Search Results - "Husson, Steven J."
-
1
The BET Family of Proteins Targets Moloney Murine Leukemia Virus Integration near Transcription Start Sites
Published in Cell reports (Cambridge) (01-11-2013)“…A hallmark of retroviral replication is integration of the viral genome into host cell DNA. This characteristic makes retrovirus-based vectors attractive…”
Get full text
Journal Article -
2
Rhodopsin optogenetic toolbox v2.0 for light-sensitive excitation and inhibition in Caenorhabditis elegans
Published in PloS one (01-02-2018)“…In optogenetics, rhodopsins were established as light-driven tools to manipulate neuronal activity. However, during long-term photostimulation using…”
Get full text
Journal Article -
3
Sensory Neuron Fates Are Distinguished by a Transcriptional Switch that Regulates Dendrite Branch Stabilization
Published in Neuron (Cambridge, Mass.) (24-07-2013)“…Sensory neurons adopt distinct morphologies and functional modalities to mediate responses to specific stimuli. Transcription factors and their downstream…”
Get full text
Journal Article -
4
Real-time multimodal optical control of neurons and muscles in freely behaving Caenorhabditis elegans
Published in Nature methods (01-02-2011)“…An optogenetic illumination system based on the use of a liquid crystal display projector and video tracking software is reported, which allows real-time…”
Get full text
Journal Article -
5
Optogenetic Analysis of a Nociceptor Neuron and Network Reveals Ion Channels Acting Downstream of Primary Sensors
Published in Current biology (08-05-2012)“…Nociception generally evokes rapid withdrawal behavior in order to protect the tissue from harmful insults. Most nociceptive neurons responding to mechanical…”
Get full text
Journal Article -
6
Specific expression of channelrhodopsin-2 in single neurons of Caenorhabditis elegans
Published in PloS one (30-08-2012)“…Optogenetic approaches using light-activated proteins like Channelrhodopsin-2 (ChR2) enable investigating the function of populations of neurons in live…”
Get full text
Journal Article -
7
A toxicogenomics approach to screen chlorinated flame retardants tris(2‐chloroethyl) phosphate and tris(2‐chloroisopropyl) phosphate for potential health effects
Published in Journal of applied toxicology (01-04-2018)“…Tris(2‐chloroethyl) phosphate (TCEP) is a pervasive flame retardant that has been identified as a chemical of concern given its health effects and therefore…”
Get full text
Journal Article -
8
Adipokinetic hormone signaling through the gonadotropin-releasing hormone receptor modulates egg-laying in Caenorhabditis elegans
Published in Proceedings of the National Academy of Sciences - PNAS (03-02-2009)“…In mammals, hypothalamic gonadotropin-releasing hormone (GnRH) is a neuropeptide that stimulates the release of gonadotropins from the anterior pituitary. The…”
Get full text
Journal Article -
9
Microbial light-activatable proton pumps as neuronal inhibitors to functionally dissect neuronal networks in C. elegans
Published in PloS one (16-07-2012)“…Essentially any behavior in simple and complex animals depends on neuronal network function. Currently, the best-defined system to study neuronal circuits is…”
Get full text
Journal Article -
10
Correction: Y-box-binding protein 1 supports the early and late steps of HIV replication
Published in PloS one (29-10-2020)“…[This corrects the article DOI: 10.1371/journal.pone.0200080.]…”
Get full text
Journal Article -
11
Y-box-binding protein 1 supports the early and late steps of HIV replication
Published in PloS one (11-07-2018)“…The human immunodeficiency virus (HIV) depends on cellular proteins, so-called cofactors, to complete its replication cycle. In search for new therapeutic…”
Get full text
Journal Article -
12
Defective processing of neuropeptide precursors in Caenorhabditis elegans lacking proprotein convertase 2 (KPC‐2/EGL‐3): mutant analysis by mass spectrometry
Published in Journal of neurochemistry (01-09-2006)“…Biologically active peptides are synthesized as larger inactive proprotein peptide precursors which are processed by the concerted action of a cascade of…”
Get full text
Journal Article -
13
Toxicogenomics of the flame retardant tris (2-butoxyethyl) phosphate in HepG2 cells using RNA-seq
Published in Toxicology in vitro (01-02-2018)“…Tris (2-butoxyethyl) phosphate (TBOEP) is a compound produced at high volume that is used as both a flame retardant and a plasticizer. It is persistent and…”
Get full text
Journal Article -
14
Neuropeptide GPCRs in C. elegans
Published in Frontiers in endocrinology (Lausanne) (2012)“…Like most organisms, the nematode Caenorhabditis elegans relies heavily on neuropeptidergic signaling. This tiny animal represents a suitable model system to…”
Get full text
Journal Article -
15
Identification of New Members of the (Short) Neuropeptide F Family in Locusts and Caenorhabditis elegans
Published in Annals of the New York Academy of Sciences (01-04-2009)“…Both the long and short neuropeptides F (NPF) represent important families of invertebrate neuropeptides that have been implicated in the regulation of…”
Get full text
Journal Article -
16
Discovery of a Cholecystokinin-Gastrin-Like Signaling System in Nematodes
Published in Endocrinology (Philadelphia) (01-06-2008)“…Members of the cholecystokinin (CCK)/gastrin family of peptides, including the arthropod sulfakinins, and their cognate receptors, play an important role in…”
Get full text
Journal Article -
17
Peptidomics: The integrated approach of MS, hyphenated techniques and bioinformatics for neuropeptide analysis
Published in Journal of separation science (01-02-2008)“…MS is currently one of the most important analytical techniques in biological and medical research. ESI and MALDI launched the field of MS into biology. The…”
Get full text
Journal Article -
18
Impaired processing of FLP and NLP peptides in carboxypeptidase E (EGL‐21)‐deficient Caenorhabditis elegans as analyzed by mass spectrometry
Published in Journal of neurochemistry (01-07-2007)“…Biologically active peptides are synthesized from inactive pre‐proproteins or peptide precursors by the sequential actions of processing enzymes. Proprotein…”
Get full text
Journal Article -
19
Functional Characterization of Three G Protein-coupled Receptors for Pigment Dispersing Factors in Caenorhabditis elegans
Published in The Journal of biological chemistry (30-05-2008)“…Here, we report the identification, cloning, and functional characterization of three Caenorhabditis elegans G protein-coupled pigment dispersing factor (PDF)…”
Get full text
Journal Article -
20
Mixture effects of copper, cadmium, and zinc on mortality and behavior of Caenorhabditis elegans
Published in Environmental toxicology and chemistry (01-01-2018)“…The toxicity effects of zinc (Zn), copper (Cu), and cadmium (Cd), both as single metals and in combination, were examined in the nematode Caenorhabditis…”
Get full text
Journal Article