Search Results - "Huston, Margaret M."

Nanoparticle‐Mediated Delivery of Anti‐PU.1 siRNA via Localized Intracisternal Administration Reduces Neuroinflammation by Ralvenius, William T., Andresen, Jason L., Huston, Margaret M., Penney, Jay, Bonner, Julia Maeve, Fenton, Owen S., Langer, Robert, Tsai, Li‐Huei

“…Neuroinflammation is a hallmark of neurodegenerative disorders including Alzheimer's disease (AD). Microglia, the brain's immune cells, express many of the…”
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A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation by Ralvenius, William T, Mungenast, Alison E, Woolf, Hannah, Huston, Margaret M, Gillingham, Tyler Z, Godin, Stephen K, Penney, Jay, Cam, Hugh P, Gao, Fan, Fernandez, Celia G, Czako, Barbara, Lightfoot, Yaima, Ray, William J, Beckmann, Adrian, Goate, Alison M, Marcora, Edoardo, Romero-Molina, Carmen, Ayata, Pinar, Schaefer, Anne, Gjoneska, Elizabeta, Tsai, Li-Huei

“…Pervasive neuroinflammation occurs in many neurodegenerative diseases, including Alzheimer's disease (AD). SPI1/PU.1 is a transcription factor located at a…”
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