Search Results - "Hutchins, G"

Swarm learning for decentralized artificial intelligence in cancer histopathology by Saldanha, Oliver Lester, Quirke, Philip, West, Nicholas P., James, Jacqueline A., Loughrey, Maurice B., Grabsch, Heike I., Salto-Tellez, Manuel, Alwers, Elizabeth, Cifci, Didem, Ghaffari Laleh, Narmin, Seibel, Tobias, Gray, Richard, Hutchins, Gordon G. A., Brenner, Hermann, van Treeck, Marko, Yuan, Tanwei, Brinker, Titus J., Chang-Claude, Jenny, Khader, Firas, Schuppert, Andreas, Luedde, Tom, Trautwein, Christian, Muti, Hannah Sophie, Foersch, Sebastian, Hoffmeister, Michael, Truhn, Daniel, Kather, Jakob Nikolas

“…Artificial intelligence (AI) can predict the presence of molecular alterations directly from routine histopathology slides. However, training robust AI systems…”
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Systemic neutrophil-to-lymphocyte ratio in colorectal cancer: the relationship to patient survival, tumour biology and local lymphocytic response to tumour by Pine, J K, Morris, E, Hutchins, G G, West, N P, Jayne, D G, Quirke, P, Prasad, K R

“…Background: Colorectal cancer (CRC) is a major cause of mortality and morbidity. The impact of inflammatory biomarkers (C-reactive protein etc.) on CRC is…”
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A comparison of five high-resolution spatially-explicit, fossil-fuel, carbon dioxide emission inventories for the United States by Hutchins, Maya G., Colby, Jeffrey D., Marland, Gregg, Marland, Eric

“…The quantification of fossil-fuel-related emissions of carbon dioxide to the atmosphere is necessary in order to accurately represent carbon cycle fluxes and…”
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Epstein-Barr virus and mismatch repair deficiency status differ between oesophageal and gastric cancer: A large multi-centre study by Hewitt, L.C., Inam, I.Z., Saito, Y., Yoshikawa, T., Quaas, A., Hoelscher, A., Bollschweiler, E., Fazzi, G.E., Melotte, V., Langley, R.E., Nankivell, M., Cunningham, D., Allum, W., Hutchins, G.G., Grabsch, H.I.

“…Oesophageal (OeC) and gastric (GC) cancer patients are treated with similar multimodal therapy and have poor survival. There remains an urgent clinical need to…”
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What impact might mitigation of diffuse nitrate pollution have on river water quality in a rural catchment? by Hutchins, Michael G.

“…Observations of river flow, river quality and solar radiation were collated to assess the degree to which light and nutrients may be limiting phytoplankton…”
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The proportion of tumour cells is an independent predictor for survival in colorectal cancer patients by West, N P, Dattani, M, McShane, P, Hutchins, G, Grabsch, J, Mueller, W, Treanor, D, Quirke, P, Grabsch, H

“…Background: The proportion of epithelial and stromal cells in tumours is thought to have an important role in the progression of epithelial malignancy. We…”
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Assessment of myocardial metabolic flexibility and work efficiency in human type 2 diabetes using 16-[18F]fluoro-4-thiapalmitate, a novel PET fatty acid tracer by Mather, K J, Hutchins, G D, Perry, K, Territo, W, Chisholm, R, Acton, A, Glick-Wilson, B, Considine, R V, Moberly, S, DeGrado, T R

“…Altered myocardial fuel selection likely underlies cardiac disease risk in diabetes, affecting oxygen demand and myocardial metabolic flexibility. We…”
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In situ validation of an intestinal stem cell signature in colorectal cancer by Ziskin, Jennifer L, Dunlap, Debra, Yaylaoglu, Murat, Fodor, Imola K, Forrest, William F, Patel, Rajesh, Ge, Nianfeng, Hutchins, Gordon G, Pine, James K, Quirke, Philip, Koeppen, Hartmut, Jubb, Adrian M

“…Wnt/Tcf, Lgr5, Ascl2 and/or Bmi1 signalling is believed to define the mouse intestinal stem cell niche(s) from which adenomas arise. The aim of this study was…”
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Why scale is vital to plan optimal Nature-Based Solutions for resilient cities by Hutchins, MG, Fletcher, D, Hagen-Zanker, A, Jia, H, Jones, L, Li, H, Loiselle, S, Miller, J, Reis, S, Seifert-Dähnn, I, Wilde, V, Xu, C-Y, Yang, D, Yu, J, Yu, S

“…Abstract A need for multi-functional assessment tools evaluating trade-offs and co-benefits for various types of Nature-Based Solutions (NBS) has been…”
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A case–control study of the pathology of oesophageal disease in systemic sclerosis (scleroderma) by Roberts, C G P, Hummers, L K, Ravich, W J, Wigley, F M, Hutchins, G M

“…Background: Atrophy of the smooth muscle layers of the muscularis propria characterises oesophageal involvement in systemic sclerosis (scleroderma). The…”
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Artificial intelligence for detection of microsatellite instability in colorectal cancer—a multicentric analysis of a pre-screening tool for clinical application by Echle, A., Ghaffari Laleh, N., Quirke, P., Grabsch, H.I., Muti, H.S., Saldanha, O.L., Brockmoeller, S.F., van den Brandt, P.A., Hutchins, G.G.A., Richman, S.D., Horisberger, K., Galata, C., Ebert, M.P., Eckardt, M., Boutros, M., Horst, D., Reissfelder, C., Alwers, E., Brinker, T.J., Langer, R., Jenniskens, J.C.A., Offermans, K., Mueller, W., Gray, R., Gruber, S.B., Greenson, J.K., Rennert, G., Bonner, J.D., Schmolze, D., Chang-Claude, J., Brenner, H., Trautwein, C., Boor, P., Jaeger, D., Gaisa, N.T., Hoffmeister, M., West, N.P., Kather, J.N.

