Search Results - "Hussain, Rehan M."

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    Vascular Endothelial Growth Factor Antagonists: Promising Players in the Treatment of Neovascular Age-Related Macular Degeneration by Hussain, Rehan M, Shaukat, Bilal A, Ciulla, Lauren M, Berrocal, Audina M, Sridhar, Jayanth

    Published in Drug design, development and therapy (01-01-2021)
    “…Neovascular age-related macular degeneration (nAMD) treatment has been revolutionized by the introduction of vascular endothelial growth factor antagonists…”
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    Brolucizumab for persistent macular fluid in neovascular age-related macular degeneration after prior anti-VEGF treatments by Hussain, Rehan M., Neal, Andrea, Yannuzzi, Nicolas A., Patel, Kevin H., Huo, Siya, Hariprasad, Seenu M., Bhatia, Sumit P.

    Published in Therapeutic advances in ophthalmology (01-01-2021)
    “…Background: Some patients with neovascular age-related macular degeneration (nAMD) have persistent intraretinal/subretinal fluid (IRF/SRF) despite being…”
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    Chorioretinal Coloboma Complications: Retinal Detachment and Choroidal Neovascular Membrane by Hussain, Rehan M, Abbey, Ashkan M, Shah, Ankoor R, Drenser, Kimberly A, Trese, Michael T, Capone, Jr, Antonio

    Published in Journal of ophthalmic & vision research (01-01-2017)
    “…To report the chorioretinal coloboma, and its association with increased risk of retinal detachment (RD) and choroidal neovascularization (CNV). This…”
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    Complement inhibition as a therapeutic strategy in retinal disorders by Kassa, Enoch, Ciulla, Thomas A, Hussain, Rehan M, Dugel, Pravin U

    Published in Expert opinion on biological therapy (03-04-2019)
    “…Dry age-related macular degeneration (AMD) and Stargardt Macular Dystrophy (STGD1) result in vision loss due to progressive atrophy of the macula and lack of…”
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    Pars plana vitrectomy with intraoperative optical coherence tomography for sub-internal limiting membrane fibrosis excision in a child with Terson syndrome: Surgical and pathological correlation by Hussain, Rehan M, Dubovy, Sander R, Zhou, Xiao Yi, Schwartz, Stephen G, Villegas, Victor M

    “…To report the intraoperative optical coherence tomography (OCT)-guided surgery of a consolidated sub-internal limiting membrane (ILM) hemorrhage that developed…”
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    Treatment strategies for refractory diabetic macular edema: switching anti-VEGF treatments, adopting corticosteroid-based treatments, and combination therapy by Hussain, Rehan M, Ciulla, Thomas A

    Published in Expert opinion on biological therapy (03-03-2016)
    “…The pathophysiology of diabetic macular edema (DME) is complex, involving vascular endothelial growth factor (VEGF) and other inflammatory mediators. DME is…”
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    Emerging vascular endothelial growth factor antagonists to treat neovascular age-related macular degeneration by Hussain, Rehan M, Ciulla, Thomas A

    Published in Expert opinion on emerging drugs (03-07-2017)
    “…Evolving anti-vascular endothelial growth factor (VEGF) treatments for neovascular age-related macular degeneration (nAMD) include long acting agents,…”
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    Visual Acuity Outcomes and Anti-Vascular Endothelial Growth Factor Therapy Intensity in Neovascular Age-Related Macular Degeneration Patients: A Real-World Analysis of 49 485 Eyes by Ciulla, Thomas A, Hussain, Rehan M, Pollack, John S, Williams, David F

    Published in Ophthalmology retina (01-01-2020)
    “…This study assessed anti-vascular endothelial growth factor (VEGF) therapy intensity and its relationship with visual acuity (VA) change in real-world…”
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    Voretigene neparvovec-rzyl for treatment of RPE65 -mediated inherited retinal diseases: a model for ocular gene therapy development by Ciulla, Thomas A, Hussain, Rehan M, Berrocal, Audina M, Nagiel, Aaron

