Search Results - "Hussain Asim, Mulazim"

Thiolated cyclodextrins: New perspectives for old excipients by Hussain Asim, Mulazim, Ijaz, Muhammad, Rösch, Alexandra Christiane, Bernkop-Schnürch, Andreas

“…•Thiolated cyclodextrins (CDS) are obtained by covalent attachment of thiol groups.•Inclusion complexes formed with thiolated CDs enhance drug…”
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Tetradeca-thiolated cyclodextrins: Highly mucoadhesive and in-situ gelling oligomers with prolonged mucosal adhesion by Hussain Asim, Mulazim, Nazir, Imran, Jalil, Aamir, Matuszczak, Barbara, Bernkop-Schnürch, Andreas

“…[Display omitted] •Tetradeca-thiolated β-CD was synthesized by a microwave-assisted method.•Thiol groups were stable at pH 4 but prone to oxidation at higher…”
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Investigating the in-vitro bioactivity, biodegradability and drug release behavior of the newly developed PES/HA/WS biocompatible nanocomposites as bone graft substitute by Salimi, Esmaeil, Asim, Mulazim Hussain, Abidin, Muhammad Nidzhom Zainol

“…The nucleation of carbonate-containing apatite on the biomaterials surface is regarded as a significant stage in bone healing process. In this regard,…”
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Zeta potential changing self-nanoemulsifying drug delivery systems: A newfangled approach for enhancing oral bioavailability of poorly soluble drugs by Arshad, Amina, Arshad, Shumaila, Alamgeer, Mahmood, Arshad, Hussain Asim, Mulazim, Ijaz, Muhammad, Muhammad Irfan, Hafiz, Rubab, Mavra, Ali, Shujaat, Raza Hashmi, Ahmed

“…[Display omitted] The mucus is a defensive barrier for different drug-loaded systems. To overcome this obstacle, the crucial factor is the surface charge. Due…”
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Development of pre-activated α-cyclodextrin as a mucoadhesive excipient for intra-vesical drug delivery by Ijaz, Muhammad, Prantl, Maximilian, Lupo, Noemi, Laffleur, Flavia, Hussain Asim, Mulazim, Matuszczak, Barbara, Bernkop-Schnürch, Andreas

“…[Display omitted] The study was designed to synthesize and characterize pre-activated α-cyclodextrin (α-CD) derivatives as mucus adhering excipients for…”
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S-Protected thiolated nanostructured lipid carriers exhibiting improved mucoadhesive properties by Arshad, Shumaila, Masood-ur-Rehman, Hussain Asim, Mulazim, Nazir, Imran, Shahzadi, Iram, Mousli, Marc, Bernkop-Schnürch, Andreas

“…[Display omitted] •S-protected thiolated fatty acid conjugate was synthesized by amide bond formation.•Drug loaded NLCs were prepared by nano-template…”
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Enhanced Intestinal Permeability of Cefixime by Self-Emulsifying Drug Delivery System: In-Vitro and Ex-Vivo Characterization by Mahmood, Arshad, Khan, Laraib, Ijaz, Muhammad, Nazir, Imran, Naseem, Mahrukh, Tahir, Muhammad Azam, Aamir, Muhammad Naeem, Rehman, Masood Ur, Asim, Mulazim Hussain

“…Cefixime (CFX) belongs to a group of third-generation cephalosporin antibiotics with low water solubility and low intestinal permeability, which ultimately…”
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In-depth drug delivery to tumoral soft tissues via pH responsive hydrogel by Sarwar, Shumaila, Bashir, Sajid, Asim, Mulazim Hussain, Ikram, Fakhera, Ahmed, Arsalan, Omema, Ume, Asif, Anila, Chaudhry, Aqif Anwar, Hu, Yong, Ustundag, Cem Bulent

“…A pH responsive nanoparticle–hydrogel hybrid drug delivery system was investigated for in-depth anticancer drug delivery to solid tumours. It consists of acid…”
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Nano-Formulation Based Intravesical Drug Delivery Systems: An Overview of Versatile Approaches to Improve Urinary Bladder Diseases by Sarfraz, Muhammad, Qamar, Shaista, Rehman, Masood Ur, Tahir, Muhammad Azam, Ijaz, Muhammad, Ahsan, Anam, Asim, Mulazim Hussain, Nazir, Imran

“…Intravesical drug delivery is a direct drug delivery approach for the treatment of various bladder diseases. The human urinary bladder has distinctive anatomy,…”
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Antihypertensive and Vasorelaxant Effects of Citrus aurantifolia Linn. Fruit: Proposed Mechanisms by Bukhari, Syed Nasir Abbas, Alamgeer, Saeed, Sumera, Asim, Mulazim Hussain, Irfan, Hafiz Muhammad, Ejaz, Hasan, Elsherif, Mervat A., Junaid, Kashaf

“…Background. Citrus aurantifolia Linn. fruit, a natural dietary item, has long been used traditionally to treat hypertension in Pakistan. The current research…”
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Ex vivo, in vitro, and in silico approaches to unveil the mechanisms underlying vasorelaxation effect of Mentha Longifolia (L.) in porcine coronary artery by Alamgeer, Asif, Hira, Chohan, Tahir Ali, Irfan, Hafiz Muhammad, Asim, Mulazim Hussain, Bukhari, Syed Nasir Abbas, Younis, Waqas, Althobaiti, Yusuf S., Ullah, Aman, Khan, Abdul Qayyum, Hakami, Alqassem Y.

