Search Results - "Husni, Elaine"
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Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis
Published in The New England journal of medicine (29-12-2016)“…This randomized trial involving patients with osteoarthritis or rheumatoid arthritis who were at increased cardiovascular risk showed the noninferiority of…”
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Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis
Published in Arthritis research & therapy (08-06-2018)“…Rheumatoid arthritis (RA) patients are at high risk of developing cardiovascular disease (CVD). In RA, chronic inflammation may lead to endothelial…”
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3
Type 2 diabetes and osteoarthritis: a systematic review and meta-analysis
Published in Journal of diabetes and its complications (01-07-2016)“…Abstract Background Observational studies have reported an association between type 2 diabetes and osteoarthritis (OA) development and progression. However no…”
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Comorbidities in Psoriatic Arthritis
Published in Rheumatic diseases clinics of North America (01-11-2015)“…Epidemiologic studies have shown that, in patients with psoriatic arthritis (PsA), associated comorbidities may occur more frequently than expected. This…”
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Group for Research and Assessment of Psoriasis and Psoriatic Arthritis 2015 Treatment Recommendations for Psoriatic Arthritis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-05-2016)“…Objective To update the 2009 Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations for the spectrum of…”
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6
Recommendations for the Use of Nonsteroidal Anti-inflammatory Drugs and Cardiovascular Disease Risk: Decades Later, Any New Lessons Learned?
Published in Rheumatic diseases clinics of North America (01-02-2023)“…Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most prescribed pharmacologic therapies worldwide due to their therapeutic analgesic efficacy and…”
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Disease-specific composite measures for psoriatic arthritis are highly responsive to a Janus kinase inhibitor treatment that targets multiple domains of disease
Published in Arthritis research & therapy (29-10-2018)“…The multiple disease domains affected in psoriatic arthritis (PsA) may make composite endpoints appropriate for assessing changes in disease activity over…”
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The psychosocial burden of psoriatic arthritis
Published in Seminars in arthritis and rheumatism (01-12-2017)“…Abstract Objective To assess the psychosocial impact of psoriatic arthritis (PsA), describe how health-related quality of life (QoL) is affected in patients…”
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Breakthrough SARS–CoV‐2 Infections in Patients With Immune‐Mediated Disease Undergoing B Cell–Depleting Therapy: A Retrospective Cohort Analysis
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-12-2022)“…Objective Patients with immune‐mediated inflammatory diseases (IMIDs) receiving B cell–depleting therapy (BCDT) are among the most vulnerable to severe…”
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Measuring Outcomes in Psoriatic Arthritis: Comparing Routine Assessment of Patient Index Data and Psoriatic Arthritis Impact of Disease
Published in Journal of rheumatology (01-10-2020)“…To examine the construct validity of Routine Assessment of Patient Index Data 3 (RAPID3) and Psoriatic Arthritis Impact of Disease (PsAID) in patients with…”
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The impact of functional medicine on patient-reported outcomes in inflammatory arthritis: A retrospective study
Published in PloS one (08-10-2020)“…Despite treatment advances for inflammatory arthritis, a significant amount of patients fail to achieve remission. Other modifiable factors such as diet,…”
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Pooled safety results across phase 3 randomized trials of intravenous golimumab in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis
Published in Arthritis research & therapy (21-03-2022)“…Intravenous (IV) golimumab, a TNFi, is approved for treating rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). We analyzed…”
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What Clinical Factors Affect Length of Transition to Psoriatic Arthritis in Patients With Psoriasis?
Published in ACR open rheumatology (01-09-2024)“…Objective We aimed to identify clinical and demographic features associated with the interval between psoriasis (PsO) and psoriatic arthritis (PsA). Methods We…”
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Comparison of US patient, rheumatologist, and dermatologist perceptions of psoriatic disease symptoms: results from the DISCONNECT study
Published in Arthritis research & therapy (31-05-2018)“…The perceived bother of skin and joint-related manifestations of psoriatic disease may differ among patients, rheumatologists, and dermatologists. This study…”
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Radiographic Progression Inhibition with Intravenous Golimumab in Psoriatic Arthritis: Week 24 Results of a Phase III, Randomized, Double-blind, Placebo-controlled Trial
Published in Journal of rheumatology (01-06-2019)“…Evaluate effects of intravenous (IV) golimumab (GOL) on radiographic progression in psoriatic arthritis (PsA). This phase III, randomized, double-blind,…”
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The potential benefits of aspirin for primary cardiovascular prevention in rheumatoid arthritis: a secondary analysis of the PRECISION Trial
Published in Rheumatology (Oxford, England) (01-08-2018)“…Abstract Objective Guidelines exist for the use of low-dose aspirin in the general population for primary cardiovascular (CV) prevention, but the risk-benefit…”
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Management of Concomitant Inflammatory Bowel Disease or Uveitis in Patients with Psoriatic Arthritis: An Updated Review Informing the 2021 GRAPPA Treatment Recommendations
Published in Journal of rheumatology (01-03-2023)“…Several advanced therapies have been licensed across the related conditions of psoriatic arthritis (PsA), Crohn disease (CD), ulcerative colitis (UC), and…”
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Act1 is a negative regulator in T and B cells via direct inhibition of STAT3
Published in Nature communications (16-07-2018)“…Although Act1 (adaptor for IL-17 receptors) is necessary for IL-17-mediated inflammatory responses, Act1 - (but not Il17ra- , Il17rc- , or Il17rb -) deficient…”
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Evaluation of Improvement in Skin and Nail Psoriasis in Bio‐naïve Patients With Active Psoriatic Arthritis Treated With Golimumab: Results Through Week 52 of the GO‐VIBRANT Study
Published in ACR open rheumatology (01-11-2020)“…Objective To evaluate whether intravenous (IV) golimumab produces improvements in skin and nail symptoms that are concomitant with improvements in quality of…”
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Comprehensive Assessment of the Psoriasis Patient (CAPP): A Report from the GRAPPA 2015 Annual Meeting
Published in Journal of rheumatology (01-05-2016)“…Outcome measures for psoriasis severity are complex because of the heterogeneous presentation of the disease. At the 2015 annual meeting of the Group for…”
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