    Published in Expert opinion on biological therapy (02-06-2020)
    “…: Over a decade of research and development culminated in the 2017 United States (US) Food and Drug Administration (FDA) approval of voretigene neparvovec-rzyl…”
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    Gene therapy for age-related macular degeneration by Moore, Nicholas A, Bracha, Peter, Hussain, Rehan M, Morral, Nuria, Ciulla, Thomas A

    Published in Expert opinion on biological therapy (03-10-2017)
    “…In neovascular age related macular degeneration (nAMD), gene therapy to chronically express anti-vascular endothelial growth factor (VEGF) proteins could…”
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    LEAN SIX SIGMA TECHNIQUES TO IMPROVE OPHTHALMOLOGY CLINIC EFFICIENCY by Ciulla, Thomas A, Tatikonda, Mohan V, ElMaraghi, Yehya A, Hussain, Rehan M, Hill, Amanda L, Clary, Julie M, Hattab, Eyas

    Published in Retina (Philadelphia, Pa.) (01-09-2018)
    “…Ophthalmologists serve an increasing volume of a growing elderly population undergoing increasingly complex outpatient medical care, including extensive…”
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    Voretigene Neparvovec in Retinal Diseases: A Review of the Current Clinical Evidence by Gao, Jie, Hussain, Rehan M, Weng, Christina Y

    Published in Clinical ophthalmology (Auckland, N.Z.) (01-01-2020)
    “…Subretinal gene therapy trials began with the discovery of RPE65 variants and their association with Leber congenital amaurosis. The RPE65 protein is critical…”
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    Sutureless scleral fixation of intraocular lenses: outcomes of two approaches. The 2014 Yasuo Tano Memorial Lecture by Abbey, Ashkan M., Hussain, Rehan M., Shah, Ankoor R., Faia, Lisa J., Wolfe, Jeremy D., Williams, George A.

    “…Purpose We sought to assess the clinical outcomes and complications of two approaches to scleral fixation of intraocular lenses (IOLs): transconjunctival…”
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    Pharmacotherapy of retinal disease with visual cycle modulators by Hussain, Rehan M, Gregori, Ninel Z, Ciulla, Thomas A, Lam, Byron L

    Published in Expert opinion on pharmacotherapy (24-03-2018)
    “…Pharmacotherapy with visual cycle modulators (VCMs) is under investigation for retinitis pigmentosa (RP), Leber congenital amaurosis (LCA), Stargardt macular…”
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    Baseline retrobulbar blood flow is associated with both functional and structural glaucomatous progression after 4 years by Moore, Nicholas A, Harris, Alon, Wentz, Scott, Verticchio Vercellin, Alice Chandra, Parekh, Priyanka, Gross, Joshua, Hussain, Rehan M, Thieme, Claudia, Siesky, Brent

    Published in British journal of ophthalmology (01-03-2017)
    “…Previous studies suggest that vascular abnormalities are involved in the pathogenesis of open-angle glaucoma. This study aims to examine the relationship of…”
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    Abicipar pegol for neovascular age-related macular degeneration by Hussain, Rehan M, Weng, Christina Y, Wykoff, Charles C, Gandhi, Raya A, Hariprasad, Seenu M

    Published in Expert opinion on biological therapy (01-09-2020)
    “…The development of intravitreal anti-vascular endothelial growth factor (VEGF) therapy has revolutionized management of neovascular age-related macular…”
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    RANIBIZUMAB FOR DIABETIC MACULAR EDEMA REFRACTORY TO MULTIPLE PRIOR TREATMENTS by Ciulla, Thomas A, Hussain, Rehan M, Ciulla, Lauren M, Sink, Bethany, Harris, Alon

    Published in Retina (Philadelphia, Pa.) (01-07-2016)
    “…Diabetic macular edema can be refractory to multiple treatment modalities. Although there have been anecdotal reports of ranibizumab showing efficacy when…”
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