Search Results - "Husson, Julien"
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Force generation upon T cell receptor engagement
Published in PloS one (10-05-2011)“…T cells are major players of adaptive immune response in mammals. Recognition of an antigenic peptide in association with the major histocompatibility complex…”
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Characterizing Cell Adhesion by Using Micropipette Aspiration
Published in Biophysical journal (21-07-2015)“…We have developed a technique to directly quantify cell-substrate adhesion force using micropipette aspiration. The micropipette is positioned perpendicular to…”
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Measuring Cell Viscoelastic Properties Using a Microfluidic Extensional Flow Device
Published in Biophysical journal (01-11-2016)“…The quantification of cellular mechanical properties is of tremendous interest in biology and medicine. Recent microfluidic technologies that infer cellular…”
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The Solution to the Streptavidin-Biotin Paradox: The Influence of History on the Strength of Single Molecular Bonds
Published in Biophysical journal (01-12-2005)“…In the past few years, many studies have attempted to measure the strength of a single molecular bond. In general, these experiments consisted in pulling on…”
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Force-generation and dynamic instability of microtubule bundles
Published in Proceedings of the National Academy of Sciences - PNAS (01-07-2008)“…Individual dynamic microtubules can generate pushing or pulling forces when their growing or shrinking ends are in contact with cellular objects such as the…”
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Measuring Cell Mechanical Properties Using Microindentation
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Quantifying cell mechanical properties is of interest to better understand both physiological and pathological cellular processes. Cell mechanical properties…”
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A Nanospring Named Erythrocyte. The Biomembrane Force Probe
Published in Cellular and molecular bioengineering (01-12-2008)“…The Biomembrane Force Probe, BFP, is a sensitive technique that allows the quantification of single molecular bonds. It is a versatile tool that can be used in…”
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Quantifying both viscoelasticity and surface tension: Why sharp tips overestimate cell stiffness
Published in Biophysical journal (16-01-2024)“…Quantifying the mechanical properties of cells is important to better understand how mechanics constrain cellular processes. Furthermore, because pathologies…”
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Big data analytics capability in healthcare operations and supply chain management: the role of green process innovation
Published in Annals of operations research (01-02-2024)“…Green approaches remain little disseminated in the healthcare sector despite growing interest in recent years from practitioners and researchers. Big Data…”
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Perpendicular to grain and shear mechanical properties of veneer-based elements glued from single veneer sheets recovered from three species of juvenile subtropical hardwood plantation logs
Published in European journal of wood and wood products (01-11-2018)“…This paper quantifies the mechanical properties perpendicular to the grain and in shear of glued rotary peeled veneers, as would be encountered in veneer-based…”
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Analyzing single-bond experiments: influence of the shape of the energy landscape and universal law between the width, depth, and force spectrum of the bond
Published in Physical review. E, Statistical, nonlinear, and soft matter physics (01-02-2008)“…Experimentalists who measure the rupture force of a single molecular bond usually pull on that bond at a constant speed, keeping the loading rate r=df/dt…”
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Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing
Published in Cell (24-03-2016)“…The immunological synapse formed between a cytotoxic T lymphocyte (CTL) and an infected or transformed target cell is a physically active structure capable of…”
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Clogging of a Rectangular Slit by a Spherical Soft Particle
Published in Physical review letters (10-02-2023)“…The capture of a soft spherical particle in a rectangular slit leads to a nonmonotonic pressure-flow rate relation at low Reynolds number. Simulations reveal…”
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Intermittent Pili-Mediated Forces Fluidize Neisseria meningitidis Aggregates Promoting Vascular Colonization
Published in Cell (28-06-2018)“…Neisseria meningitidis, a bacterium responsible for meningitis and septicemia, proliferates and eventually fills the lumen of blood capillaries with…”
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Micropipette force probe to quantify single-cell force generation: application to T-cell activation
Published in Molecular biology of the cell (07-11-2017)“…In response to engagement of surface molecules, cells generate active forces that regulate many cellular processes. Developing tools that permit gathering…”
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Critical assessment of wall model numerical implementation in LBM
Published in Computers & fluids (15-05-2023)“…In this article, a thorough investigation of wall model numerical implementation at high Reynolds numbers is conducted. In the framework of combined Lattice…”
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Distinct timing of neutrophil spreading and stiffening during phagocytosis
Published in Biophysical journal (19-04-2022)“…Phagocytic cells form the first line of defense in an organism, engulfing microbial pathogens. Phagocytosis involves cell mechanical changes that are not yet…”
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