“…Mentha (M.) longifolia (L.) is traditionally used for various ailments. The current study was intended to explore the underlying vasorelaxation mechanisms of…”
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Safety and Pharmaceutical Evaluation of a Novel Natural Polymer, Ocicum, as Solubility and Dissolution Enhancer in Solid Dispersion by Manzoor, Mobina, Raza, Syed Atif, Asim, Mulazim Hussain, Bukhari, Nadeem Irfan, Arshad, Shumaila, Zafar, Uzma

“…Plant mucilages are commonly employed as excipients in pharmaceutical manufacturing. Ocimum basilicum (Lamiaceae family), a source of hydrophilic mucilage…”
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Development and Characterization of Thiolated Cyclodextrin-Based Nanoparticles for Topical Delivery of Minoxidil by Akhtar, Ammara, Waqas, Muhammad Khurram, Mahmood, Arshad, Tanvir, Saira, Hussain, Talib, Kazi, Mohsin, Ijaz, Muhammad, Asim, Mulazim Hussain

“…The aim of this research was to prepare adhesive nanoparticles for the topical application of Minoxidil (MXD). Thiolated β-CDs were prepared via conjugation of…”
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Compatibility analysis of bergapten with different pharmaceutical excipients used in nanostructured lipid carriers by Arshad, Shumaila, Rehman, Maqsoodur, Zulfiqar, Juwairiya, Najam, Saima, Asim, Mulazim Hussain, Abid, Farah

“…In pharmaceuticals sciences, Fourier-transform infrared spectroscopy (FTIR) is a very useful technique to measure the compatibility and interaction between…”
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Non-ionic thiolated cyclodextrins - the next generation by Moghadam, Ali, Ijaz, Muhammad, Asim, Mulazim Hussain, Mahmood, Arshad, Jelkmann, Max, Matuszczak, Barbara, Bernkop-Schnürch, Andreas

“…The current study was aimed at developing a novel mucoadhesive thiolated cyclodextrin (CD) without ionizable groups and an intact ring backbone for drug…”
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Impact of pharmacist-led interventions in improving adherence to glaucoma medications in the geriatric population by Aleem, Ayesha, Amin, Fatima, Asim, Mulazim Hussain, Farooq, Nayab, Arshad, Shumaila, Raziq, Mairah

“…ObjectivesGeriatric patients can be non-adherent to ophthalmic glaucoma medications because of complex eye drops instillation techniques and forgetfulness, so…”
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Ethyl-acetate extract of tara mira (Eruca sativa) alleviates the inflammation and rheumatoid arthritis in rats by Ikram, Javaria, Alamgeer, -, Muhammad Irfan, Hafiz, Akram, Muhammad, Hussain Asim, Mulazim, Hadal Alotaibi, Nasser, Saad Alharbi, Khalid, Abbas Bukhari, Syed Nasir, Qasim, Sumera, Niazi, Zahid Rasul

“…Eruca sativa, member of family Brassicaceae, was evaluated for its anti-arthritic potential. Both in vitro and in vivo models were used to bring out a safe,…”
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Protective Effect of Butanolic Fraction of Delphinium brunonianum on Fructose-Mediated Metabolic Alterations in Rats by Bukhari, Syed Nasir Abbas, Asif, Hira, Alamgeer, Asim, Mulazim Hussain, Muhammad Irfan, Hafiz, Ejaz, Hasan, Elsherif, Mervat A., Junaid, Kashaf

“…The present study was conducted with an intent to evaluate the protective effect of butanolic fraction of Delphinium brunonianum on fructose mediated metabolic…”
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Self-emulsifying drug delivery systems: Impact of stability of hydrophobic ion pairs on drug release by Nazir, Imran, Asim, Mulazim Hussain, Dizdarević, Aida, Bernkop-Schnürch, Andreas

“…[Display omitted] The aim of this study was to evaluate the impact of stability of hydrophobic ion pairs (HIPs) in gastrointestinal (GI) fluids on their…”
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Thiolated cyclodextrins: Mucoadhesive and permeation enhancing excipients for ocular drug delivery by Asim, Mulazim Hussain, Ijaz, Muhammad, Mahmood, Arshad, Knoll, Patrick, Jalil, Aamir, Arshad, Shumaila, Bernkop-Schnürch, Andreas

“…[Display omitted] •Thiolated β-CD was synthesized by replacing primary –OH groups with thiol groups.•Thiolated β-CD showed no inflammation on ocular mucosa…”
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