Search Results - "Huson, Vincent"

Graded heterogeneity of metabotropic signaling underlies a continuum of cell-intrinsic temporal responses in unipolar brush cells by Guo, Chong, Huson, Vincent, Macosko, Evan Z., Regehr, Wade G.

“…Many neuron types consist of populations with continuously varying molecular properties. Here, we show a continuum of postsynaptic molecular properties in…”
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Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi by Emperador-Melero, Javier, Huson, Vincent, van Weering, Jan, Bollmann, Christian, Fischer von Mollard, Gabriele, Toonen, Ruud F., Verhage, Matthijs

“…The SNAREs Vti1a/1b are implicated in regulated secretion, but their role relative to canonical exocytic SNAREs remains elusive. Here, we show that synaptic…”
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Post-tetanic potentiation lowers the energy barrier for synaptic vesicle fusion independently of Synaptotagmin-1 by Huson, Vincent, Meijer, Marieke, Dekker, Rien, Ter Veer, Mirelle, Ruiter, Marvin, van Weering, Jan Rt, Verhage, Matthijs, Cornelisse, Lennart Niels

“…Previously, we showed that modulation of the energy barrier for synaptic vesicle fusion boosts release rates supralinearly (Schotten, 2015). Here we show that…”
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Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate by Schotten, Sebastiaan, Meijer, Marieke, Walter, Alexander Matthias, Huson, Vincent, Mamer, Lauren, Kalogreades, Lawrence, ter Veer, Mirelle, Ruiter, Marvin, Brose, Nils, Rosenmund, Christian, Sørensen, Jakob Balslev, Verhage, Matthijs, Cornelisse, Lennart Niels

“…The energy required to fuse synaptic vesicles with the plasma membrane ('activation energy') is considered a major determinant in synaptic efficacy. From…”
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Correction: Additive effects on the energy barrier for synaptic vesicle fusion cause supralinear effects on the vesicle fusion rate by Schotten, Sebastiaan, Meijer, Marieke, Walter, Alexander Matthias, Huson, Vincent, Mamer, Lauren, Kalogreades, Lawrence, Veer, Mirelle Ter, Ruiter, Marvin, Brose, Nils, Rosenmund, Christian, Sørensen, Jakob Balslev, Verhage, Matthijs, Cornelisse, Lennart Niels

“…Schotten S, Meijer M, Walter AM, Huson V, Mamer L, Kalogreades L, ter Veer M, Ruiter M, Brose N, Rosenmund C, Sørensen JB, Verhage M, Cornelisse LN. 2015…”
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Diverse roles of Synaptotagmin-7 in regulating vesicle fusion by Huson, Vincent, Regehr, Wade G

“…•Syt7 is a Ca sensor for facilitation, asynchronous release, and replenishment.•Facilitation by Syt7 can allow depressing synapses to be frequency…”
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A Continuum of Response Properties across the Population of Unipolar Brush Cells in the Dorsal Cochlear Nucleus by Huson, Vincent, Newman, Leannah, Regehr, Wade G

“…Unipolar brush cells (UBCs) in the cerebellum and dorsal cochlear nucleus (DCN) perform temporal transformations by converting brief mossy fiber bursts into…”
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Synaptotagmin-1 enables frequency coding by suppressing asynchronous release in a temperature dependent manner by Huson, Vincent, van Boven, Maaike A., Stuefer, Alexia, Verhage, Matthijs, Cornelisse, L. Niels

“…To support frequency-coded information transfer, mammalian synapses tightly synchronize neurotransmitter release to action potentials (APs). However, release…”
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Publisher Correction: Synaptotagmin-1 enables frequency coding by suppressing asynchronous release in a temperature dependent manner by Huson, Vincent, van Boven, Maaike A., Stuefer, Alexia, Verhage, Matthijs, Cornelisse, L. Niels

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Presynaptic inhibition upon CB1 or mGlu2/3 receptor activation requires ERK/MAPK phosphorylation of Munc18-1 by Schmitz, Sabine K, King, Cillian, Kortleven, Christian, Huson, Vincent, Kroon, Tim, Kevenaar, Josta T, Schut, Desiree, Saarloos, Ingrid, Hoetjes, Joost P, de Wit, Heidi, Stiedl, Oliver, Spijker, Sabine, Li, Ka Wan, Mansvelder, Huibert D, Smit, August B, Cornelisse, Lennart Niels, Verhage, Matthijs, Toonen, Ruud F

“…Presynaptic cannabinoid (CB1R) and metabotropic glutamate receptors (mGluR2/3) regulate synaptic strength by inhibiting secretion. Here, we reveal a…”
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Presynaptic inhibition upon CB 1 or mG lu2/3 receptor activation requires ERK / MAPK phosphorylation of Munc18‐1 by Schmitz, Sabine K, King, Cillian, Kortleven, Christian, Huson, Vincent, Kroon, Tim, Kevenaar, Josta T, Schut, Desiree, Saarloos, Ingrid, Hoetjes, Joost P, de Wit, Heidi, Stiedl, Oliver, Spijker, Sabine, Li, Ka Wan, Mansvelder, Huibert D, Smit, August B, Cornelisse, Lennart Niels, Verhage, Matthijs, Toonen, Ruud F

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