“…Microsatellite instability (MSI)/mismatch repair deficiency (dMMR) is a key genetic feature which should be tested in every patient with colorectal cancer…”
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Long-Term Outcome of Fulminant Myocarditis as Compared with Acute (Nonfulminant) Myocarditis by McCarthy, Robert E, Boehmer, John P, Hruban, Ralph H, Hutchins, Grover M, Kasper, Edward K, Hare, Joshua M, Baughman, Kenneth L

“…Lymphocytic myocarditis remains a poorly characterized disorder. Approximately 10 percent of patients with cardiomyopathy of recent onset who undergo…”
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Filamin A mutations cause periventricular heterotopia with Ehlers-Danlos syndrome by SHEEN, V. L, JANSEN, A, VAID, R. R, RUIZ, D. E, HUTCHINS, G. M, MENASHA, J, WILLNER, J, GENG, Y, GRIPP, K. W, NICHOLSON, L, BERRY-KRAVIS, E, BODELL, A, CHEN, M. H, APSE, K, HILL, R. S, DUBEAU, F, ANDERMANN, F, BARKOVICH, J, ANDERMANN, E, SHUGART, Y. Y, THOMAS, P, VIRI, M, VEGGIOTTI, P, PARRINI, E, ROBERTSON, S, GUERRINI, R, WALSH, C. A, MORGAN, T, RAVENSCROFT, R, GANESH, V, UNDERWOOD, T, WILEY, J, LEVENTER, R

“…To define the clinical, radiologic, and genetic features of periventricular heterotopia (PH) with Ehlers-Danlos syndrome (EDS). Exonic sequencing and single…”
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A study of persistent post-concussion symptoms in mild head trauma using positron emission tomography by Chen, S H A, Kareken, D A, Fastenau, P S, Trexler, L E, Hutchins, G D

“…Background: Complaints of persistent cognitive deficits following mild head trauma are often uncorroborated by structural brain imaging and neuropsychological…”
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Histological intratumoral heterogeneity in pretreatment esophageal cancer biopsies predicts survival benefit from neoadjuvant chemotherapy: results from the UK MRC OE02 trial by Davarzani, Naser, Hewitt, Lindsay C, Hale, Matthew D, Melotte, Veerle, Nankivell, Matthew, Hutchins, Gordon G A, Cunningham, David, Allum, William H, Langley, Ruth E, Jolani, Shahab, Grabsch, Heike I

“…Summary Despite the use of multimodal treatment, survival of esophageal cancer (EC) patients remains poor. One proposed explanation for the relatively poor…”
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Which offers more scope to suppress river phytoplankton blooms: Reducing nutrient pollution or riparian shading? by Hutchins, M.G., Johnson, A.C., Deflandre-Vlandas, A., Comber, S., Posen, P., Boorman, D.

“…River flow and quality data, including chlorophyll-a as a surrogate for river phytoplankton biomass, were collated for the River Ouse catchment in NE England,…”
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Coloenteric fistula in a young patient with recurrent diverticulitis: A case report and review of the literature by Ahmad, D S, Quist, E E, Hutchins, G F, Bhat, I

“…The development of colonic diverticula is common in developed countries and complications of colonic diverticulosis are responsible for a remarkable burden of…”
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Precision of 3.0 Tesla quantitative magnetic resonance imaging of cartilage morphology in a multicentre clinical trial by Eckstein, F, Buck, R J, Burstein, D, Charles, H C, Crim, J, Hudelmaier, M, Hunter, D J, Hutchins, G, Jackson, C, Kraus, V Byers, Lane, N E, Link, T M, Majumdar, L S, Mazzuca, S, Prasad, P V, Schnitzer, T J, Taljanovic, M S, Vaz, A, Wyman, B, Le Graverand, M-P Hellio

“…Quantitative MRI (qMRI) of cartilage morphology is a promising tool for disease-modifying osteoarthritis drug (DMOAD) development. Recent studies at single…”
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Commentary on Demetter et al by Quirke, P., Hutchins, G. G. A., West, N. P.

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Echocardiographic findings in fulminant and acute myocarditis by Felker, G.Michael, Boehmer, John P, Hruban, Ralph H, Hutchins, Grover M, Kasper, Edward K, Baughman, Kenneth L, Hare, Joshua M

“…OBJECTIVES We sought to use echocardiography to assess the presentation and potential for recovery of left ventricular (LV) function of patients with fulminant…”
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