Search Results - "Hussain, Rehan M."
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Vascular Endothelial Growth Factor Antagonists: Promising Players in the Treatment of Neovascular Age-Related Macular Degeneration
Published in Drug design, development and therapy (01-01-2021)“…Neovascular age-related macular degeneration (nAMD) treatment has been revolutionized by the introduction of vascular endothelial growth factor antagonists…”
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Purtscher's Retinopathy
Published in Ophthalmology (Rochester, Minn.) (01-08-2016)Get full text
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Brolucizumab for persistent macular fluid in neovascular age-related macular degeneration after prior anti-VEGF treatments
Published in Therapeutic advances in ophthalmology (01-01-2021)“…Background: Some patients with neovascular age-related macular degeneration (nAMD) have persistent intraretinal/subretinal fluid (IRF/SRF) despite being…”
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Chorioretinal Coloboma Complications: Retinal Detachment and Choroidal Neovascular Membrane
Published in Journal of ophthalmic & vision research (01-01-2017)“…To report the chorioretinal coloboma, and its association with increased risk of retinal detachment (RD) and choroidal neovascularization (CNV). This…”
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Complement inhibition as a therapeutic strategy in retinal disorders
Published in Expert opinion on biological therapy (03-04-2019)“…Dry age-related macular degeneration (AMD) and Stargardt Macular Dystrophy (STGD1) result in vision loss due to progressive atrophy of the macula and lack of…”
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Pars plana vitrectomy with intraoperative optical coherence tomography for sub-internal limiting membrane fibrosis excision in a child with Terson syndrome: Surgical and pathological correlation
Published in American journal of ophthalmology case reports (01-09-2019)“…To report the intraoperative optical coherence tomography (OCT)-guided surgery of a consolidated sub-internal limiting membrane (ILM) hemorrhage that developed…”
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Treatment strategies for refractory diabetic macular edema: switching anti-VEGF treatments, adopting corticosteroid-based treatments, and combination therapy
Published in Expert opinion on biological therapy (03-03-2016)“…The pathophysiology of diabetic macular edema (DME) is complex, involving vascular endothelial growth factor (VEGF) and other inflammatory mediators. DME is…”
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Emerging vascular endothelial growth factor antagonists to treat neovascular age-related macular degeneration
Published in Expert opinion on emerging drugs (03-07-2017)“…Evolving anti-vascular endothelial growth factor (VEGF) treatments for neovascular age-related macular degeneration (nAMD) include long acting agents,…”
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Visual Acuity Outcomes and Anti-Vascular Endothelial Growth Factor Therapy Intensity in Neovascular Age-Related Macular Degeneration Patients: A Real-World Analysis of 49 485 Eyes
Published in Ophthalmology retina (01-01-2020)“…This study assessed anti-vascular endothelial growth factor (VEGF) therapy intensity and its relationship with visual acuity (VA) change in real-world…”
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Voretigene neparvovec-rzyl for treatment of RPE65 -mediated inherited retinal diseases: a model for ocular gene therapy development
Published in Expert opinion on biological therapy (02-06-2020)“…: Over a decade of research and development culminated in the 2017 United States (US) Food and Drug Administration (FDA) approval of voretigene neparvovec-rzyl…”
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The role of retrobulbar and retinal circulation on optic nerve head and retinal nerve fibre layer structure in patients with open-angle glaucoma over an 18-month period
Published in British journal of ophthalmology (01-05-2015)“…Evidence suggests that vascular abnormalities play a role in the pathogenesis of open-angle glaucoma (OAG) in some patients. This study aims to assess changes…”
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Gene therapy for age-related macular degeneration
Published in Expert opinion on biological therapy (03-10-2017)“…In neovascular age related macular degeneration (nAMD), gene therapy to chronically express anti-vascular endothelial growth factor (VEGF) proteins could…”
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LEAN SIX SIGMA TECHNIQUES TO IMPROVE OPHTHALMOLOGY CLINIC EFFICIENCY
Published in Retina (Philadelphia, Pa.) (01-09-2018)“…Ophthalmologists serve an increasing volume of a growing elderly population undergoing increasingly complex outpatient medical care, including extensive…”
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Voretigene Neparvovec in Retinal Diseases: A Review of the Current Clinical Evidence
Published in Clinical ophthalmology (Auckland, N.Z.) (01-01-2020)“…Subretinal gene therapy trials began with the discovery of RPE65 variants and their association with Leber congenital amaurosis. The RPE65 protein is critical…”
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Sutureless scleral fixation of intraocular lenses: outcomes of two approaches. The 2014 Yasuo Tano Memorial Lecture
Published in Graefe's archive for clinical and experimental ophthalmology (01-01-2015)“…Purpose We sought to assess the clinical outcomes and complications of two approaches to scleral fixation of intraocular lenses (IOLs): transconjunctival…”
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Pharmacotherapy of retinal disease with visual cycle modulators
Published in Expert opinion on pharmacotherapy (24-03-2018)“…Pharmacotherapy with visual cycle modulators (VCMs) is under investigation for retinitis pigmentosa (RP), Leber congenital amaurosis (LCA), Stargardt macular…”
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Differentiating Veins From Arteries on Optical Coherence Tomography Angiography by Identifying Deep Capillary Plexus Vortices
Published in American journal of ophthalmology (01-11-2019)“…To introduce a simple method for differentiating retinal veins from arteries on optical coherence tomography angiography (OCTA). Cross-sectional pilot study…”
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Baseline retrobulbar blood flow is associated with both functional and structural glaucomatous progression after 4 years
Published in British journal of ophthalmology (01-03-2017)“…Previous studies suggest that vascular abnormalities are involved in the pathogenesis of open-angle glaucoma. This study aims to examine the relationship of…”
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Abicipar pegol for neovascular age-related macular degeneration
Published in Expert opinion on biological therapy (01-09-2020)“…The development of intravitreal anti-vascular endothelial growth factor (VEGF) therapy has revolutionized management of neovascular age-related macular…”
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RANIBIZUMAB FOR DIABETIC MACULAR EDEMA REFRACTORY TO MULTIPLE PRIOR TREATMENTS
Published in Retina (Philadelphia, Pa.) (01-07-2016)“…Diabetic macular edema can be refractory to multiple treatment modalities. Although there have been anecdotal reports of ranibizumab showing efficacy when…”
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