Search Results - "Hussain, Saira"
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Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein
Published in Nature communications (21-10-2020)“…The CR3022 antibody, selected from a group of SARS-CoV monoclonal antibodies for its ability to cross-react with SARS-CoV-2, has been examined for its ability…”
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Evolution of the SARS-CoV-2 spike protein in the human host
Published in Nature communications (04-03-2022)“…Recently emerged variants of SARS-CoV-2 contain in their surface spike glycoproteins multiple substitutions associated with increased transmission and…”
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SARS-CoV-2 S2-targeted vaccination elicits broadly neutralizing antibodies
Published in Science translational medicine (27-07-2022)“…Several variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have emerged during the current coronavirus disease 2019 (COVID-19) pandemic…”
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A Cytomegalovirus (CMV) Case Study to Promote Interprofessional Learning (IPL) Between Audiology and Biomedical Science Students in Higher Education
Published in British journal of biomedical science (29-11-2023)“…Modern and effective patient care requires specialist healthcare professionals working together. Interprofessional learning (IPL) seeks to provide…”
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Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains
Published in eLife (29-07-2021)“…Background: The degree of heterotypic immunity induced by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains is a major determinant of the…”
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Breadth and function of antibody response to acute SARS-CoV-2 infection in humans
Published in PLoS pathogens (01-02-2021)“…Serological and plasmablast responses and plasmablast-derived IgG monoclonal antibodies (MAbs) have been analysed in three COVID-19 patients with different…”
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Molecular Characterization of Influenza C Viruses from Outbreaks in Hong Kong SAR, China
Published in Journal of virology (14-10-2020)“…In 2014, the Centre for Health Protection in Hong Kong introduced screening for influenza C virus (ICV) as part of its routine surveillance for infectious…”
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Protease Inhibitors Purified from the Canola Meal Extracts of Two Genetically Diverse Genotypes Exhibit Antidiabetic and Antihypertension Properties
Published in Molecules (Basel, Switzerland) (04-04-2021)“…Valorization of vegetable oil waste residues is gaining importance due to their high protein and polyphenol contents. Protease inhibitors (PIs), proteins from…”
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Protocol for the development and validation of a patient-reported experience measure (PREM) for people with hearing loss: the PREM-HeLP
Published in BMJ open (29-11-2023)“…IntroductionHearing loss is a common chronic health condition and adversely affects communication and social function resulting in loneliness, social isolation…”
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Mutation of Influenza A Virus PA-X Decreases Pathogenicity in Chicken Embryos and Can Increase the Yield of Reassortant Candidate Vaccine Viruses
Published in Journal of virology (15-01-2019)“…The PA-X protein of influenza A virus has roles in host cell shutoff and viral pathogenesis. While most strains are predicted to encode PA-X, strain-dependent…”
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Protocol for a qualitative study exploring the lived experience of hearing loss and patient reported experience in the UK: the HeLP study
Published in BMJ open (07-06-2023)“…IntroductionWorldwide, hearing loss is a significant public health issue and one of the most common chronic health conditions experienced by older adults…”
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Staphylococcus aureus Lipase 1 Enhances Influenza A Virus Replication
Published in mBio (07-07-2020)“…Influenza A virus (IAV) causes annual epidemics of respiratory disease in humans, often complicated by secondary coinfection with bacterial pathogens such as…”
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Electron cryotomography of SARS-CoV-2 virions reveals cylinder-shaped particles with a double layer RNP assembly
Published in Communications biology (10-11-2022)“…SARS-CoV-2 is a lipid-enveloped Betacoronavirus and cause of the Covid-19 pandemic. To study the three-dimensional architecture of the virus, we perform…”
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Correction: Breadth and function of antibody response to acute SARS-CoV-2 infection in humans
Published in PLoS pathogens (10-12-2021)“…[This corrects the article DOI: 10.1371/journal.ppat.1009352.]…”
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Extraction, Chemical Characterization, In Vitro Antioxidant, and Antidiabetic Activity of Canola (Brassica napus L.) Meal
Published in Separations (01-02-2022)“…Canola (Brassica napus L.) meal is a by-product after oil extraction from canola seed and is of relatively low value. This meal may have additional value in…”
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Effect of contact lens material on in-vitro wettability in adverse environmental conditions
Published in Contact lens & anterior eye (01-06-2018)Get full text
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Increases in C-Reactive Protein May Predict Recurrence of Clozapine-Induced Fever
Published in The Annals of pharmacotherapy (01-01-2009)“…OBJECTIVE To report a case of recurrent clozapine-induced fever that was associated with a rise in C-reactive protein (CRP). CASE SUMMARY A 73-year-old man…”
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Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination
Published in The Lancet (British edition) (19-06-2021)Get full text
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Preexisting and de novo humoral immunity to SARS-CoV-2 in humans
Published in Science (American Association for the Advancement of Science) (11-12-2020)“…Zoonotic introduction of novel coronaviruses may encounter preexisting immunity in humans. Using diverse assays for antibodies recognizing SARS-CoV-2 proteins,…”
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AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC
Published in The Lancet (British edition) (17-07-2021)“…Two doses of AZD1222 generated NAb activity against the Wildtype strain bearing a spike identical to that encoded by the vaccine in all participants (median…”
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