Search Results - "Husiev, Yurii"
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Simple and Efficient Method for Mono‐ and Di‐Amination of Polypyridine N‐Oxides
Published in European journal of organic chemistry (08-04-2024)“…Herein we report a simple synthetic route towards both known and novel aminated polypyridyl ligands. The use of tosyl chloride in combination with potassium…”
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Cyclic Ruthenium-Peptide Conjugates as Integrin-Targeting Phototherapeutic Prodrugs for the Treatment of Brain Tumors
Published in Journal of the American Chemical Society (12-07-2023)“…To investigate the potential of tumor-targeting photoactivated chemotherapy, a chiral ruthenium-based anticancer warhead, Λ/Δ-[Ru(Ph2phen)2(OH2)2]2+, was…”
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3
Red‐Light Activation of a Microtubule Polymerization Inhibitor via Amide Functionalization of the Ruthenium Photocage
Published in Angewandte Chemie International Edition (25-01-2024)“…Photoactivated chemotherapy (PACT) is a promising cancer treatment modality that kills cancer cells via photochemical uncaging of a cytotoxic drug. Most…”
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4
Fungal Anthraquinone Photoantimicrobials Challenge the Dogma of Cationic Photosensitizers
Published in Journal of natural products (Washington, D.C.) (27-10-2023)“…The photoantimicrobial potential of four mushroom species (i.e., Cortinarius cinnabarinus, C. holoxanthus, C. malicorius, and C. sanguineus) was explored by…”
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The Light-activated Effect of Natural Anthraquinone Parietin against Candida auris and Other Fungal Priority Pathogens
Published in Planta medica (01-06-2024)“…Antimicrobial photodynamic therapy (aPDT) is an evolving treatment strategy against human pathogenic microbes such as the species, including the emerging…”
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Oxygen-Dependent Interactions between the Ruthenium Cage and the Photoreleased Inhibitor in NAMPT-Targeted Photoactivated Chemotherapy
Published in Journal of medicinal chemistry (11-07-2024)“…Photoactivated chemotherapy agents form a new branch of physically targeted anticancer agents with potentially lower systemic side effects for patients. On the…”
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Photosubstitution in a trisheteroleptic ruthenium complex inhibits conjunctival melanoma growth in a zebrafish orthotopic xenograft model
Published in Chemical science (Cambridge) (15-06-2022)“…In vivo data are rare but essential for establishing the clinical potential of ruthenium-based photoactivated chemotherapy (PACT) compounds, a new family of…”
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A Lock‐and‐Kill Anticancer Photoactivated Chemotherapy Agent
Published in Photochemistry and photobiology (01-03-2023)“…Photosubstitutionally active ruthenium complexes show high potential as prodrugs for the photoactivated chemotherapy (PACT) treatment of tumors. One of the…”
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9
Red‐Light Activation of a Microtubule Polymerization Inhibitor via Amide Functionalization of the Ruthenium Photocage
Published in Angewandte Chemie (25-01-2024)“…Photoactivated chemotherapy (PACT) is a promising cancer treatment modality that kills cancer cells via photochemical uncaging of a cytotoxic drug. Most…”
Get full text
Journal Article