Search Results - "Husbeck, Bryan"

Inhibition of androgen receptor signaling by selenite and methylseleninic acid in prostate cancer cells: two distinct mechanisms of action by Husbeck, Bryan, Bhattacharyya, Rumi S, Feldman, David, Knox, Susan J

“…The development of prostate cancer and its progression to a hormone-refractory state is highly dependent on androgen receptor (AR) expression. Recent studies…”
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Redox modulation of human prostate carcinoma cells by selenite increases radiation-induced cell killing by Husbeck, Bryan, Peehl, Donna M., Knox, Susan J.

“…Although selenium compounds have been extensively studied as chemopreventative agents for prostate cancer, little is known about the potential use of selenium…”
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Selenite Treatment Inhibits LAPC-4 Tumor Growth and Prostate-Specific Antigen Secretion in a Xenograft Model of Human Prostate Cancer by Bhattacharyya, Rumi S., Ph.D, Husbeck, Bryan, Ph.D, Feldman, David, M.D, Knox, Susan J., Ph.D., M.D

“…Purpose Selenium compounds have known chemopreventive effects on prostate cancer. However selenite, an inorganic form of selenium, has not been extensively…”
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The redox protein thioredoxin-1 regulates the constitutive and inducible expression of the estrogen metabolizing cytochromes P450 1B1 and 1A1 in MCF-7 human breast cancer cells by Husbeck, Bryan, Powis, Garth

“…The oxidative metabolites of estrogen have been proposed to play an important role in the development of some human cancers. The two major pathways of estrogen…”
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Thioredoxin Peroxidase-1 (peroxiredoxin-1) Is Increased in Thioredoxin-1 Transfected Cells and Results in Enhanced Protection against Apoptosis Caused by Hydrogen Peroxide but Not by Other Agents Including Dexamethasone, Etoposide, and Doxorubicin by Berggren, Margareta I., Husbeck, Bryan, Samulitis, Betty, Baker, Amanda F., Gallegos, Alfred, Powis, Garth

“…Thioredoxin-1 (Trx-1) is a small redox oncoprotein whose expression is increased in a number of human primary cancers where it is associated with aggressive…”
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Radiation-Induced Cyclooxygenase 2 Up-Regulation is Dependent on Redox Status in Prostate Cancer Cells by Li, Lingyun, Steinauer, Kirsten K., Dirks, Amie J., Husbeck, Bryan, Gibbs, Iris, Knox, Susan J.

“…Li., L., Steinauer, K. L., Dirks, A. J., Husbeck, B., Gibbs, I. and Knox, S. J. Radiation-Induced Cyclooxygenase 2 Up-Regulation is Dependent on Redox Status…”
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Targeting Integrins and PI3K/Akt-Mediated Signal Transduction Pathways Enhances Radiation-Induced Anti-angiogenesis by Ning, Shoucheng, Chen, Zhijian, Dirks, Amie, Husbeck, Bryan, Hsu, Mark, Bedogni, Barbara, O'Neill, Melony, Powell, Marianne Broome, Knox, Susan J.

“…Ning, S., Chen, Z., Dirks, A., Husbeck, B., Hsu, M., Bedogni, B., O'Neill, M., Powell, M. B. and Knox, S. J. Targeting Integrins and PI3K/Akt-Mediated Signal…”
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DNA microarray reveals increased expression of thioredoxin peroxidase in thioredoxin-1 transfected cells and its functional consequences by Husbeck, B, Berggren, M I, Powis, G

“…The mammalian thioredoxins are a family of small redox proteins that undergo NADPH dependent reduction by thioredoxin reductase. Reduced thioredoxins reduce…”
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Changes in gene expression induced by thioredoxin-1 in MCF-7 human breast cancer cells by Husbeck, Bryan Edward

“…Thioredoxin-1 (Trx-1) is a small redox protein that is overexpressed in a number of human cancers. Elevated levels of Trx-1 in tumors is associated with…”
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