Andrew CR, Orengo, Christine A, Hutchinson, E Gail, Jones, Susan, Karmirantzou, Maria, Laskowski, Roman A, Mitchell, John BO, Taroni, Chiara, Thornton, Janet M

    Published in Structure (London) (15-07-1998)
    “…Background: The recent rapid increase in the number of available three-dimensional protein structures has further highlighted the necessity to understand the…”
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  12. 12

    Identification, classification, and analysis of beta‐bulges in proteins by Chan, A. W. Edith, Hutchinson, E. Gail, Harris, Daniel, Thornton, Janet M.

    Published in Protein science (01-10-1993)
    “…A β‐bulge is a region of irregularity in a β‐sheet involving two β‐strands. It usually involves two or more residues in the bulged strand opposite to a single…”
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  13. 13

    Negative Social Experiences of University and College Students by Tremblay, Paul F, Harris, Roma, Berman, Helene, MacQuarrie, Barb, Hutchinson, Gail E, Smith, Mary Ann, Braley, Susan, Jelley, Jennifer, Dearlove, Kristen

    “…Dans cet article, nous étudions les conflits interpersonnels et l'exposition à l'abus et à la violence des étudiantes et étudiants canadiens des niveaux…”
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  14. 14

    Contemporary approaches to protein structure classification by Swindells, Mark B., Orengo, Christine A., Jones, David T., Hutchinson, E. Gail, Thornton, Janet M.

    Published in BioEssays (01-11-1998)
    “…In a similar manner to sequence database searching, it is also possible to compare three‐dimensional protein structures. Such methods can be extremely useful…”
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  15. 15

    HERA--a program to draw schematic diagrams of protein secondary structures by Hutchinson, E G, Thornton, J M

    “…A program is described which generates hydrogen bonding diagrams of protein structures and optionally helical wheels and helical nets. The program can also…”
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  16. 16

    A revised set of potentials for β‐turn formation in proteins by Hutchinson, E. Gail, Thornton, Janet M.

    Published in Protein science (01-12-1994)
    “…Three thousand eight hundred ninety‐nine β‐turns have been identified and classified using a nonhomologous data set of 205 protein chains. These were used to…”
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    Characterization of a Serine Protease that Cleaves Pro-γ-Melanotropin at the Adrenal to Stimulate Growth by Bicknell, Andrew B., Lomthaisong, Khomsorn, Woods, Russell J., Hutchinson, E.Gail, Bennett, Hugh P.J., Gladwell, Richard T., Lowry, Philip J.

    Published in Cell (29-06-2001)
    “…The adrenal gland requires stimuli from peptides derived from the ACTH precursor, pro-opiomelanocortin (POMC), to maintain its tonic state. Studies have…”
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  19. 19

    Sequence and phylogenetic analysis of viper venom serine proteases by Vaiyapuri, Sakthivel, Thiyagarajan, Nethaji, Hutchinson, E Gail, Gibbins, Jonathan M

    Published in Bioinformation (24-08-2012)
    “…Snakebites are a major neglected tropical disease responsible for as many as 95000 deaths every year worldwide. Viper venom serine proteases disrupt…”
    Get full text
    Journal Article
  20. 20

    Determinants of strand register in antiparallel β‐sheets of proteins by Hutchinson, E. Gail, Sessions, Richard B., Thornton, Janet M., Woolfson, Derek N.

    Published in Protein science (01-11-1998)
    “…Antiparallel β‐sheets present two distinct environments to inter‐strand residue pairs: βA, HB sites have two backbone hydrogen bonds; whereas at βA, NHB…”
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